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Review
. 2024 Sep:513:3-11.
doi: 10.1016/j.ydbio.2024.05.010. Epub 2024 May 15.

The development of hair follicles and nail

Affiliations
Review

The development of hair follicles and nail

Soung-Hoon Lee et al. Dev Biol. 2024 Sep.

Abstract

The hair follicle and nail unit develop and regenerate through epithelial-mesenchymal interactions. Here, we review some of the key signals and molecular interactions that regulate mammalian hair follicle and nail formation during embryonic development and how these interactions are reutilized to promote their regeneration during adult homeostasis and in response to skin wounding. Finally, we highlight the role of some of these signals in mediating human hair follicle and nail conditions.

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