... (SCZ), despite contradictory findings from prior studies exploring the association between violence and SCZ. Evidence has shown that certain comorbidities, specifically the presence of a substance use disorders, can result in increased aggression in those with SCZ. Copy number variation (CNV) load has...

...Eugene A. Zubkov; Yana A. Zorkina; Elena V. Orshanskaya; Nadezhda N. Khlebnikova; Natalia A. Krupina; Vladimir P. Chekhonin Background: Previous studies have shown the development of emotional and motivational disorders, such as anxiety-depression-like disorders with increased aggression...

...Valentina A. Toshchakova; Yalda Bakhtiari; Alexander V. Kulikov; Sergey I. Gusev; Marina V. Trofimova; Olga Yu. Fedorenko; Ekaterina V. Mikhalitskaya; Nina K. Popova; Nikolay A. Bokhan; Johannes E. Hovens; Anton J.M. Loonen; Bob Wilffert; Svetlana A. Ivanova Background: Human aggression...

...Magnus Löfgren; Sara K. Bengtsson; Maja Johansson; Torbjörn Bäckström Background/Aims: Allopregnanolone or 3α-hydroxy-5α-pregnan-20-one (AlloP) is normally sedative and anxiolytic, but can under provoking circumstances paradoxically induce aggressive behavior. Therefore, it is of particular...

...Melanie Y. Baars; Matthias J. Müller; Bernd Gallhofer; Petra Netter Background: Personality traits like depression on the one hand and aggression and impulsivity on the other are assumed to be predisposing factors for different types of alcohol dependence. Both types are associated with sensitivity...

... History of Aggression Scale, the Psychopathy Checklist or recidivistic violent crime. No significant correlation was found between MAO-B and any of the monoamine metabolites. Analyses in subgroups of smokers/non-smokers did not change this overall result. Conclusions: The findings of the present study did...

...Youl-Ri Kim; Jeong Won Jahng; Sung Kil Min Background: The serotonin transporter-linked polymorphic region (5-HTTLPR) short allele confers a general sensitivity to environmental stimuli, and anger is suspected to have a direct influence on aggressive behavior in schizophrenia. In the present study...

...Yosef Sarne; Jacob Mandel; Mirtha H. Goncalves; Shlomo Brook; Michal Gafni; Avner Elizur The relationships between [ 3 H]imipramine binding to blood platelets and manifestation of aggressive behavior was studied in three different groups of subjects. Arrested offenders displayed high imipramine...

...P. Castrogiovanni; M.R. Capone; I. Maremmani; D. Marazziti The availability of peripheral markers of the serotonergic system, which appears to play a major role in aggressive behaviour, prompted us to investigate in healthy subjects the possible correlations between platelet 3 H-imipramine ( 3 H...

...I. Modai; A. Apter; M. Meltzer; S. Tyano; A. Walevski; Z. Jerushalmy Thirty-four adolescent psychiatric inpatients were studied in order to find out whether there is a correlation between serotonin platelet uptake (SPU), suicidality and aggression. The patients were divided into four main...

..., and the time spent submitting, to untreated rats intruding into their home-cage territory; it also significantly reduced the number of kicks directed at, and the time spent kicking, the intruder; and the incidence of, and time spent in, aggressively grooming the intruder. When the intruder rats were treated...

... platelet MAO activity subjects, consistent trends were observed in the direction of higher scores in the impulsivity scales, the sensation seeking-related Monotony avoidance scale, and the Indirect Aggression scale for both female and male low MAO activity groups © 1987 S. Karger AG, Basel 1987...

... to the existing medication as an adjuvant. The test substance was administered in a dose of 2 × 5 mg daily for the first 3 weeks, in a dose of 2 × 10 mg daily for the following 3 weeks. The addition of milenperone to the preexisting medication decreased the aggressiveness scores, significantly on the Paranoid...

... of the target symptoms were visualized on the Visual Analogue Line. Although, in the last 3 weeks of the study, the aggressiveness scores had decreased more in the milenperone group than in the placebo group, the difference between both studied groups was not significant. This lack of clear result may probably...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Social interaction Aggression...

... negative correlation between MAO activities and the traits reflecting verbal aggression and irritability was also found. A separate analysis showed that those correlations hold true for female but not for male patients. 19 2 2008 © 1984 S. Karger AG, Basel 1984 Copyright / Drug Dosage...

... patients appeared to be most deviant from the other groups in most variables. Statistically significant differences were obtained for the variable socialization, which measures the internalization of social rules on which the DSD patients scored lowest, and variables of aggression on which the DSD patients...

...C. Stadler; F.D. Zepf; L. Demisch; M. Schmitt; M. Landgraf; F. Poustka Background: The present study investigated the effects of rapid tryptophan depletion (RTD), and the ensuing reduction of central nervous system levels of serotonin (5-HT), upon reactive aggression in patients with attention...

...C. Stadler; K. Schmeck; I. Nowraty; W.E. Müller; F. Poustka Dysregulation of serotonergic function has been found to be associated with aggression in animals, human adults and adolescents. However, studies with children have shown conflicting results. The objective of this study was to investigate...

... and the Overt Aggression Scale (OAS) were administered to the autistic group as a measure of symptom severity. Results: Significantly lower PPP 5-HT levels were observed in the autistic group as compared to the controls (p = 0.03). In addition, PPP 5-HT levels were inversely correlated with OAS scores among...