Publishing in Nature, University of North Carolina School of Medicine researchers and colleagues discovered a pain control pathway that links the cingulate cortex in the front of the brain, through the pons region of the brainstem, to cerebellum in the back of the brain.
In a study in ACS Central Science, researchers have identified a strategy to design safer opioids. They showed that an experimental opioid, which binds to an unconventional spot in the receptor, suppresses pain in animal models with fewer side effects — most notably those linked to fatal overdoses.
A multi-institutional study found that 1 in 6 youths fill an opioid prescription prior to surgery, and 3% of patients were still filling opioid prescriptions three to six months after surgery, indicating persistent opioid use and possible opioid dependence.
Physical therapy can be a life changer, helping people address chronic pain, recovery from surgery or injury, or getting back to a beloved sport. But that’s only if physical therapy is done — and done right. Faculty from the Tufts University School of Medicine Department of Rehabilitation Sciences offer tips on doing physical therapy at home.
Inequities in pain medication treatment received postpartum, after giving birth, were found in a Cedars-Sinai study of 18,000 women. The disparities were observed even among patients reporting the highest pain levels.
The American Neuromuscular Foundation is excited to announce Isván Alvarez Herrera, CNCT, as the recipient of the 2024 Technologist Best Abstract Award for his abstract titled, “Cutaneous Silent Period in a Patient With Warm Complex Regional Pain Syndrome.”
A new study led by researchers with The Ohio State University Wexner Medical Center and College of Medicine found that the most profound source of distress for patients with sickle cell disease in a home visit program was anticipating and going to acute care centers to manage their acute pain.
A drug used to prevent migraine may also be effective in people with migraine who experience rebound headaches, according to a new study published in the June 26, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Research published in Science Advances traced the history of human’s ability to feel cold back to the molecular underpinnings of the cold and menthol sensor TRPM8 over hundreds of millions of years. The findings could lead to non-addictive pain medications, a crucial development given the opioid crisis.
A new study led by UCLA Health and the U.S. Veterans Affairs Office found chronic pain among older adults could be significantly reduced through a newly developed psychotherapy that works by confronting past trauma and stress-related emotions that can exacerbate pain symptoms.
Knee osteoarthritis (OA) is a common cause of pain and joint stiffness. And while physical activity is known to ease symptoms, only one in 10 people regularly exercise.
Strong family relationships have long been associated with a better sense of well-being and connection. Now a team led by UT Southwestern Medical Center researchers has linked the quality of those relationships with how successfully people – particularly aging African Americans – manage pain.
Everybody has them. A Penn State Health expert with nearly 50 years of experience talks about the best way to treat headaches.
For patients with chronic migraine, nerve decompression surgery effectively reduces the number of headache days – the outcome measure preferred by neurologists – along with other measures including the frequency and intensity of migraine attacks, reports a study in the June issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
A particular form of mindfulness emphasizing pleasure works as well as a starting dose of a narcotic for pain and better than traditional psychotherapy for substance abuse.
MIRA Pharmaceuticals, Inc. (NASDAQ: MIRA) ("MIRA" or the "Company"), a pre-clinical-stage pharmaceutical company focused on the treatment of neurologic and neuropsychiatric disorders, announced it is in advanced discussions with Memorial Sloan Kettering Cancer Center (MSK) to initiate a preclinical study evaluating MIRA's novel oral ketamine analog, Ketamir-2, for the treatment of cancer-related pain and depression.
MIRA Pharmaceuticals, Inc. (NASDAQ: MIRA) ("MIRA" or the "Company"), a pre-clinical-stage pharmaceutical company focused on the treatment of neurologic and neuropsychiatric disorders, announced that it has advanced new preclinical studies using Ketamir-2, its differentiated oral ketamine analog, towards clinical development for the treatment of severe post-traumatic stress disorder (PTSD) and other leading mental health disorders and neuropathic pain indications.
Disc-related back pain may one day meet its therapeutic match: gene therapy delivered by naturally derived nanocarriers that, a new study shows, repairs damaged discs in the spine and lowers pain symptoms in mice.
A new study from the University of South Australia shows how young children learn about the concept of pain through reading, and it’s helping to promote children’s empathy, emotional development, and understand socio-cultural norms.
Complex Regional Pain Syndrome (CRPS) is a chronic and debilitating pain disorder, typically considered lifelong with limited treatment options. Now, groundbreaking research finds that early detection and effective treatment can lead to significant recovery within 18 months, offering hope to millions of people worldwide.
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