Review

. 2017;4(1):27-39.

doi: 10.1007/s40475-017-0101-y. Epub 2017 Mar 17.

Surveillance of Arthropod-Borne Viruses and Their Vectors in the Mediterranean and Black Sea Regions Within the MediLabSecure Network

Anna-Bella Failloux^#¹, Ali Bouattour^#², Chafika Faraj^#³, Filiz Gunay^#⁴, Nabil Haddad^#⁵, Zoubir Harrat^#⁶, Elizabeta Jancheska^#⁷, Khalil Kanani^#⁸, Mohamed Amin Kenawy^#⁹, Majlinda Kota^#¹⁰, Igor Pajovic^#¹¹, Lusine Paronyan^#¹², Dusan Petric^#¹³, Mhammed Sarih^#¹⁴, Samir Sawalha^#¹⁵, Taher Shaibi^#¹⁶, Kurtesh Sherifi^#¹⁷, Tatiana Sulesco^#¹⁸, Enkelejda Velo^#¹⁹, Lobna Gaayeb^#²⁰, Kathleen Victoir^#²⁰, Vincent Robert^#²¹

Affiliations

¹ Department of Virology, Arboviruses and Insect Vectors, Institut Pasteur, Paris, France.
² Laboratory of Medical Entomology, Institut Pasteur of Tunis, Tunis, Tunisia.
³ Laboratory of Medical Entomology, Institut National d'Hygiène, Rabat, Morocco.
⁴ Hacettepe University, HU-ESRL-VERG, Ankara, Turkey.
⁵ Faculty of Public Health, Laboratory of Immunology, Lebanese University, Beirut, Lebanon.
⁶ Eco-Epidemiologie Parasitaire et Génétique des Populations, Institut Pasteur of Algeria, Alger, Algeria.
⁷ Laboratory for Virology and Molecular Diagnostics, Institute of Public Health, Skopje, Macedonia.
⁸ Parasitic and Zoonotic Diseases Department, Ministry of Health, Amman, Jordan.
⁹ Department of Entomology, Faculty of Science, Ain Shams University, Cairo, Egypt.
¹⁰ Department of Control of Infectious Diseases, Laboratory of Virology, Institute of Public Health, Tirana, Albania.
¹¹ Biotechnical Faculty, Laboratory for Applied Zoology, University of Montenegro, Podgorica, Montenegro.
¹² Vector Borne and Parasitic Diseases Epidemiology Department, National Center for Diseases Control and Prevention, Yerevan, Armenia.
¹³ Faculty of Agriculture, Laboratory of Medical and Veterinary Entomology, University of Novi Sad, Novi Sad, Serbia.
¹⁴ Laboratory of Vectorial Diseases, Institut Pasteur of Morocco, Casablanca, Morocco.
¹⁵ Laboratory of Public Health, Ministry of Health, Ramallah, Palestine.
¹⁶ Laboratory of Parasitology and Vector-Borne Diseases, National Center for Disease Control, Tripoli, Libya.
¹⁷ Faculty of Agriculture and Veterinary Science, Institute of Veterinary Medicine, University of Prishtina, Prishtina, Kosovo.
¹⁸ Laboratory of Systematics and Molecular Phylogeny, Institute of zoology, Chisinau, Republic of Moldova.
¹⁹ Department of Control of Infectious Diseases, Vector Control Unit, Laboratory of Medical Entomology, Institute of Public Health, Tirana, Albania.
²⁰ Department of International Affairs, Institut Pasteur, Paris, France.
²¹ French National Research Institute for Sustainable Development, MIVEGEC Unit, IRD224-CNRS 5290-Montpellier University, Montpellier, France.

^# Contributed equally.

PMID: 28386524
PMCID: PMC5362652
DOI: 10.1007/s40475-017-0101-y

Review

Surveillance of Arthropod-Borne Viruses and Their Vectors in the Mediterranean and Black Sea Regions Within the MediLabSecure Network

Anna-Bella Failloux et al. Curr Trop Med Rep. 2017.

. 2017;4(1):27-39.

doi: 10.1007/s40475-017-0101-y. Epub 2017 Mar 17.

Authors

Affiliations

¹ Department of Virology, Arboviruses and Insect Vectors, Institut Pasteur, Paris, France.
² Laboratory of Medical Entomology, Institut Pasteur of Tunis, Tunis, Tunisia.
³ Laboratory of Medical Entomology, Institut National d'Hygiène, Rabat, Morocco.
⁴ Hacettepe University, HU-ESRL-VERG, Ankara, Turkey.
⁵ Faculty of Public Health, Laboratory of Immunology, Lebanese University, Beirut, Lebanon.
⁶ Eco-Epidemiologie Parasitaire et Génétique des Populations, Institut Pasteur of Algeria, Alger, Algeria.
⁷ Laboratory for Virology and Molecular Diagnostics, Institute of Public Health, Skopje, Macedonia.
⁸ Parasitic and Zoonotic Diseases Department, Ministry of Health, Amman, Jordan.
⁹ Department of Entomology, Faculty of Science, Ain Shams University, Cairo, Egypt.
¹⁰ Department of Control of Infectious Diseases, Laboratory of Virology, Institute of Public Health, Tirana, Albania.
¹¹ Biotechnical Faculty, Laboratory for Applied Zoology, University of Montenegro, Podgorica, Montenegro.
¹² Vector Borne and Parasitic Diseases Epidemiology Department, National Center for Diseases Control and Prevention, Yerevan, Armenia.
¹³ Faculty of Agriculture, Laboratory of Medical and Veterinary Entomology, University of Novi Sad, Novi Sad, Serbia.
¹⁴ Laboratory of Vectorial Diseases, Institut Pasteur of Morocco, Casablanca, Morocco.
¹⁵ Laboratory of Public Health, Ministry of Health, Ramallah, Palestine.
¹⁶ Laboratory of Parasitology and Vector-Borne Diseases, National Center for Disease Control, Tripoli, Libya.
¹⁷ Faculty of Agriculture and Veterinary Science, Institute of Veterinary Medicine, University of Prishtina, Prishtina, Kosovo.
¹⁸ Laboratory of Systematics and Molecular Phylogeny, Institute of zoology, Chisinau, Republic of Moldova.
¹⁹ Department of Control of Infectious Diseases, Vector Control Unit, Laboratory of Medical Entomology, Institute of Public Health, Tirana, Albania.
²⁰ Department of International Affairs, Institut Pasteur, Paris, France.
²¹ French National Research Institute for Sustainable Development, MIVEGEC Unit, IRD224-CNRS 5290-Montpellier University, Montpellier, France.

^# Contributed equally.

PMID: 28386524
PMCID: PMC5362652
DOI: 10.1007/s40475-017-0101-y

Abstract

Purpose of review: Arboviruses, viruses transmitted by arthropods such as mosquitoes, ticks, sandflies, and fleas are a significant threat to public health because of their epidemic and zoonotic potential. The geographical distribution of mosquito-borne diseases such as West Nile (WN), Rift Valley fever (RVF), Dengue, Chikungunya, and Zika has expanded over the last decades. Countries of the Mediterranean and Black Sea regions are not spared. Outbreaks of WN are repeatedly reported in the Mediterranean basin. Human cases of RVF were reported at the southern borders of the Maghreb region. For this reason, establishing the basis for the research to understand the potential for the future emergence of these and other arboviruses and their expansion into new geographic areas became a public health priority. In this context, the European network "MediLabSecure" gathering laboratories in 19 non-EU countries from the Mediterranean and Black Sea regions seeks to improve the surveillance (of animals, humans, and vectors) by reinforcing capacity building and harmonizing national surveillance systems to address this important human and veterinary health issue. The aim of this review is to give an exhaustive overview of arboviruses and their vectors in the region.

Recent findings: The data presented underline the importance of surveillance in the implementation of more adapted control strategies to combat vector-borne diseases. Partner laboratories within the MediLabSecure network present a wide range of infrastructures and have benefited from different training programs.

Summary: Although reporting of arboviral presence is not carried out in a systematic manner, the expansion of the area where arboviruses are present cannot be disputed. This reinforces the need for increasing surveillance capacity building in this region to prevent future emergences.

Keywords: Arboviruses; Emergence; Mediterranean and Black Sea regions; Surveillance; Vectors.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest

All authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Figures

**Fig. 1**
Map showing the arboviruses detected in countries that are partners of the MediLabsecure network

See this image and copyright information in PMC

Cited by

Seroprevalence and Risk Factors Associated with Phleboviruses and Crimean-Congo Hemorrhagic Fever Virus among Blood Donors in Central Tunisia.
Ayari R, Chaouch H, Findlay-Wilson S, Hachfi W, Ben Lasfar N, Bellazreg F, Dowall S, Hannachi N, Letaief A. Ayari R, et al. Pathogens. 2024 Apr 22;13(4):348. doi: 10.3390/pathogens13040348. Pathogens. 2024. PMID: 38668303 Free PMC article.
Detection and phylogenetic analysis of kinetoplast DNA of Leishmania infantum infected humans, domestic dogs and sandflies in Northwest Iran.
Behniafar H, Taghipour N, Spotin A, Zare Z, Tabaei SJS, Kazemirad E, Moin Vaziri V, Mohebali M. Behniafar H, et al. PLoS One. 2024 Mar 13;19(3):e0296777. doi: 10.1371/journal.pone.0296777. eCollection 2024. PLoS One. 2024. PMID: 38478521 Free PMC article.
Ixodid ticks and zoonotic tick-borne pathogens of the Western Balkans.
Kapo N, Zuber Bogdanović I, Gagović E, Žekić M, Veinović G, Sukara R, Mihaljica D, Adžić B, Kadriaj P, Cvetkovikj A, Djadjovski I, Potkonjak A, Velo E, Savić S, Tomanović S, Omeragić J, Beck R, Hodžić A. Kapo N, et al. Parasit Vectors. 2024 Jan 31;17(1):45. doi: 10.1186/s13071-023-06116-1. Parasit Vectors. 2024. PMID: 38297327 Free PMC article. Review.
Nondestructive Methods of Pathogen Detection: Importance of Mosquito Integrity in Studies of Disease Transmission and Control.
Meireles ACA, Rios FGF, Feitoza LHM, da Silva LR, Julião GR. Meireles ACA, et al. Pathogens. 2023 Jun 8;12(6):816. doi: 10.3390/pathogens12060816. Pathogens. 2023. PMID: 37375506 Free PMC article. Review.
West Nile, Sindbis and Usutu Viruses: Evidence of Circulation in Mosquitoes and Horses in Tunisia.
M'ghirbi Y, Mousson L, Moutailler S, Lecollinet S, Amaral R, Beck C, Aounallah H, Amara M, Chabchoub A, Rhim A, Failloux AB, Bouattour A. M'ghirbi Y, et al. Pathogens. 2023 Feb 21;12(3):360. doi: 10.3390/pathogens12030360. Pathogens. 2023. PMID: 36986282 Free PMC article.

See all "Cited by" articles

References

1. Amraoui F, Failloux AB. Chikungunya: an unexpected emergence in Europe. Curr Opin Virol. 2016;21:146–50. - PubMed
1. Rezza G. Dengue and chikungunya: long-distance spread and outbreaks in naive areas. Pathog Glob Health. 2014;108(8):349–55. - PMC - PubMed
1. Septfons A, Leparc-Goffart I, Couturier E, Franke F, Deniau J, Balestier A, et al. Travel-associated and autochthonous Zika virus infection in mainland France, 1 January to 15 July 2016. Eur Surveill. 2016;21(32):30315. - PMC - PubMed
1. •• Escadafal C, Gaayeb L, Riccardo F, Perez-Ramirez E, Picard M, Dente MG, et al. Risk of Zika virus transmission in the Euro-Mediterranean area and the added value of building preparedness to arboviral threats from a one health perspective. BMC Public Health. 2016;16(1):1219. The MediLabSecure network, created in 2014, comprising 55 laboratories in 19 countries in the Mediterranean and the Black Sea regions, aims to improve capacity-building for arbovirus diagnostics through trainings on techniques common to several arboviruses, including Zika.. - PMC - PubMed
1. Rosen L. Dengue in Greece in 1927 and 1928 and the pathogenesis of dengue hemorrhagic fever: new data and a different conclusion. Am J Trop Med Hyg. 1986;35(3):642–53. - PubMed

Publication types

Actions

LinkOut - more resources

Full Text Sources
- Europe PubMed Central
- PubMed Central
Other Literature Sources
- scite Smart Citations
Research Materials
- NCI CPTC Antibody Characterization Program

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Surveillance of Arthropod-Borne Viruses and Their Vectors in the Mediterranean and Black Sea Regions Within the MediLabSecure Network

Affiliations

Surveillance of Arthropod-Borne Viruses and Their Vectors in the Mediterranean and Black Sea Regions Within the MediLabSecure Network

Authors

Affiliations

Abstract

Conflict of interest statement

Conflict of Interest

Human and Animal Rights and Informed Consent

Figures

Similar articles

Cited by

References

Publication types

LinkOut - more resources

Full Text Sources

Other Literature Sources

Research Materials

Abstract

Conflict of interest statement

Conflict of Interest

Human and Animal Rights and Informed Consent

Figures

Similar articles

Cited by

References

Publication types

Related information

LinkOut - more resources

Full Text Sources

Other Literature Sources

Research Materials