Extended Data Fig. 5: Central and effector memory CD8+ T cell responses to SARS-CoV-2 variants.
From: Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans
Spike-specific pooled peptide IFNγ central memory CD27+CD45RA− and effector memory CD27−CD45RA− CD8+ T cell responses by ICS assays against WA1/2020, B.1.351, B.1.1.7, P.1 and CAL.20C on days 57 and 85. Red bars reflect median responses. Dotted lines reflect lower limits of quantification. Filled circles, high dose–placebo; open circles, high dose–high dose; filled triangles, low dose–placebo; open triangles, low dose–low dose. n = 20 independent samples from Ad26.COV2.S vaccine recipients.