Diet, Stress and Mental Health
- PMID: 32823562
- PMCID: PMC7468813
- DOI: 10.3390/nu12082428
Diet, Stress and Mental Health
Abstract
Introduction: There has long been an interest in the effects of diet on mental health, and the interaction of the two with stress; however, the nature of these relationships is not well understood. Although associations between diet, obesity and the related metabolic syndrome (MetS), stress, and mental disorders exist, causal pathways have not been established.
Methods: We reviewed the literature on the relationship between diet, stress, obesity and psychiatric disorders related to stress.
Results: Diet and obesity can affect mood through direct effects, or stress-related mental disorders could lead to changes in diet habits that affect weight. Alternatively, common factors such as stress or predisposition could lead to both obesity and stress-related mental disorders, such as depression and posttraumatic stress disorder (PTSD). Specific aspects of diet can lead to acute changes in mood as well as stimulate inflammation, which has led to efforts to assess polyunsaturated fats (PUFA) as a treatment for depression. Bidirectional relationships between these different factors are also likely. Finally, there has been increased attention recently on the relationship between the gut and the brain, with the realization that the gut microbiome has an influence on brain function and probably also mood and behavior, introducing another way diet can influence mental health and disorders. Brain areas and neurotransmitters and neuropeptides that are involved in both mood and appetite likely play a role in mediating this relationship.
Conclusions: Understanding the relationship between diet, stress and mood and behavior could have important implications for the treatment of both stress-related mental disorders and obesity.
Keywords: Mediterranean diet; brain; cardiovascular disease; child abuse; coronary artery disease; depressive disorder; diet; galanin; ghrelin; metabolic syndrome; microbiome; myocardial ischemia; nutrition; obesity; posttraumatic; serotonin; somatostatin; stress disorders.
Conflict of interest statement
None of the authors have a relevant financial conflict to disclose.
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References
-
- Perk J., De Backer G., Gohlke H., Graham I., Reiner Z., Verschuren M., Albus C., Benlian P., Boysen G., Cifkova R., et al. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR) Eur. Heart J. 2012;33:1635–1701. doi: 10.1093/eurheartj/ehs092. - DOI - PubMed
-
- Vaccarino V., Votaw J., Faber T., Veledar E., Murrah N.V., Jones L.R., Zhao J., Su S., Goldberg J., Raggi J.P., et al. Major depression and coronary flow reserve detected by positron emission tomography. Arch. Intern. Med. 2009;169:1668–1676. doi: 10.1001/archinternmed.2009.330. - DOI - PMC - PubMed
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