Lively nightclubs pulsing with Caribbean beats drive the nightlife scene of Cabarate, a breathtaking beach town. Not even the stubbornly two-left-footed can keep their toes from tapping when the sun goes down on Cabarete, which brims with culture and energy. Beachfront bars cum discotheques are the perfect spot to shake what your Mami gave you.

Located on the northeastern coast of the Samana Peninsula, Las Terrenas offers miles of protected inshore waters and beautiful, undeveloped white-sand-beaches, lined with tall palm trees and pastel-colored fishing boats. Trade winds and the warm temperature of the sub-tropical Atlantic Ocean bring this part of the island year-round balmy weather. With a year-round average of 77 degrees Fahrenheit, the temperatures vary only 18 degrees between summer and winter.

The ideal destination for families, honeymooners, divers and golfers alike, La Romana is home to the famous Casa de Campo resort, internationally renowned golf courses, a world-class marina and Altos de Chavón, a beautiful replica of a 16th-century artisan village. Nearby, the Bayahibe area offers picturesque beaches, chic accommodations, desirable attractions and splendid opportunities for ecotourism. Visitors can enjoy stunning Saona Island, Cotubanamá National Park and more.

There's more than one way to enjoy the spa experience in St. Lucia. One is to book a treatment at any of the luxury spas or resorts on the island. The other is to visit Sulphur Springs, inside the bowl of an extinct volcano, where you're welcome to try a volcanic mud bath or the 31°C/88°F Roman bath.

Greenville, South Carolina, is a welcoming place to shop, dine, see historic homes and watch minor-league sports. The city is also home to significant art collections and a vibrant performing-arts scene. Families can enjoy child-friendly activities such as searching for nine bronze mice scattered around the city, visiting the Greenville Zoo, relaxing in the many outdoor spaces and enjoying numerous annual festivals. State parks and Revolutionary and Civil War sites are a short drive away.

You'll find crashing waves off Cabo's Pacific coast and sheltered, calm water on the Sea of Cortez. Given those options, Cabo has built a rare reputation for both excellent outdoor sports (big-game fishing, diving and kayaking, among others) and pure beach relaxation. Of course, there's also great nightlife. Cabo’s resorts, hotels and inns cater to everyone from honeymooners to families to Hollywood stars seeking a weekend getaway.

With the bluest of blue water and the greenest of green surrounding forest, Lake Tahoe, quite simply, transfixes. From the early Indians to authors such as Mark Twain, people have tried to capture the beauty and mystique of the lake with nicknames like "Big Blue" and "Grasshopper Soup". Others maintain that it's impossible to describe the magnificence in words. At 6225 feet above sea level, Tahoe is the highest alpine lake in the United States and has long attracted holidaymakers from around the world. In the summer, hiking, windsurfing, golfing, fishing and swimming (usually in wet suits due to the lake's brisk year-round temperature) are all the rage. The winter season starts in late November, around Thanksgiving, and brings throngs of skiers to local resorts. Located between California and Nevada, different sides of the lake tend to attract different types of visitors. The California side draws families and outdoor enthusiasts while the Nevada side beckons those looking for big-name entertainment and casinos. No matter which side you choose, a getaway to stunning Lake Tahoe will not soon be forgotten.

Nevada's "other" gambling and resort town, Reno is located in the western part of the state near the California border. What the city lacks in glitz or reputation it more than makes up for in attractions and amenities. There are first-rate hotels, golf courses and casinos to rival its southern counterpart and, also like Las Vegas, Reno has become a popular destination for families. Galena Creek Park offers nature trails that even young children can navigate, plus organised educational events for families.

With its ideal location on the magnificently rugged Oregon Coast, the entire city of Newport is a natural observatory that offers a number of fun and educational activities for the whole family. Spend the morning exploring tide pools, combing the beach for fossils and spotting marine life in their natural habitats. Then head over to the Oregon Coast Aquarium where you can pet an octopus and walk through a glass tunnel surrounded by sharks. Newport is also home to two lighthouses, one of which is the tallest on the Oregon Coast. Historic Nye Beach, with its colorful cottages and laid-back atmosphere, is the perfect spot for a picnic and a quick rest from all the sightseeing.

As the first place in Spain to see the sunrise, Minorca is like the country’s ambassador to the morning. Beaches here are beautiful and, surprisingly, relatively empty. The jewel-coloured water is a magnet for waterskiers, windsurfers and sailors. Playa De Binigaus beach is perfect for families, while Cala Mitjana is an idyllic spot for romance. Head to the town of Alaoir to nibble on some fresh local cheese or turn back time in the charming fishing village of Fornells.

Located on the Rhine River near the borders of France and Germany, Basel contains the country's highest concentration of museums. The culture-centric city, site of the world's most influential art market each June, is also home to the lovely Munster Cathedral, made of red sandstone with a multi-colored tile roof. Green spaces abound, including the popular zoological gardens in the city center. Switzerland's largest site of Roman ruins, Augusta Raurica, are an easy day trip to the east.