Digital strategy and social media have profound potential to inform health formation dissemination with their broad reach and can be used in the field of infectious diseases to further patient advocacy, clinical care, education, professional development, and combat misinformation. At the center of this image is the representation of vaccination, which has represented a critical source of scientific innovation, clinical triumph, conflict, misinformation, and fracture. During the pandemic, the rapid dissemination of information has caused a critical need for high-quality expertise and data analysis to be provided by trustworthy sources and elevated the need for individuals with expertise in infectious diseases to be sources of information and trust. Social media and digital strategies can be used to collect data and disseminate primary data, to serve as a platform and a megaphone to disseminate guidance, to distill evidence and share knowledge, and to allow for mentoring and the creation of networks for individuals and groups to connect over broad geographical reach. (Cover illustration by Ni-Ka Ford, Icahn School of Medicine at Mount Sinai). @NikaFord_ (Twitter)