Cardiology Estimated pulse wave velocity as a forefront indicator of developing metabolic syndrome in Korean adults Hyun-Jin Kim, Byung Sik Kim, Dong Wook Kim, Jeong-Hun Shin Korean J Intern Med. 2024;39(4):612-624.   Published online June 24, 2024 DOI: https://doi.org/10.3904/kjim.2024.015                      Background/Aims: The predictive value of the estimated pulse wave velocity (ePWV) for the development of metabolic syndrome has not yet been extensively explored. This study aimed to fill this gap by evaluating ePWV as a potential predictor of metabolic syndrome development in middle-aged Korean adu..

Impact of an expanded reimbursement policy on utilization of implantable loop recorders in patients with cryptogenic stroke in Korea Hye Bin Gwag, Nak Gyeong Ko, Mihyeon Jin Korean J Intern Med. 2024;39(3):469-476.   Published online April 18, 2024 DOI: https://doi.org/10.3904/kjim.2023.479                      Background/Aims: The reimbursement policy for cryptogenic stroke (CS) was expanded in November 2018 from recurrent strokes to the first stroke episode. No reports have demonstrated whether this policy change has affected trends in implantable loop recorder (ILR) utilization. Methods: We identified ..

Modified application of SAMe-TT2R2 scoring system in Asian patients with atrial fibrillation for the selection of oral anticoagulants Seong Won Jeon, Nuri Lee, Ki Hong Lee, Minjeong Ha, Changhyun Kim, Yoo Ri Kim, Nam Sik Yoon, Hyung Wook Park Korean J Intern Med. 2024;39(3):458-468.   Published online January 30, 2024 DOI: https://doi.org/10.3904/kjim.2023.381                 Background/Aims: The SAMe-TT2R2 score is used for assessing anticoagulation control (AC) quality with warfarin. However, it is hard to apply SAMe-TT2R2 score in Asian patients with atrial fibrillation (AF), because it has not been proven in those populatio..

Association of epicardial adipose tissue with metabolic risk factors on cardiovascular outcomes: serial coronary computed tomography angiography study Sungjoon Park, Dong Eun Kim, Su Min Kim, JungMin Choi, Sang Joon Park, Hae-Young Lee, Eun Ju Chun Korean J Intern Med. 2024;39(2):283-294.   Published online February 14, 2024 DOI: https://doi.org/10.3904/kjim.2023.389                      Background/Aims: Epicardial adipose tissue (EAT) shares pathophysiological properties with other visceral fats and potentially triggers local inflammation. However, the association of EAT with cardiovascular disease (CVD) is still debatable. The study aimed to observe the changes and associations in..

Metabolic syndrome awareness in the general Korean population: results from a nationwide survey Hyun-Jin Kim, Mi-Seung Shin, Kyung-Hee Kim, Mi-Hyang Jung, Dong-Hyuk Cho, Ju-Hee Lee, Kwang Kon Koh Korean J Intern Med. 2024;39(2):272-282.   Published online January 30, 2024 DOI: https://doi.org/10.3904/kjim.2023.363                      Background/Aims: Metabolic syndrome (MetS) raises the risk of cardiovascular disease and type 2 diabetes. An awareness of MetS is vital for early detection and proactive management, which can mitigate the risks associated with MetS. Therefore, our study aimed to investigate the level of awareness of..

Sex differences in clinical characteristics and long-term outcome in patients with heart failure: data from the KorAHF registry Hyue Mee Kim, Hack-Lyoung Kim, Myung-A Kim, Hae-Young Lee, Jin Joo Park, Dong-Ju Choi; on the behalf of the KorAHF Investigators Korean J Intern Med. 2024;39(1):95-109.   Published online December 14, 2023 DOI: https://doi.org/10.3904/kjim.2023.288              Web of Science 1    Crossref 1                      Background/Aims: Sex differences in the prognosis of heart failure (HF) have yielded inconsistent results, and data from Asian populations are even rare. This study aimed to investigate sex differences in clinical characteristics and long-term prognosis among Korean patients with HF. Methods: A tot..

Time to presentation and mortality outcomes among patients with diabetes and acute myocardial infarction Min-A Shin, Seok Oh, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong Korean J Intern Med. 2024;39(1):110-122.   Published online December 11, 2023 DOI: https://doi.org/10.3904/kjim.2023.307              Crossref 1                      Background/Aims: Due to limited real-world evidence on the association between time to presentation (T2P) and outcomes following acute myocardial infarction and diabetes (AMI-DM), we investigated the characteristics of patients with AMI-DM and their outcomes based on their T2P. Methods: 4,455 patie..

Exercise capacity and risk of incident atrial fibrillation in healthy adults Ju Youn Kim, Soo Jin Cho, Juwon Kim, Tae-Wan Chung, Seung-Jung Park, Kyoung-Min Park, June Soo Kim, Young Keun On Korean J Intern Med. 2023;38(6):872-878.   Published online November 1, 2023 DOI: https://doi.org/10.3904/kjim.2023.075                 Background/Aims: Atrial fibrillation (AF) is a common arrhythmia and is associated with cardiovascular morbidity and mortality. It is important to identify and control the modifiable risk factors of AF. We aimed to examine the association of exercise capacity with the risk of incident AF within 3 ye..

Identification of novel variants for complicating cardiac disease in the scrub typhus infection using whole genome sequencing Ki-Woon Kang, Kyung-Won Hong, Seong-Kyu Lee Korean J Intern Med. 2023;38(6):865-871.   Published online November 1, 2023 DOI: https://doi.org/10.3904/kjim.2023.221                 Background/Aims: Scrub typhus infection has been known to complicate cardiovascular diseases mainly attributing to high mortality. Genetic susceptibility loci for complicating cardiac diseases such as atrial fibrillation, heart failure, and ischemic heart disease identified by genomic study have bee..

Clinical efficacy of angiotensin receptor-neprilysin inhibitor in de novo heart failure with reduced ejection fraction Su Yeong Park, Min Gyu Kong, Inki Moon, Hyun Woo Park, Hyung-Oh Choi, Hye Sun Seo, Yoon Haeng Cho, Nae-Hee Lee, Kwan Yong Lee, Ho-Jun Jang, Je Sang Kim, Ik Jun Choi, Jon Suh Korean J Intern Med. 2023;38(5):692-703.   Published online August 31, 2023 DOI: https://doi.org/10.3904/kjim.2023.065                 Background/Aims: We aimed to analyze the efficacy of angiotensin receptor-neprilysin inhibitor (ARNI) by the disease course of heart failure (HF). Methods: We evaluated 227 patients with HF in a multi-center retrospective cohort that included those with left ventricular ejection fraction (LVEF) ≤..

Clinical safety and effectiveness of the Genoss drug-eluting stent in real-world clinical practice Young Jin Youn, Jun-Won Lee, Sung Gyun Ahn, Seung-Hwan Lee, Junghan Yoon, Jae Hyoung Park, Sang-Yong Yoo, Woong Chol Kang, Nam Ho Lee, Ki Hwan Kwon, Joon Hyung Doh, Sang-Wook Lim, Yang Soo Jang, Dong Woon Jeon, Jung Ho Heo, Woong Gil Choi, Sungsoo Cho, Bong-Ki Lee, Hyonju Jeong, Bum-Kee Hong, Hyun-Hee Choi Korean J Intern Med. 2023;38(5):683-691.   Published online July 7, 2023 DOI: https://doi.org/10.3904/kjim.2023.129                      Background/Aims: The Genoss DES™ is a novel, biodegradable, polymer-coated, sirolimus-eluting stent with a cobalt- chromium stent platform and thin strut. Although the safety and effectiveness of this stent have been previously investigated, real-world clinical outcomes data are lacking. Therefore,..

Development and validation of equation for cardiorespiratory fitness in patients with heart failure with preserved ejection fraction Byambakhand Battumur, Ji Eun Lee, Soo Hyung Park, You-Jung Choi, Dong Oh Kang, Eun Jin Park, Ji Bak Kim, Jah Yeon Choi, Seung Young Roh, Jin Oh Na, Cheol Ung Choi, Jin Won Kim, Seung Woon Rha, Chang Gyu Park, Eung Ju Kim Korean J Intern Med. 2023;38(4):514-525.   Published online June 20, 2023 DOI: https://doi.org/10.3904/kjim.2022.375                      Background/Aims: Cardiorespiratory fitness (CRF), as measured by maximal oxygen consumption (VO2max), is an important independent predictive factor of cardiovascular outcomes in patients with heart failure (HF). However, it is unclear whether conventional equations for estimating CRF are applicable ..

Influence of an abnormal ankle-brachial index on ischemic and bleeding events in patients undergoing percutaneous coronary intervention Hangyul Kim, Seung Do Lee, Hyo Jin Lee, Hye Ree Kim, Kyehwan Kim, Jin-Sin Koh, Seok-Jae Hwang, Jin-Yong Hwang, Jong-Hwa Ahn, Yongwhi Park, Young-Hoon Jeong, Jeong Rang Park, Min Gyu Kang Korean J Intern Med. 2023;38(3):372-381.   Published online April 20, 2023 DOI: https://doi.org/10.3904/kjim.2022.348              Web of Science 2    Crossref 2                 Background/Aims: Bleeding events after percutaneous coronary intervention (PCI) have important prognostic implications. Data on the influence of an abnormal ankle-brachial index (ABI) on both ischemic and bleeding events in patients undergoing PCI are limited. Methods: We included patients who unde..

The role of discharge checklist in guideline-directed medical therapy for heart failure patients Helsi Rismiati, Kyu-Sun Lee, Jeehoon Kang, Hyun-Jai Cho, Hae-Young Lee Korean J Intern Med. 2023;38(2):195-206.   Published online February 21, 2023 DOI: https://doi.org/10.3904/kjim.2022.326              Web of Science 1    Crossref 1                      Background/Aims: Initiation of guideline-directed medical therapy (GDMT) during hospitalization is recommended for patients with heart failure (HF). However, GDMT is underutilized in real-world practice. This study evaluated the role of a discharge checklist on GDMT. Methods: This was a single-cent..

Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort Jin Young Lee, Jean Kyung Bak, Mina Kim, Ho-Gyun Shin, Kyun-Ik Park, Seung-Pyo Lee, Hee-Sun Lee, Ju-Yeun Lee, Kwang-il Kim, Si-Hyuck Kang, Jang Hoon Lee, Se Yong Jang, Ju-Hee Lee, Kye Hun Kim, Jae Yeong Cho, Jae-Hyeong Park, Sue K. Park, Hae-Young Lee Korean J Intern Med. 2023;38(1):56-67.   Published online December 14, 2022 DOI: https://doi.org/10.3904/kjim.2022.249              Crossref 4                      Background/Aims: This study evaluated the long-term cardiovascular complications among Korean patients with hypertension and compared them with that of controls without hypertension. Methods: The Korean Hypertension Cohort (KHC) enrolled 11,043 patients with hypertension and followed them for more ..

Treatment delay and outcomes of ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention during the COVID-19 era in South Korea Seok Oh, Myung Ho Jeong, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn Korean J Intern Med. 2022;37(4):786-799.   Published online June 28, 2022 DOI: https://doi.org/10.3904/kjim.2022.077              Web of Science 1                   Background/Aims: Little is known about the clinical characteristics and treatment outcomes of ST-segment elevation myocardial infarction (STEMI) in Korea during the coronavirus disease 2019 (COVID-19) era. We aimed to evaluate the clinical characteristics and treatment outcomes of patients with STEM..

Predictors of recurrent acute myocardial infarction despite successful percutaneous coronary intervention Sang Hun Lee, Myung Ho Jeong, Joon Ho Ahn, Dae Young Hyun, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Jin Yong Hwang, Weon Kim, Jong Seon Park, Chang-Hwan Yoon, Seung Ho Hur, Sang Rok Lee, Kwang Soo Cha; on behalf of the KAMIR (Korea Acute Myocardial Infarction Registry)-NIH Investigators Korean J Intern Med. 2022;37(4):777-785.   Published online June 28, 2022 DOI: https://doi.org/10.3904/kjim.2021.427              Web of Science 8    Crossref 6                      Background/Aims: Recurrent acute myocardial infarction (AMI) is an adverse cardiac event in patients with a first AMI. The predictors of recurrent AMI after the first AMI in patients who underwent successful percutaneous coronary intervention (PCI) have not been elucidated. Methods: We analyzed th..

Long-term outcomes in ST-elevation myocardial infarction patients treated according to hospital visit time Seok Oh, Dae Young Hyun, Kyung Hoon Cho, Ju Han Kim, Myung Ho Jeong Korean J Intern Med. 2022;37(3):605-617.   Published online November 16, 2021 DOI: https://doi.org/10.3904/kjim.2021.204              Web of Science 11    Crossref 10                      Background/Aims: Rapid percutaneous coronary intervention (PCI) is the cornerstone of treatment for ST-elevation myocardial infarction (STEMI). However, there have been conflicting results regarding the differences in clinical outcomes between on-hours and off-hours presentation in STEMI patients. W..

Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV Seok Oh, Ju Han Kim, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong Korean J Intern Med. 2022;37(3):591-604.   Published online April 28, 2022 DOI: https://doi.org/10.3904/kjim.2021.539                      Background/Aims: Acute myocardial infarction (AMI) is conventionally recognized as an urgent medical condition requiring timely and effective reperfusion therapy. However, the results of studies on the clinical outcomes in AMI according to hospital visit timings are inconclusive. To explore the differ..

The current status and outcomes of in-hospital P2Y12 receptor inhibitor switching in Korean patients with acute myocardial infarction Keun-Ho Park, Myung Ho Jeong, Hyun Kuk Kim, Young-Jae Ki, Sung Soo Kim, Youngkeun Ahn, Hyun Yi Kook, Hyo-Soo Kim, Hyeon Cheol Gwon, Ki Bae Seung, Seung Woon Rha, Shung Chull Chae, Chong Jin Kim, Kwang Soo Cha, Jong Seon Park, Jung Han Yoon, Jei Keon Chae, Seung Jae Joo, Dong-Joo Choi, Seung Ho Hur, In Whan Seong, Myeong Chan Cho, Doo Il Kim, Seok Kyu Oh, Tae Hoon Ahn, Jin Yong Hwang; on behalf of the KAMIR-NIH registry investigators Korean J Intern Med. 2022;37(2):350-365.   Published online January 12, 2022 DOI: https://doi.org/10.3904/kjim.2021.101              Web of Science 1    Crossref 1                      Background/Aims: While switching strategies of P2Y12 receptor inhibitors (RIs) have sometimes been used in acute myocardial infarction (AMI) patients, the current status of in-hospital P2Y12RI switching remains unknown. Methods: Overall, 8,476 AMI patients who underwent successful revascularization..