The developmental disruptions of serotonin signaling may involved in autism during early brain development

CJ Yang, HP Tan, YJ Du�- Neuroscience, 2014 - Elsevier
Autism is a developmental disorder defined by the presence of a triad of communication,
social and stereo typical behavioral characteristics with onset before 3 years of age. In spite�…

Autism genetics–an overview

J Yin, CP Schaaf�- Prenatal diagnosis, 2017 - Wiley Online Library
Autism spectrum disorder (ASD) is a highly heritable, clinically diverse group of
neurodevelopmental disorders. Its genetic heterogeneity is remarkable, with more than 800�…

[BOOK][B] The neuroscience of autism spectrum disorders

JD Buxbaum, PR Hof - 2012 - books.google.com
Autism is no longer considered a rare disease, and the Center for Disease Control now
estimates that upwards of 730,000 children in the US struggle with this isolating brain�…

[HTML][HTML] Translational approaches to the biology of Autism: false dawn or a new era?

C Ecker, W Spooren, DGM Murphy�- Molecular psychiatry, 2013 - nature.com
Discovering novel treatments for Autism Spectrum Disorders (ASD) is a challenge. Its
etiology and pathology remain largely unknown, the condition shows wide clinical diversity�…

[HTML][HTML] Getting to the cores of autism

LM Iakoucheva, AR Muotri, J Sebat�- Cell, 2019 - cell.com
The genetic architecture of autism spectrum disorder (ASD) is itself a diverse allelic
spectrum that consists of rare de novo or inherited variants in hundreds of genes and�…

[HTML][HTML] The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models

L Mapelli, T Soda, E D'Angelo, F Prestori�- International journal of�…, 2022 - mdpi.com
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and�…

A dopamine hypothesis of autism spectrum disorder

D Pavăl�- Developmental neuroscience, 2017 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. While several theories have�…

Communication, interventions, and scientific advances in autism: a commentary

DC Llaneza, SV DeLuke, M Batista, JN Crawley…�- Physiology &�…, 2010 - Elsevier
Autism spectrum disorders (ASD) affect approximately 1 in 150 children across the US, and
are characterized by abnormal social actions, language difficulties, repetitive or restrictive�…

Regulatory genes and pathways disrupted in autism spectrum disorders

F Ayhan, G Konopka�- Progress in Neuro-Psychopharmacology and�…, 2019 - Elsevier
Autism spectrum disorder (ASD) is a highly prevalent and complex genetic disorder. The
complex genetic make-up of ASD has been extensively studied and both common and rare�…

[HTML][HTML] Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga…�- Signal transduction and�…, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known�…