Manchester United head into this weekend's Premier League action knowing a victory is vital to lift the mood around Old Trafford.

The Reds are at a low spot currently following their chaotic 4-3 defeat to FC Copenhagen in midweek. Defeat in Denmark has put United on the verge of missing out on qualification to the knockout stages.

Erik ten Hag's men sit bottom of their Champions League group and the Premier League does not look much better either. United are eighth in the top flight but a win against Luton will at least brighten the outlook prior to the international break.

READ MORE: United without five players to face Luton

READ MORE: Everything Ten Hag said pre-Luton

However, to do this they will have to contend with a few notable absentees in their squad. MEN Sport has rounded up the injury concerns at Old Trafford.

Jonny Evans

Injury: Unknown

What Ten Hag has said: "We don't have in this moment a full assessment done. We don't have the full details so far. For tomorrow, he's out."

Potential return date: Unknown

Tyrell Malacia

Injury: Knee

What we know: Currently a timeframe for Malacia's return date is still unclear but he has managed to return to individual training after undergoing surgery.

Potential return date: Unknown

Luke Shaw

Injury: Muscular

What we know: Ten Hag has previously stated after the international break is a likely return stage for Shaw but this weekend's clash is too soon.

Potential return date: November 26 vs Everton

Casemiro

Injury: Hamstring

What we know: The Brazilian midfielder was taken off during the defeat to Newcastle in the Carabao Cup and his spell on the sidelines is set to be long-term.

Potential return date: January

Lisandro Martinez

Injury: Foot

What we know: After initially suffering the complaint last season, Martinez has had to undergo surgery to repair the injury. He is now on the road to recovery.

Potential return date: January

Amad

Injury: Knee

What we know: The Ivorian is continuing his battle back to full fitness and posted further videos of himself training last week at Carrington leading some to speculate a return is close.

Potential return date: November/December