Inferring mental states from neuroimaging data: from reverse inference to large-scale decoding
- PMID: 22153367
- PMCID: PMC3240863
- DOI: 10.1016/j.neuron.2011.11.001
Inferring mental states from neuroimaging data: from reverse inference to large-scale decoding
Abstract
A common goal of neuroimaging research is to use imaging data to identify the mental processes that are engaged when a subject performs a mental task. The use of reasoning from activation to mental functions, known as "reverse inference," has been previously criticized on the basis that it does not take into account how selectively the area is activated by the mental process in question. In this Perspective, I outline the critique of informal reverse inference and describe a number of new developments that provide the ability to more formally test the predictive power of neuroimaging data.
Copyright © 2011 Elsevier Inc. All rights reserved.
Figures
Similar articles
-
Reverse inference is not a fallacy per se: cognitive processes can be inferred from functional imaging data.Neuroimage. 2014 Jan 1;84:1061-9. doi: 10.1016/j.neuroimage.2012.12.075. Epub 2013 Jan 11. Neuroimage. 2014. PMID: 23313571 Review.
-
The brain network for deductive reasoning: a quantitative meta-analysis of 28 neuroimaging studies.J Cogn Neurosci. 2011 Nov;23(11):3483-97. doi: 10.1162/jocn_a_00063. Epub 2011 May 13. J Cogn Neurosci. 2011. PMID: 21568632 Free PMC article.
-
Decoding the large-scale structure of brain function by classifying mental States across individuals.Psychol Sci. 2009 Nov;20(11):1364-72. doi: 10.1111/j.1467-9280.2009.02460.x. Epub 2009 Oct 30. Psychol Sci. 2009. PMID: 19883493 Free PMC article.
-
Anatomy of deductive reasoning.Trends Cogn Sci. 2007 Oct;11(10):435-41. doi: 10.1016/j.tics.2007.09.003. Epub 2007 Oct 2. Trends Cogn Sci. 2007. PMID: 17913567 Review.
-
If neuroimaging is the answer, what is the question?Philos Trans R Soc Lond B Biol Sci. 1999 Jul 29;354(1387):1283-94. doi: 10.1098/rstb.1999.0479. Philos Trans R Soc Lond B Biol Sci. 1999. PMID: 10466151 Free PMC article. Review.
Cited by
-
False memories in forensic psychology: do cognition and brain activity tell the same story?Front Psychol. 2024 May 16;15:1327196. doi: 10.3389/fpsyg.2024.1327196. eCollection 2024. Front Psychol. 2024. PMID: 38827889 Free PMC article. Review.
-
Refuting Six Misconceptions about Romantic Love.Behav Sci (Basel). 2024 May 2;14(5):383. doi: 10.3390/bs14050383. Behav Sci (Basel). 2024. PMID: 38785874 Free PMC article. Review.
-
The inter-relationships of the neural basis of rumination and inhibitory control: neuroimaging-based meta-analyses.Psychoradiology. 2022 Mar 17;2(1):11-22. doi: 10.1093/psyrad/kkac002. eCollection 2022 Mar. Psychoradiology. 2022. PMID: 38665140 Free PMC article. Review.
-
Stimulus shapes strategy: Effects of stimulus characteristics and individual differences in academic achievement on the neural mechanisms engaged during the N-back task.Dev Cogn Neurosci. 2024 Apr;66:101372. doi: 10.1016/j.dcn.2024.101372. Epub 2024 Mar 27. Dev Cogn Neurosci. 2024. PMID: 38593494 Free PMC article.
-
Limited but specific engagement of the mature language network during linguistic statistical learning.Cereb Cortex. 2024 Apr 1;34(4):bhae123. doi: 10.1093/cercor/bhae123. Cereb Cortex. 2024. PMID: 38566510
References
-
- Aguirre GK. Functional imaging in behavioral neurology and cognitive neuropsychology. In: Feinberg TE, Farah MJ, editors. Behavioral Neurology and Cognitive Neuropsychology. McGraw-Hill; 2003.
-
- Carroll MK, Cecchi GA, Rish I, Garg R, Rao AR. Prediction and interpretation of distributed neural activity with sparse models. Neuroimage. 2009;44(1):112–22. - PubMed
-
- Davatzikos C, Ruparel K, Fan Y, Shen DG, Acharyya M, Loughead JW, Gur RC, Langleben DD. Classifying spatial patterns of brain activity with machine learning methods: application to lie detection. Neuroimage. 2005;28(3):663–8. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources