Complement system

Complement System Pathways Diagram #Immunology #Immuno #Medschool #medicalschool #medicalstudent #study #studyguide #studymaterial #Innate #Adaptive #MBL #ClassicPathway #AlternativePathway

Classical pathway : Here complement system is activated by antibodies bound to pathogen surface or antibody-antigen complexes, thus involv...

Complement System The complement system, specifically through the actions of proteins C3a and C3b, destroys microbes. – Comprises inactive proteins that circulate in the blood; of these proteins, the products of C3 cleavage (C3a and C3b) have multifold functions. • Three pathways lead to C3 cleavage: – In the classical pathway, C1 is "fixed" to antibody-antigen complexes, which initiates a cascade of events that lead to C3 cleavage. – The alternative pathway is triggered by spontaneously…

The early events of all three pathways of complement activation involve a series of cleavage reactions that culminate in the formation of an enzymatic activity called a C3 convertase, which cleaves complement component C3 into C3b and C3a. The production of the C3 convertase is the point at which the three pathways converge and the main effector functions of complement are generated. C3b binds covalently to the bacterial cell membrane and opsonizes the bacteria, enabling phagocytes to…

Complement system consists of approximately 20 serum proteins that interact with each other and other components of immune system to elimin...

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Individuals with a complement deficiency can have clinical problems that are a result of the role that the specific complement protein plays in the normal function of the human body.

An illustrated guide to the cells of the immune system and the components of the normal immune response, complete with a super helpful summary diagram

The complement pathways is a part of the innate immune system and consists of a series of proteins that interact with one another.