Effects of moderate-fat (from monounsaturated fat) and low-fat weight-loss diets on the serum lipid profile in overweight and obese men and women
- PMID: 14749224
- DOI: 10.1093/ajcn/79.2.204
Effects of moderate-fat (from monounsaturated fat) and low-fat weight-loss diets on the serum lipid profile in overweight and obese men and women
Abstract
Background: Little evidence of the effects of moderate-fat (from monounsaturated fat) weight-loss diets on risk factors for cardiovascular disease exists because low-fat diets are typically recommended. Previous studies in weight-stable persons showed that a moderate-fat diet results in a more favorable lipid and lipoprotein profile (ie, lower serum triacylglycerol and higher HDL cholesterol) than does a low-fat diet.
Objective: We evaluated the effects of energy-controlled, low-fat and moderate-fat diets on changes in lipids and lipoproteins during weight loss and subsequent weight maintenance.
Design: We conducted a parallel-arm study design in overweight and obese [body mass index (in kg/m(2)): 29.8 +/- 2.4] healthy men and women (n = 53) assigned to consume a low-fat (18% of energy) or moderate-fat (33% of energy) diet for 6 wk to achieve weight loss, which was followed by 4 wk of weight maintenance. All foods were provided and body weight was monitored to ensure equal weight loss between groups.
Results: The moderate-fat diet elicited favorable changes in the lipoprotein profile. Compared with baseline, HDL cholesterol was unchanged, whereas triacylglycerol and the ratios of total and non-HDL cholesterol to HDL cholesterol were lower at the end of the weight-maintenance period in the moderate-fat diet group. Despite similar weight loss, triacylglycerol rebounded, HDL cholesterol decreased, and the ratios of total and non-HDL cholesterol to HDL cholesterol did not change during the 10-wk interval in the low-fat diet group.
Conclusions: A moderate-fat weight-loss and weight-maintenance diet improves the cardiovascular disease risk profile on the basis of favorable changes in lipids and lipoproteins. There is merit in recommending a moderate-fat weight-loss diet.
Similar articles
-
Dynamics of intrapericardial and extrapericardial fat tissues during long-term, dietary-induced, moderate weight loss.Am J Clin Nutr. 2017 Oct;106(4):984-995. doi: 10.3945/ajcn.117.157115. Epub 2017 Aug 16. Am J Clin Nutr. 2017. PMID: 28814394
-
Comparison of effects of long-term low-fat vs high-fat diets on blood lipid levels in overweight or obese patients: a systematic review and meta-analysis.J Acad Nutr Diet. 2013 Dec;113(12):1640-61. doi: 10.1016/j.jand.2013.07.010. Epub 2013 Oct 17. J Acad Nutr Diet. 2013. PMID: 24139973 Review.
-
Effect of an energy-restricted, high-protein, low-fat diet relative to a conventional high-carbohydrate, low-fat diet on weight loss, body composition, nutritional status, and markers of cardiovascular health in obese women.Am J Clin Nutr. 2005 Jun;81(6):1298-306. doi: 10.1093/ajcn/81.6.1298. Am J Clin Nutr. 2005. PMID: 15941879 Clinical Trial.
-
Substitution of high monounsaturated fatty acid avocado for mixed dietary fats during an energy-restricted diet: effects on weight loss, serum lipids, fibrinogen, and vascular function.Nutrition. 2005 Jan;21(1):67-75. doi: 10.1016/j.nut.2004.09.010. Nutrition. 2005. PMID: 15661480 Clinical Trial.
-
Effects of a low-fat diet compared with those of a high-monounsaturated fat diet on body weight, plasma lipids and lipoproteins, and glycemic control in type 2 diabetes.Am J Clin Nutr. 2004 Sep;80(3):668-73. doi: 10.1093/ajcn/80.3.668. Am J Clin Nutr. 2004. PMID: 15321807 Clinical Trial.
Cited by
-
Tree Nut and Peanut Consumption and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Adv Nutr. 2023 Sep;14(5):1029-1049. doi: 10.1016/j.advnut.2023.05.004. Epub 2023 May 5. Adv Nutr. 2023. PMID: 37149262 Free PMC article. Review.
-
Association between the rs3812316 Single Nucleotide Variant of the MLXIPL Gene and Alpha-Linolenic Acid Intake with Triglycerides in Mexican Mestizo Women.Nutrients. 2022 Nov 9;14(22):4726. doi: 10.3390/nu14224726. Nutrients. 2022. PMID: 36432414 Free PMC article.
-
Effect of Consuming Beef with Varying Fatty Acid Compositions as a Major Source of Protein in Volunteers under a Personalized Nutritional Program.Nutrients. 2022 Sep 9;14(18):3711. doi: 10.3390/nu14183711. Nutrients. 2022. PMID: 36145087 Free PMC article. Clinical Trial.
-
Association of nut consumption with CVD risk factors in young to middle-aged adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study.Nutr Metab Cardiovasc Dis. 2022 Oct;32(10):2321-2329. doi: 10.1016/j.numecd.2022.07.013. Epub 2022 Jul 31. Nutr Metab Cardiovasc Dis. 2022. PMID: 35970686 Free PMC article.
-
Effect of Crushing Peanuts on Fatty Acid and Phenolic Bioaccessibility: A Long-Term Study.Antioxidants (Basel). 2022 Feb 19;11(2):423. doi: 10.3390/antiox11020423. Antioxidants (Basel). 2022. PMID: 35204306 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical