A dopamine hypothesis of autism spectrum disorder

D Pavăl�- Developmental neuroscience, 2017 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. While several theories have�…

The dopamine hypothesis of autism spectrum disorder revisited: current status and future prospects

D Pavăl, IV Micluția�- Developmental neuroscience, 2021 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. Despite intensive research, its�…

[HTML][HTML] Dopaminergic dysregulation in syndromic autism spectrum disorders: insights from genetic mouse models

P Kosillo, HS Bateup�- Frontiers in Neural Circuits, 2021 - frontiersin.org
Autism spectrum disorder (ASD) is a neurodevelopmental disorder defined by altered social
interaction and communication, and repetitive, restricted, inflexible behaviors. Approximately�…

Behavioral neuroscience of autism

T Takumi, K Tamada, F Hatanaka, N Nakai…�- …�& Biobehavioral Reviews, 2020 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder. Several genetic causes
of ASD have been identified and this has enabled researchers to construct mouse models�…

Excessive D1 dopamine receptor activation in the dorsal striatum promotes autistic-like behaviors

Y Lee, H Kim, JE Kim, JY Park, J Choi, JE Lee…�- Molecular�…, 2018 - Springer
The dopamine system has been characterized in motor function, goal-directed behaviors,
and rewards. Recent studies recognize various dopamine system genes as being�…

[HTML][HTML] Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors

GE DiCarlo, JI Aguilar, HJG Matthies…�- The Journal of�…, 2020 - Am Soc Clin Investig
The precise regulation of synaptic dopamine (DA) content by the DA transporter (DAT)
ensures the phasic nature of the DA signal, which underlies the ability of DA to encode�…

[HTML][HTML] Striatal circuits as a common node for autism pathophysiology

MV Fuccillo�- Frontiers in neuroscience, 2016 - frontiersin.org
Autism spectrum disorders (ASD) are characterized by two seemingly unrelated symptom
domains—deficits in social interactions and restrictive, repetitive patterns of behavioral�…

Neurobiological correlates of social functioning in autism

E Neuhaus, TP Beauchaine, R Bernier�- Clinical psychology review, 2010 - Elsevier
Although autism is defined by deficits in three areas of functioning (social, communicative,
and behavioral), impairments in social interest and restricted behavioral repertoires are�…

The neurobiological context of autism

F Keller, AM Persico�- Molecular neurobiology, 2003 - Springer
Autistic disorder (AD) is a complex neuropsychiatric disorder of neurodevelopmental origin,
where multiple genetic and environmental factors may interact, resulting in a clinical�…

Decoding the contribution of dopaminergic genes and pathways to autism spectrum disorder (ASD)

M Nguyen, A Roth, EJ Kyzar, MK Poudel…�- Neurochemistry�…, 2014 - Elsevier
Autism spectrum disorder (ASD) is a debilitating brain illness causing social deficits, delayed
development and repetitive behaviors. ASD is a heritable neurodevelopmental disorder with�…