Xeltis’ Post

A clinical symphony of Sponsors, CROs, Sites, and Participants for medical advancements #clinicalresearch #clinicaltrials #clinicalresearchassociate #clinicaldevelopment #medicaladvancements #cro #researchanddevelopment #stakeholders #research #goodclinicalpractice #aiinhealthcare

Despite the clinical benefits of oral anticancer medications in B-cell malignancies, managing and monitoring drug adherence remains a clinical challenge. #leusm #lymsm Learn about factors that influence adherence and how you can help your patients overcome these barriers: https://e.lilly/3OgeY3d

Daily Critical Care Pearls #117: 📌Every time your patient is on one of the Neuromuscular Blocking Agents, remember to assess the depth and duration of neuromuscular blockade as below 👇👇👇 📌This practice will guide maintenance of neuromuscular blockade in order indicate when it is safe to extubate the patient 📌Remember: The goal is to avoid clinically significant residual neuromuscular blockade. #ivpn #criticalcare #pharmacy #medicine #clinicalpharmacy #pearls

Concept Medical Receives US FDA IDE Approval For Magictouch AVF Indication, Their Fifth US Clinical Study Approval For The Magictouch Portfolio. Concept Medical has been granted “IDE Approval” from the U.S. Food and Drug Administration (FDA) for MagicTouch AVF, its Sirolimus drug-coated balloon (DCB) catheter, to initiate a clinical study for the treatment of stenotic lesions of Arteriovenous Fistula in the Haemodialysis management of Chronic Renal Failure. This US FDA IDE approval allows Concept Medical to conduct pivotal clinical studies to gather safety and efficacy data for the MagicTouch Sirolimus Coated Balloon in A.V. fistula & support a future pre-market approval (PMA) application in the USA. The complete article at the following link: https://lnkd.in/dU5pS-Qx

Daily Critical Care Pearls #97: Building Fixed-Dose 4-FPCC Warfarin Life-threatening Bleeding Reversal Protocol 💉 The high-risk nature of this clinical scenario necessitates urgency which a protocol facilitates (no need to look up or debate dosing for each patient) 💉 4-FPCC is an expensive medication and waste can be expected to be reduced with a protocol 💉 The ideal dosing regimen for 4-FPCC is a fixed dose and while this has been developed extensively in the medical literature, the prescribing information still recommends a weight-based dose. Therefore an institutional protocol provides both guidance and medical-legal protection for clinicians 💉 Fixed dosing of 4-FPCC compared to variable or weight-based dosing has been proved to reduce: risk of mortality, thromboembolic events, total drug cost, time to drug administration and No need to wait for pretreatment INR results to decide on a dose #criticalcare #pharmacy #medicine #clinicalpharmacy #pearls

FDA Acceptance of The Data from Traditional Chinese Medicine for Heart Health A recent publication of a placebo-controlled clinical trial in China with a Traditional Chinese Medicine (TCM) product showed signification benefits in the management of Acute ST-segment elevation myocardial infarction (STEMI). However, what would be the likelihood of FDA acceptance of clinical data from such a study to support its approval as a conventional drug? Read More: https://lnkd.in/ddqNbsCW #fda #clinicaltrial #clinicalstudies #clinicalreserch #chinesemedicine #gcp #hearthealth #fdaregulation #fdacompliance

Get your investigational medications to patients faster with Caligor Coghlan. #calcog #clinicaltrialsupplies #clinicaltrials #clinicalsupplyservices #comparator #clinicaltrialsupply #expandedaccess #ancillary #labkits

We're proud to share the patient, carer and public 2024 summary report published alongside NICOR's Annual Report and 8 interactive sub-speciality clinical reports. Sarah Murray, Chair of NICOR's Community Representative Group (CAG), said: "The report covers data from 2022/23 and whilst there is good news following the COVID-19 pandemic that some services are back up to capacity, many are not. It is not clear whether there is a lower requirement for some services but there are worrying trends in the lack of consistent provision of services, including operating capacity, variable pharmaceutical pre- and post-operative treatments on offer across the country and life-threatening delays are evident. The devil is in the detail...." The primary aim of the National Cardiac Audit Programme (NCAP) is to support and drive quality improvement within hospitals. Read the report in full: https://bit.ly/49siIHm

Daily Critical Care Pearls #178: Creatinine clearance calculation in amputees You can this calculator as it makes taking amputations into account easy: https://lnkd.in/dSyRXNG8 However, you have to still consider this an estimate of renal function rather than an exact calculation and take into account patient and drug-specific risk:benefit assessments before deciding whether to renally adjust medications for such a patient. #criticalcare #pharmacy #medicine #clinicalpharmacy #pearls

I would like to provide a brief overview of the pharmacotherapy options available for treating heart failure and the latest breakthroughs in this field. #evidencebasedmedicine #HeartHealth #Pharmacotherapy #MedicalAdvancements #medicalaffairs