Assesssment and management of Guillain-Barré syndrome in the context of Zika virus infection: interim guidance update
Overview
On 1 February 2016, the Director-General of the World Health Organization (WHO) declared the recent clusters of microcephaly cases, Guillain-Barré syndrome (GBS) and other neurological conditions in some areas affected by Zika virus, a Public Health Emergency of International Concern.
As of 07 July 2016, fifteen countries and territories worldwide have reported increased GBS incidence and/or laboratory confirmation of Zika virus infection among people with GBS. Other neurological manifestations, including myelitis (inflammation of the spinal cord), meningoencephalitis (inflammation of the brain and meninges) and acute disseminated encephalomyelitis (ADEM) have been identified in patients with Zika virus infection, however, further work is required to understand the spectrum and impact of such manifestations in the context of Zika virus infection.
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