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GABRG1

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GABRG1
Identifiers
AliasesGABRG1, gamma-aminobutyric acid type A receptor gamma1 subunit, gamma-aminobutyric acid type A receptor subunit gamma1
External IDsOMIM: 137166; MGI: 103156; HomoloGene: 22570; GeneCards: GABRG1; OMA:GABRG1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_173536

NM_010252

RefSeq (protein)

NP_775807

NP_034382

Location (UCSC)Chr 4: 46.04 – 46.12 MbChr 5: 70.91 – 71 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gamma-aminobutyric acid receptor subunit gamma-1 is a protein that in humans is encoded by the GABRG1 gene.[5] The protein encoded by this gene is a subunit of the GABAA receptor.[6]

Variants of this gene may be associated with alcohol dependence.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163285Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001260Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wilcox AS, Warrington JA, Gardiner K, Berger R, Whiting P, Altherr MR, Wasmuth JJ, Patterson D, Sikela JM (July 1992). "Human chromosomal localization of genes encoding the gamma 1 and gamma 2 subunits of the gamma-aminobutyric acid receptor indicates that members of this gene family are often clustered in the genome". Proc. Natl. Acad. Sci. U.S.A. 89 (13): 5857–5861. Bibcode:1992PNAS...89.5857W. doi:10.1073/pnas.89.13.5857. PMC 49396. PMID 1321425.
  6. ^ Hevers W, Lüddens H (August 1998). "The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes". Mol. Neurobiol. 18 (1): 35–86. doi:10.1007/BF02741459. PMID 9824848. S2CID 32359279.
  7. ^ Ittiwut C, Listman J, Mutirangura A, Malison R, Covault J, Kranzler HR, Sughondhabirom A, Thavichachart N, Gelernter J (January 2008). "Interpopulation linkage disequilibrium patterns of GABRA2 and GABRG1 genes at the GABA cluster locus on human chromosome 4". Genomics. 91 (1): 61–69. doi:10.1016/j.ygeno.2007.08.007. PMC 2709929. PMID 17976953.

Further reading

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