Association of Depression, Anxiety, and Type D Personality with Cognitive Function in Patients with Coronary Artery Disease
- PMID: 27336806
- DOI: 10.1097/WNN.0000000000000093
Association of Depression, Anxiety, and Type D Personality with Cognitive Function in Patients with Coronary Artery Disease
Abstract
Background and objective: Cognitive impairment predicts poor outcomes in patients with coronary artery disease (CAD), but much remains to be learned about these patients' cognitive function. We investigated how depression, anxiety, and Type D personality relate to cognitive function in patients with CAD, adjusting for sociodemographic factors and clinical markers of CAD severity.
Methods: We evaluated 510 consecutive patients with CAD (364 men, 146 women; mean age 58±9 years) but no history of coronary artery bypass graft surgery or cognitive impairment who were attending a cardiac rehabilitation program. We assessed the patients' cognitive function (Mini-Mental State Examination, Digit Span Test, Digit Symbol Test, and Trail Making Test Part A), depressive symptoms (Beck Depression Inventory-II), anxiety (State-Trait Anxiety Inventory), Type D personality (14-item Type D Scale), and clinical markers of CAD severity.
Results: After adjusting for sex, age, education, New York Heart Association functional class, and left ventricular ejection fraction, we found that higher depression symptom scores correlated with longer Digit Symbol Test completion time (β=0.158, P<0.004). Higher state anxiety scores correlated with worse Digit Span Test backward recall (β=-0.117, P<0.008) and Trail Making Test Part A scores (β=0.182, P<0.004). Type D personality correlated with lower Mini-Mental State Examination scores (β=-0.148, P=0.001).
Conclusions: For patients with CAD undergoing a cardiac rehabilitation program, depression, anxiety, and Type D personality were associated with worse cognitive performance independent of clinical CAD severity and sociodemographic characteristics.
Similar articles
-
The relationship between coronary artery disease and depression and anxiety scores.North Clin Istanb. 2020 Aug 5;7(5):523-526. doi: 10.14744/nci.2020.72602. eCollection 2020. North Clin Istanb. 2020. PMID: 33163893 Free PMC article. Review.
-
Mental Distress Factors and Exercise Capacity in Patients with Coronary Artery Disease Attending Cardiac Rehabilitation Program.Int J Behav Med. 2018 Feb;25(1):38-48. doi: 10.1007/s12529-017-9675-y. Int J Behav Med. 2018. PMID: 28702757
-
The Association of Type D personality with Heart Rate Variability and Lipid Profiles Among Patients with Coronary Artery Disease.Int J Behav Med. 2017 Feb;24(1):101-109. doi: 10.1007/s12529-016-9571-x. Int J Behav Med. 2017. PMID: 27229521
-
Decreased physical effort, fatigue, and mental distress in patients with coronary artery disease: importance of personality-related differences.Int J Behav Med. 2014 Apr;21(2):240-7. doi: 10.1007/s12529-013-9299-9. Int J Behav Med. 2014. PMID: 23456184
-
Symptom perception in CHF: (why mind matters).Heart Fail Rev. 2009 Mar;14(1):29-34. doi: 10.1007/s10741-007-9059-5. Epub 2007 Dec 11. Heart Fail Rev. 2009. PMID: 18071897 Review.
Cited by
-
The Influence of Personality Type D and Coping Strategies on Cognitive Functioning in Students.Behav Sci (Basel). 2024 May 1;14(5):382. doi: 10.3390/bs14050382. Behav Sci (Basel). 2024. PMID: 38785873 Free PMC article.
-
A randomised controlled trial assessing the effects of weather sensitivity profile and walking in nature on the psychophysiological response to stress in individuals with coronary artery disease. A study protocol.BMC Psychol. 2024 Feb 19;12(1):82. doi: 10.1186/s40359-024-01574-3. BMC Psychol. 2024. PMID: 38374158 Free PMC article.
-
Acute Myocardial Infarction and Risk of Cognitive Impairment and Dementia: A Review.Biology (Basel). 2023 Aug 21;12(8):1154. doi: 10.3390/biology12081154. Biology (Basel). 2023. PMID: 37627038 Free PMC article. Review.
-
Neural Dysconnectivity in the Hippocampus Correlates With White Matter Lesions and Cognitive Measures in Patients With Coronary Artery Disease.Front Aging Neurosci. 2022 Jun 27;14:786253. doi: 10.3389/fnagi.2022.786253. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35832064 Free PMC article.
-
Irregular Baseline Brain Activity in Coronary Artery Disease Patients with Cognitive Impairment: A Resting-state Functional Magnetic Resonance Imaging Study.Curr Neurovasc Res. 2022;19(2):131-136. doi: 10.2174/1567202619666220516124552. Curr Neurovasc Res. 2022. PMID: 35578846 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous