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Comparative genomics of high grade neuroendocrine carcinoma of the cervix

Fig 2

Gene-adjacent HPV integration events in high grade neuroendocrine carcinoma of the cervix.

(A) Fraction of genome altered by copy number alterations (.3 > log CN ratio > -.3) as a function of tumor ploidy. Red, HPV genome detected; Blue, HPV genome not detected. (B) The presence of HPV is associated with polyploid karyotype in NECC. *, p < .05. (C) Map of gene-adjacent HPV integration events identified in NECC. Yellow, HPV16; Purple, HPV18.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0234505.g002