Reading can justify a general 5-4 quote to beat visitors West Brom in their FA Cup third round replay on Tuesday evening. The first game ended 1-1.
The Royals continued their relentless progress towards a place in the top flight next season when they polished off Coventry 2-0 over the weekend, and they are now nine points clear of second-placed Sheffield United in the Coca-Cola Championship.
West Brom, of the Barclays Premiership, also come into the match on the back of a valuable win, in their case a 1-0 victory over Wigan on Sunday.
That was a hard-fought win for them, though, after being reduced to ten men with the sending off of Darren Moore just before half-time.
The Baggies have had just 48 hours to recover, and are further hindered by the loss of the suspended Moore for this match. Expect Reading to take advantage.
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The two non-League sides in action are likely to reach the end of the road. Middlesbrough, despite a fearful drubbing at the hands of Arsenal on Saturday, have the perfect opportunity against visitors Nuneaton, although odds of 1-8 with Ladbrokes reflect that.
Stoke should make amends for being held at home by Tamworth and are difficult to oppose at 8-13, also with Ladbrokes.