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Case Reports
. 2010 Apr 1;1(2):e80-e83.
doi: 10.1016/j.jccase.2009.08.001.

Giant coronary artery aneurysms in a Japanese octogenarian - The oldest case of Kawasaki Disease?

Affiliations
Case Reports

Giant coronary artery aneurysms in a Japanese octogenarian - The oldest case of Kawasaki Disease?

Stephen G Chun et al. J Cardiol Cases. .

Abstract

Kawasaki disease (KD) is a leading cause of non-atherosclerotic coronary artery aneurysms and, less commonly, peripheral artery aneurysms. We report an 81-year-old Japanese man from Hawaii with a history of an abdominal aortic aneurysm, bilateral iliac aneurysms, and an ambiguous right atrial cystic mass. The patient developed new-onset atrial fibrillation during lithotripsy. Angiography and magnetic resonance imaging revealed giant coronary artery aneurysms of the right coronary artery (RCA) and left anterior descending artery, and a thoracic aortic aneurysm. The RCA aneurysm was greater than 2 inches in diameter at the time of operation. Although we cannot confirm whether the patient had KD during childhood, this is the most likely diagnosis in the absence of a connective tissue disorder, systemic vasculitis, or atherosclerotic risk factors. This patient may represent the oldest case of KD, predating the earliest known case by more than 20 years. This case sheds light on the historical epidemiology of KD and its clinical course, especially regarding late vascular sequelae.

Keywords: Coronary artery aneurysm; Hawaii; Japanese octogenerarian; Kawasaki disease; Mucocutaneous lymph node syndrome; Peripheral artery aneurysm.

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Figures

Figure 1
Figure 1
Echocardiography apical four-chamber view showing a spherical mass (3.6 cm × 3.5 cm) adjacent to the right atrium.
Figure 2
Figure 2
(A) Aneurysm of the left anterior descending artery. (B) Giant aneurysm of the right coronary artery. (C) Aneurysm of the thoracic aorta.
Figure 3
Figure 3
Magnetic resonance imaging of the aneurysms (green arrows). (A) Coronal image of the right coronary artery aneurysm. (B) Axial image of the right coronary artery aneurysm. (C) Axial image of the left anterior descending artery aneurysm.
Figure 4
Figure 4
Intra-operative view of the right coronary artery (RCA) aneurysm. (A) The RCA aneurysm was approximately 5 mm in diameter. (B) Surgical excision revealed extensive atherosclerosis and multiple thrombi adherent to the wall of the aneurysm.

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