Extended Data Fig. 4: CLL-IPAs generate truncated mRNAs and proteins.
From: Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia
Gene models and western blots of 10 candidates depicted as in Figs. 1b and 2a show that CLL B cells generate full-length and IPA-generated truncated proteins. BLCL were used as control B cells and were included in the 3′-seq tracks. Actin was used as loading control on the same blots. For gel source data see Supplementary Fig. 1.