Extended Data Fig. 7: Polyfunctional CD8+ and CD4+ T cell responses.
From: Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans
WA1/2020 spike-specific pooled peptide monofunctional and multifunctional IFNγ, IL-2 and TNF CD8+ and CD4+ T cell responses by ICS assays on days 57 and 85. Red bars reflect median responses. Dotted lines reflect lower limits of quantification. Filled circles, high dose–placebo; open circles, high dose–high dose; filled triangles, low dose–placebo; open triangles, low dose–low dose. n = 20 independent samples from Ad26.COV2.S vaccine recipients.