Distinctive architecture, sun-drenched resorts and eclectic small towns dot Andalusia, a dry, mountainous region of southern Spain that maintains echoes of its Moorish occupation. Spring and fall bring balmy temperatures, ideal for visiting Seville's cathedral, the world's largest Gothic structure, and the 1200-year-old mosque in Córdoba. Romantics love Granada, home to the Alhambra fortress and an inspiration to the late poet Federico García Lorca. Don't miss a dip in the sea along the Costa del Sol.

The small city of Sitges parties big. The nightlife is thumping, the people are gorgeous and the annual Carnival festival is utterly epic. A countercultural touchstone, Sitges is lively and very LGBT friendly. Native food and beverage is sublime—you simply must sample the Malvasia wine, made from grapes descending from Ancient Greece. Don’t miss the Museu Romàntic "Can Llopis" or, if you’re in Sitges in October, the world-renowned Sitges Film Festival, a cinematic extravaganza of horror, sci-fi and fantasy.

One of southeastern Sicily’s UNESCO-listed baroque cities, Noto is famed for its opulent architecture and surfeit of beauty. Its 18th-century cathedral is a local highlight, as is Caffe Sicilia, which is rumored to make some of the best gelato in all of Italy.

The sun-drenched Canary Islands lie close to North Africa and have an exotic flavour of their own. Hundreds of volcanoes, rolling sand dunes, rich forests and rugged cliffs dapple these seven Atlantic gems. Catch a ferry to Lanzarote. Ride a camel through volcanic Timanfaya National Park. Take on Tenerife, home of Mount Teide, Spain's tallest peak. Romp Grand Canary's beaches or hike La Gomera's Garajonay National Park. More adventures await on tiny El Hierro, verdant La Palma and peaceful Fuerteventura.

The Baroque Palace of Oradea is simply epic. Now a museum, the 18th-century building is home to an outdoor bronze and marble statue park, Transylvanian folk art and a collection of animal remains that includes dinosaur fossils. You could spend days here, but try to make some time for other Oradea attractions, such as the beautiful Art Nouveau buildings of Str. Republicii, the astronomical clock of the Biserica cu Lună, and the Băile Felix thermal spa.

Featuring white-sand beaches, volcanic peaks, and protected parks, along with some of the most impressive dive spots in the world, Guadeloupe is an island hopper’s paradise. This French archipelago is one of the Caribbean's best-kept secrets, offering a more relaxed alternative to its better-known neighbours.

We won't lie: Niagara Falls is uber-touristy. There are wax museums and a Ripley's Believe It or Not Museum, and if it's a fast-food chain, you can probably find it here. But even the most jaded hipster shouldn't pass up a chance to visit this town, because the Falls themselves are spectacular.