doi: 10.1016/0140-6736(93)91409-f.
Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori
Affiliations
- PMID: 8102719
- DOI: 10.1016/0140-6736(93)91409-f
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Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori
Lancet.
.
Abstract
Certain features of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue (MALT) suggest the tumour is antigen-responsive. Given the close association between gastric MALT lymphoma and Helicobacter pylori, these organisms might be evoking the immunological response, and eradication of H pylori might inhibit the tumour. 6 patients in whom biopsies showed histological and molecular-genetic evidence of low-grade gastric B-cell MALT lymphoma with H pylori infection were treated with antibiotics. In all cases H pylori was eradicated and in 5, repeated biopsies showed no evidence of lymphoma. These results suggest that eradication of H pylori causes regression of low-grade B-cell gastric MALT lymphoma, and that anti-H-pylori treatment should be given for this lymphoma.
Comment in
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Gastric lymphomas.Lancet. 1993 Nov 6;342(8880):1182; author reply 1183. doi: 10.1016/0140-6736(93)92168-s. Lancet. 1993. PMID: 7901514 No abstract available.
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Gastric lymphomas.Lancet. 1993 Nov 6;342(8880):1183. Lancet. 1993. PMID: 7901515 No abstract available.
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Gastric lymphomas.Lancet. 1993 Nov 6;342(8880):1183-4. Lancet. 1993. PMID: 7901516 No abstract available.
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Relapse of MALT lymphoma associated with Helicobacter pylori after antibiotic treatment.Lancet. 1994 Apr 30;343(8905):1098-9. doi: 10.1016/s0140-6736(94)90208-9. Lancet. 1994. PMID: 7909113 No abstract available.
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Healing gastric MALT lymphomas by eradicating H pylori?Lancet. 1993 Sep 4;342(8871):568. doi: 10.1016/0140-6736(93)91404-a. Lancet. 1993. PMID: 8102714 No abstract available.
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