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GNG11

From Wikipedia, the free encyclopedia
GNG11
Identifiers
AliasesGNG11, GNGT11, G protein subunit gamma 11, HG3H1
External IDsOMIM: 604390; MGI: 1913316; HomoloGene: 3045; GeneCards: GNG11; OMA:GNG11 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004126

NM_025331

RefSeq (protein)

NP_004117

NP_079607

Location (UCSC)Chr 7: 93.92 – 93.93 MbChr 6: 4 – 4.01 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 is a protein that in humans is encoded by the GNG11 gene.[5][6]

This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein.

As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000127920Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032766Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ray K, Kunsch C, Bonner LM, Robishaw JD (Oct 1995). "Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits". J Biol Chem. 270 (37): 21765–71. doi:10.1074/jbc.270.37.21765. PMID 7665596.
  6. ^ a b "Entrez Gene: GNG11 guanine nucleotide binding protein (G protein), gamma 11".

Further reading

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