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HFM1

From Wikipedia, the free encyclopedia
HFM1
Identifiers
AliasesHFM1, MER3, POF9, SEC63D1, Si-11, Si-11-6, helicase, ATP-dependent DNA helicase homolog, ATP dependent DNA helicase homolog, helicase for meiosis 1
External IDsOMIM: 615684; MGI: 3036246; HomoloGene: 87103; GeneCards: HFM1; OMA:HFM1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001017975

NM_001252516
NM_177873

RefSeq (protein)

NP_001017975

NP_001239445
NP_808541

Location (UCSC)Chr 1: 91.26 – 91.4 MbChr 5: 106.84 – 106.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

HFM1 is a gene that in humans encodes a protein necessary for homologous recombination of chromosomes.[5] Biallelic mutations in HFM1 cause recessive primary ovarian insufficiency.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162669Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043410Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Wang J, Zhang W, Jiang H, Wu BL (March 2014). "Mutations in HFM1 in recessive primary ovarian insufficiency". The New England Journal of Medicine. 370 (10): 972–4. doi:10.1056/NEJMc1310150. PMID 24597873.