A diverse multicultural city of almost 1.3 million, Panama City offers a lot more than an up-close view of the Canal. Shantytowns slink up alongside shiny high-rise condos. The Old City is an atmospheric labyrinth of churches, plazas and palaces. Fifteen miles from downtown Panama City, Soberania National Park is an excellent destination for hiking and birding. For a fascinating look at the canal, take a taxi or local bus to Miraflores Locks Visitor Center and look down on the traffic below.

Like seashells, no two holidays in the Bahamas are alike. With options as diverse as its 700 islands, it's a place where you can find exactly the getaway you love most. Looking for a family destination, a place for lovers to sneak away, a gambling mecca, a haven for cruise passengers, or a shopper’s world market? The Bahamas is all these… and much more.

Stretching 126 miles south toward Cuba, the stunning Keys are a perfect escape. Highlights along the way include Key Largo, Islamorada, Marathon, Big Pine Key and the irrepressible Key West. Get up close with an amazing array of fish while snorkeling, diving or fishing in the warm turquoise waters. Creeks, coral and costumed spectacles are other lures along the way. Highway 1 is a spectacular ribbon tying together the islands and atolls of this paradise between the Gulf of Mexico and the Atlantic.

Since the redevelopment of the Inner Harbor in the late 1970s, Baltimore has set the standard for urban renewal. While a good part of the city's action centers around the fun and festive Harbor area, where street entertainers, open-air concerts, fireworks and parades abound, the surrounding neighborhoods offer all sorts of interesting landmarks, unique shops and delicious restaurants. Wander around Fells Point, the oldest section of Baltimore, reminiscent of an old English village, complete with pubs and cobblestone streets. Take the kids to the aquarium and check out the imaginative creations at the American Visionary Art Museum. Or stop by the Babe Ruth Birthplace and Museum for an in-depth look at the Great Bambino's life. Baltimore is also renowned for its African-American heritage sites, plus festivals and cultural events that take place throughout the year. From historic places and harbor cruises to family friendly attractions and fabulous neighborhoods, Charm City is one of the top tourist destinations in the United States.

Located on the shores of Lake Michigan, Milwaukee is perhaps best known for its famous breweries and the Major League Brewers, but there's more to the city than beer and baseball. Milwaukee is rich in historical and cultural attractions, making it the perfect place for a weekend of exploring. Check out the newly expanded Milwaukee Art Museum or the Mitchell Park Horticultural Society, which hosts an annual show of the same flora and fauna seen in Georgia O'Keefe's paintings. Those interested in the city's history can visit the grand Pabst Mansion, former home of one of the city's famous beer barons, or the Milwaukee Public Museum, to see what life was like in Old Milwaukee. If the kids are along, don't miss the Milwaukee County Zoo or the Betty Brinn Children's Museum. Of course a trip to the "Genuine American City" would not be complete without a tour of the Miller Brewing Company and a Brewers game at Miller Park.

Shaped by the currents and curves of the Wisconsin River, Wisconsin Dells has been a favorite family vacation destination for more than 150 years. An explosion of indoor water parks has turned the Dells from a summer hot spot to a year-round destination. Kids will enjoy the seemingly endless supply of fun and games, from go-karts to miniature golf, sideshows to thrill rides. If the weather's right, you can take a Duck tour of land and water, and top it all off with a heaping helping of the local fudge.

Strolling, shopping, and sipping tequila along the Malecon boardwalk of Puerto Vallarta is the best way to kick off your vacation. Then hit the cobblestone streets of Old Vallarta to browse the flea market for handmade crafts. The calm, warm waters of the Bay of Banderas make for excellent diving, or you can just watch artists sculpt spectacular creations in the sand. The cluster of fine art galleries in El Centro are perfect spots to hit on a self-guided art tour.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.

Located in the South Pacific more than 2,000 miles off the Chilean coast, Easter Island’s not the easiest place to reach. (If you’re interested, the easiest access is by air from Santiago or Tahiti.) But isolation has helped preserve the 1,500-year-old mysterious congregation of volcanic rock sculptures (maoi) that’s the island’s biggest claim to fame. After exploring the unique landscape, relax on an uncrowded beach and ponder one of the most mysterious places on Earth.