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. 2021 Nov 26;8(11):003025.
doi: 10.12890/2021_003025. eCollection 2021.

SARS-CoV-2-related Multisystem Inflammatory Syndrome in Adults

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SARS-CoV-2-related Multisystem Inflammatory Syndrome in Adults

António Martins et al. Eur J Case Rep Intern Med. .

Abstract

Adults infected with SARS-CoV-2 may develop a multisystem inflammatory syndrome (MIS-A) characterized by elevated inflammatory markers and multisystem organ involvement. We report the case of a patient who presented with fever and vomiting at hospital admission. He tested positive for SARS-CoV-2 infection and blood tests showed elevated inflammatory markers. The patient developed acute cardiac dysfunction and shock in less than 24 hours and the echocardiogram revealed an LVEF of 30%. He was discharged 3 weeks later fully recovered. MIS-A should be considered if a compatible syndrome is observed in patients with evidence of SARS-CoV-2 infection by PCR test or serology.

Learning points: Multisystem inflammatory syndrome should be considered in young adults presenting with shock and elevated inflammatory markers.Multisystem inflammatory syndrome may be highly responsive to parenteral steroids.

Keywords: SARS-CoV-2; adult patients; multisystem inflammatory syndrome.

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Conflict of interest statement

Conflicts of Interests: The authors declare there are no competing interests.

Figures

Figure 1
Figure 1
Cervical CT: Left enlarged cervical lymph nodes (axial view)
Figure 2
Figure 2
Cervical CT: Right enlarged cervical lymph nodes (axial view)
Figure 3
Figure 3
Thoracic CT: No lung or pleural disease was observed (axial view)

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References

    1. Centers for Disease Control and Prevention. Information for healthcare providers about multisystem inflammatory syndrome in children (MIS-C) [accessed 10 Oct 2021]. Available from: https://www.cdc.gov/mis-c/hcp/
    1. Centers for Disease Control and Prevention. Multisystem inflammatory syndrome in adults (MIS-A) [accessed 10 Oct 2021]. Available from: https://www.cdc.gov/mis-c/mis-a.html.
    1. Morris SB, Schwartz NG, Patel P, Abbo L, Beauchamps L, Balan S, et al. Case series of multisystem inflammatory syndrome in adults associated with SARS-CoV-2 infection - United Kingdom and United States, March–August 2020. MMWR Morb Mortal Wkly Rep. 2020;69(40):1450–1456. doi: 10.15585/mmwr.mm6940e1. - DOI - PMC - PubMed
    1. Bastug A, Aslaner H, Bilir YA, Kemirtlek N, Gursoy FM, Bastug S, et al. Multiple system inflammatory syndrome associated with SARS-CoV-2 infection in an adult and an adolescent. Rheumatol Int. 2021;41:993–1008. doi: 10.1007/s00296-021-04843-1. - DOI - PMC - PubMed
    1. Chau VQ, Giustino G, Mahmood K, Oliveros E, Neibart E, Oloomi M, et al. Cardiogenic shock and hyperinflammatory syndrome in young males with COVID-19. Circ Heart Fail. 2020;13(10):e007485. doi: 10.1161/CIRCHEARTFAILURE.120.007485. - DOI - PubMed

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