The name says it all: Belo Horizonte, or “beautiful horizon,” has stunning views of surrounding mountains. Built as a planned city about a century ago, its tree-lined streets are laid out in a tidy grid. Explore the modern Brazilian architecture of the Pampulha neighborhood, relax in Mangabeiras Park or indulge in some epic retail therapy. Refresh with a cachaça rum cocktail, or tuck into a sumptuous pile of meat at a traditional Brazilian barbecue restaurant.

German-inspired architecture adds a quirky Alpine twist to this resort, where high-altitude pine forests offer a wonderfully cool escape from the lowland heat. Add emerald-green peaks as a backdrop, and Campos do Jordao becomes a tropical mountain stunner.

If there’s a "beach economy," Buzios is its Wall Street. Its more than 20 beaches, world-class galleries, clubs and boutiques draw an elite set of travelers. Surfers love Geriba Beach, snorkelers enjoy Ferruda, hip Ossos Beach offers upscale beachside cafes and laid-back Ilhabela Beach offers a more down-to-earth Buzios experience.

The largest game reserve in South Africa, Kruger National Park is basically a synonym for the word "safari." Home to over 500 bird species, 100 reptiles, nearly 150 mammals, multiple archaeological sites, and a stunningly diversity of trees and flowers, Kruger is the country’s flagship national park. Adventurers can explore the park in a 4x4, take a bush walk or fly above in a hot-air balloon.

Just north of Cancun, this seaside resort community is a far cry from the spring-break crowd. Bordered on one side by the Mexican Caribbean and the other by a wetlands wildlife preserve, the vibe in Playa Mujeres is one of laid-back luxury in a natural, untouched landscape. Unlike many other such tranquil places, Playa Mujeres is not a pain to get to. It's an easy ride from Cancun airport.

Once a sleepy fishing village, Placencia has emerged as an increasingly popular eco-destination on the Caribbean. For those who enjoy outdoor adventure, the Stann Creek region offers a host of activities: hiking through mountainous rain forests, kayaking, deep sea fishing, diving and exploring Mayan ruins. The peninsula boasts 16 miles of tranquil beaches, with a lagoon to the west and the Caribbean to the east and lots of peace and quiet in the middle. Tour guides and dive centers offer a variety of excursions, with boat rides to the outer cayes an ongoing favorite. Also popular are guided land tours to Mayan Ruins or trekking the jungle trails of Cockscomb Basin Wildlife Sanctuary, where the first Jaguar Reserve in the world was established.

With miles of sandy coastline, it’s no surprise that Fuengirola is a major draw on Spain's Costa del Sol. But the resort town offers than just beaches—a Moorish castle, immersive bio-zoo, amusement parks, and retail zone provide entertainment for the whole family.

Whether rocking out to music legends inside the Rock and Roll Hall of Fame or viewing Monets and Picassos at the Cleveland Museum of Art, Cleveland is a city that mixes equal parts grit and sophistication. Nosh award-winning food in historic buildings, tip back some craft beers amid a Lake Erie beach party or cheer on a championship team with a hardball of locally distilled spirits. All in Cleveland.