Comparative genomics of high grade neuroendocrine carcinoma of the cervix
Fig 3
Comparison of somatic mutation rate among cervical carcinomas and extra-cervical small cell carcinomas of the lung and bladder.
(A) Coding mutation burden by tumor type. Statistical comparisons were performed between NECC and each other tumor type using a two-sided Wilcoxon rank-sum test. (B) Fraction of mutated samples by tumor type for frequently mutated genes. For each gene, statistical comparisons were performed between the mutation rate of NECC and each other tumor type using a two-sided Fisher’s exact test. ***, p < .001; **, p < .01; *, p < .05; n.s. = not significant. SNV = single nucleotide variant, indel = small insertion/deletion, SCCB = small cell carcinoma of the bladder, SCLC = small cell lung carcinoma, NECC = small cell neuroendocrine carcinoma of the cervix, SCC = squamous carcinoma of the cervix, ACC = endocervical adenocarcinoma.
