Avignon charms visitors with its ancient streets, restored medieval ramparts and the immense Gothic architecture of the Palais des Papes (Palace of Popes—the papacy was based here in the 14th century). The annual Festival d'Avignon, a major arts festival, attracts hundreds of thousands of visitors for theater, dance, film and street performances.

In the chic, sun-drenched Costa del Sol town of Marbella, hints of its former Moorish occupation mingle with modern-day resort amenities. Bask on the sands of famous La Fontanilla beach or ricochet among the area's family-oriented water, wildlife and theme parks. Experience the Andalusian charm of the historic quarter, filled with whitewashed buildings, remnants of a ninth-century Arab fortress and fragrant orange trees. End a relaxing day with a dish of the cold almond soup ajoblanco and some of the region's excellent dessert wine.

A captivating contrast of old and new, Luxembourg City's past is celebrated by its World Heritage status; its present sway by its position as headquarters for several significant European institutions. Small enough to explore on foot, this compact city offers a wealth of attractions, including dramatic promontory The Bock, underground passages in Petrusse Casemates, Palace of the Grand Dukes and the National Museum. Countless banks on Boulevard Royal, once a fortress moat, hint at the duchy's wealth.

This big resort—the largest on Gran Canaria—was developed in the 1960s specifically as a tourist area. And all types of tourists have found it. LGBT travelers, families with kids, au naturel sunbathers, honeymooners, groups of young singles… there’s a spot for everybody on the beach here (and a hotel or apartment for every budget).

Home to sprawling beaches, retail centers, and activity parks, the resort town of Puerto Rico is one Gran Canaria’s more family-friendly destinations. Subtropical temperatures and sunny skies make an ideal climate to soak up rays on golden sands or explore the volanic coast.

Quebec City may be the only fortified city north of Mexico, but it welcomes visitors with open arms. Explore the Citadel, where you might catch Canadian troops staging a military ceremony. As for food, you could splurge on afternoon tea at the Chateau Frontenac, or do as the locals do and snack on poutine—french fries with gravy and cheese curds.

With an average of 320 days of Florida sunshine each year – and 27 miles of sugar-white sands bordering the clear, emerald green waters where the Gulf of Mexico and St. Andrew Bay converge – Panama City Beach is a favorite of travelers seeking an affordable beach vacation with year round offerings. The region also features exciting on- and off-shore attractions, including St. Andrews Park and Pier Park, that offer something special to adrenaline-seekers, eco-tourists, families and couples alike.