Whether you’re a high roller or a low-key lounger, Las Vegas has something to suit your vacation taste. Sample fare from top chefs and cornucopian buffets, try your luck at one of the world’s premier casinos, or take in a spectacular show. Just wandering the Strip is enough to get your heart pumping. Once you’ve had enough of the razzle-dazzle, wave hello to the toothy sea life at the Mandalay Bay Shark Reef, hike Red Rock Canyon, or visit the Neon Museum, where old signs take on new life.

Looking to relax in the sun? Palm Springs, with 354 days of sunshine per year, might be the place for you. Relax poolside or visit one of the many area spas… or tour some fantastic examples of mid-century modern architecture.

Sedona is a true oasis, a vacationer’s paradise in the middle of the Arizona desert. Here, you’ll find resorts and spas, canyons and red rock formations. Bell Rock and Oak Creek Canyon are great hiking spots, and the dramatic architecture of the Chapel of the Holy Cross is a religious experience itself. When the sun dips down below the horizon it introduces the best show in Sedona: the night sky.

Scottsdale has more spas per capita than any other city in the U.S.—so whether you’re looking for the latest medi-spa technology or a new-agey, bohemian vibe, there’s sure to be something for you. It's a good thing, too—after spending all day touring the beautiful desert, you'll be grateful for some pampering.

Although Tucson's fantastic weather, national parks and forests and desert provide the perfect environment for tons of outdoor recreational activities, this city of half a million people also has its share of history and culture. With a history that goes back much further than many of its southwestern neighbors, Tucson boasts turn-of-the-century architecture, historic neighborhoods, museums and the Mission San Xavier del Bac, a still-functioning 18th-century mission considered one of the most beautiful in the U.S. Mexican and Native American influences are pervasive, and the city has a distinctly Western flavor. There's also a college-town atmosphere, thanks to the University of Arizona, which has its own share of museums and a science center. Whether golfing at a world-class golf resort, horseback riding, hiking in the wilderness, discovering desert flora and fauna at the Arizona-Sonora Desert Museum or exploring pre-Columbian and other art at the Tucson Art Museum, you'll have a mind-boggling array of things to do.

Mesa is a thriving metropolis in the southwest, with lifestyle and leisure pursuits in high demand by visitors. Surrounded by the Sonoran Desert, Mesa is a playground for outdoor recreation, with convenient access to three lakes, two rivers and endless hiking trails. The city’s downtown is a vibrant epicenter with boutiques, antique shops, museums, studios and cafes – all anchored by Mesa Arts Center. Mesa is home to a stunning collection of golf courses, superb dining and upscale shopping.

Hit the casinos, watch big-name entertainment and stay at a themed hotel. Las Vegas? No, but this small gambling town on the banks of the Colorado River offers a taste of Vegas minus the glitz, traffic and high costs. Plus, there's much to do here besides gambling. Not only does Laughlin have the Colorado River for boating, swimming, fishing, waterskiing and other sports, but it also has gorgeous Lake Mohave offering much of the same on a grander scale. Golfers will enjoy beautiful courses where reasonable green fees stretch their dollars. For a taste of the Wild West, head to nearby 100-year-old Oatman, where you can catch a mock gunfight and guzzle beer in an old-time saloon. Hiking, anyone? Grapevine Canyon awaits you, famous for the Indian markings - some 800 years old - carved into its boulders. If the slots are calling, you'll find plenty of gaming houses, with water shuttles running between them 24/7. What Laughlin lacks in Vegas glamour, it makes up for in affordability, scenic beauty and aquatic fun.

Relax and sight-see in this southern Californian oasis. Located in the center of the Coachella Valley, Palm Desert is a vibrant city featuring top notch resorts, world class golfing, shopping, and entertainment that appeals to many types of consumers. Hike, bike or ride horseback through the desert trails. Or, soak in some culture with seasonal festivals, stylish art galleries, and a thriving music and nightlife scene.

Desert meets sea in Puerto Penasco, a California Gulf getaway. With its seafood markets, snoozy streets, and sandy beaches, it's easy to see how the port town has retained its traditional charm. There's something for everyone, from nature parks and water sports to upscale resorts.

Shimmering Lake Havasu, the centerpoint of Lake Havasu City, was formed in 1938 after the Parker Dam was built. It is perhaps most famous for the London Bridge that looms above it. Yes, the actual London Bridge, bought by the area's founding father, Robert McCullough, for $2,460,000, after the city of London put it up for auction in 1968. Today, Lake Havasu City is one of the most popular vacation destinations in Arizona and offers a range of recreational activities for families, couples and single travelers. Golf on championship courses, soak up the sun on the shores of Lake Havasu's beaches or explore nearby parks by foot and bicycle. Houseboats dot the lake and are available for rent along with paddle boats, kayaks, jet skis and other types of water sports equipment. Like most resort towns Lake Havasu is chock-full of hotels, restaurants, shops and non-stop action.

Not just for retirees and theme park enthusiasts, the Sunshine State offers beautiful beaches, pristine diving conditions, and sizzling nightlife. Salsa the night away in a smokin’ hot Miami club, or swing away at one of Kissimmee’s many premium golf courses. An airboat tour of the Everglades is an unforgettable adventure – just look out for alligators! For the risk-averse, a lazy day spent on the soft sands of an Emerald Coast beach is as rejuvenating as a spa treatment.

New York State has it all – booming metropolises, majestic waterfalls, mountains, wine country, chicken wings. Yes, NYC is a magnet for tourists, but an exploration of the rest of the state can be equally thrilling. The Finger Lakes Wine Region is a vision of serene waters, quaint B&Bs, and pretty vineyards. Movie buffs will love Rochester, home of the George Eastman House and one of the world’s most comprehensive film archives. On your way to Niagara Falls, stop in Buffalo to fuel up on spicy wings.

North Carolina has something for everyone, with the highest mountains in the eastern U.S., 300 miles of pristine coastline, quaint towns and vibrant cities. From the mountains to the sea, explore the natural, scenic beauty, discover outdoor adventure or try one of 500 golf courses, including the legendary Pinehurst No. 2. Discover a favorite among 100 wineries and 60 craft breweries, tour historic and cultural treasures, sample farm to table delicacies and get the thrill of motorsports in the "home" of NASCAR.

California is a fertile, peaceful place where you’ll find a near-equal balance of vineyards and deserts, beaches and mountains, hippies and traditionalists. Catch an epic wave in Big Sur or swirl a glass in Napa Valley. Be dazzled by the Joshua Tree night sky or just star-gaze in Hollywood. Swish down the slopes of a Tahoe ski resort, or cruise across the Golden Gate Bridge with the top down and the music blasting. Above all, don’t forget to soak up some Golden State sunshine.

If you are looking for an active place to stay with world-class attractions, Ohio’s major cities can satisfy any vacation desire. Each offers its own distinct flavor of fun, from professional sports – Bengals (Cincinnati), Cavaliers (Cleveland) and Indians (Cleveland again) – to museums, outdoor activities and more. One of the most famous is the Rock and Roll Hall of Fame in Cleveland. If football is your thing, don’t miss the Pro Football Hall of Fame in Canton. For the science-minded, visit the meat eaters at the Carnivore Conservation Center in the Wilds near Cambridge, dedicated to the breeding and scientific study of endangered mid-sized carnivores. Kids will also love Planet Snoopy in Sandusky or the Columbus Zoo’s Zoombezi Bay Waterpark and Jack’s Landing rides.

From the riverboat casinos, breweries and historical neighborhoods in St. Louis and fabulous fountains and barbeque in Kansas City to the “Live Music Show Capital of the World, Branson, to the awesome outdoor lifestyle in the Lake of the Ozarks region, the state offers visitors a seemingly endless line-up of unique vacation experiences. You’re never far from a state park or historic site as there are 85 of them throughout the state. There are 840 miles of trail for hikers, backpackers, bicycle riders, off-road vehicle users and horseback riders. Some of the state’s top attractions include the Gateway Arch and St. Louis Zoo in St. Louis, Cameron Cave in Hannibal, and the American Jazz Museum and Worlds of Fun amusement park in Kansas City. Wine lovers will be pleased to know there are 96 wineries in the state where you can sample wines and take tours. For golfers, the picturesque Lake Ozark region offers play on gems like the Tan-Tar-A Resort Oaks Course and Old Kinderhook. Why not introduce your children to the real world of Tom Sawyer and Huck Finn? Visit Hannibal, where your kids can immerse themselves in the world of Mark Twain with a tour of the author’s home, a cruise on the Mississippi River, an exploration excursion of the caves in his books and visits to various historic homes. Other great family-oriented activities throughout the state include hiking the Ozark Trail, splashing at a water park in Branson and visiting the Harry S. Truman home and presidential library in Independence.

Think you need an ocean for a beach? Think again. There are miles and miles of sandy lakefront beaches in Michigan (thanks to the four Great Lakes that border it). The west coast of Michigan has especially nice beaches—try a rental in Muskegon, Grand Haven or Saugatuck. You won’t need a car when visiting Mackinac Island. In fact, they’re not allowed—this lovely Victorian resort town is pedestrian-only.

Stretching 126 miles south toward Cuba, the stunning Keys are a perfect escape. Highlights along the way include Key Largo, Islamorada, Marathon, Big Pine Key and the irrepressible Key West. Get up close with an amazing array of fish while snorkeling, diving or fishing in the warm turquoise waters. Creeks, coral and costumed spectacles are other lures along the way. Highway 1 is a spectacular ribbon tying together the islands and atolls of this paradise between the Gulf of Mexico and the Atlantic.