WVU Heart and Vascular Institute’s Post

Jeremy Kong, MD, and team: Alexander Hardwick, MD, Sheng-Fang Jiang, MS, Ke Sun, MD, David R. Vinson, MD, Dana P. McGlothlin, MD, and Choon Hwa Goh, MD, collaborated with the San Francisco Cardiovascular Disease Fellowship Program and the Kaiser Permanente Northern California Residency and Fellowship Programs to answer this important public health question.  Article: https://lnkd.in/gSwVk9YH   Citation: Kong J, Hardwick A, Jiang SF, Sun K, Vinson DR, McGlothlin DP, Goh CH. CTEPH: A Kaiser Permanente Northern California Experience. Thromb Res. 2023 Jan;221:130-136. doi: 10.1016/j.thromres.2022.09.022. Epub 2022 Dec 22. PMID: 36566069.

Today’s joint session with CVCT - Cardiovascular Clinical Trialists saw excellent discussions about how we can drive lasting change in women’s involvement in clinical trials. - We need more pragmatic eligibility criteria to increase diversity in trial enrolment. - We need to generate data that can apply to patients for whom CV disease is most prevalent and severe. - In order to increase diversity of trial participants, equity must be considered at ALL levels of the trial process, from design to funding to execution. #CVCT2023 Angela Maas, Minnow Walsh, Professor Vijay Kunadian, Terri Cornelison, Jaime Raben, Cynthia (Cindy) Westerhout, Lisa Salberg, Birgit Vogel

According to research just published out of #johnshopkins, it’s estimated that 795,000 Americans die or are permanently disabled each year due to diagnostics errors. Among health conditions, vascular events, infections, and cancer accounted for 75% of the occurrences. A disease-focused approach to diagnostic error prevention and mitigation has the potential to significantly reduce these harms. #deerbornedifference #diagnostics #venturecapital #privateequity

Ophthopedia Update:Reply: We thank Drs Elhusseiny, Grigorian, and Sallam for their interest in our study and for the opportunity to address the main topics of their commentary. First, we thank the authors for bringing the publication by Conner et al1 to our attention. The reference was omitted from our work due to timing. Our work was in preparation while that work was being published. The work by Conner et al1 adds to the growing literature demonstrating the efficacy of the use of oral fluorescein ingestion to delineate retinal disease processes in the pediatric population. #Ophthalmology #Retina #Ophthotwitter

Evidence suggests that arterial stiffness, a measure of vascular dysfunction, is greater in persons with MS. However, physical activity may help mitigate arterial stiffening and thus mitigate effects on walking and cognitive performance. This recent article by Noah DuBose, Sydney R. DeJonge, MS, Dr. Brenda Jeng, and Dr. Rob Motl reviews the existing research on vascular dysfunction in multiple sclerosis. They found that there is a lack of evidence regarding vascular dysfunction in MS in comparison to research on vascular comorbidity in MS and the role of vascular dysfunction in other chronic conditions and diseases. Our lab is already working hard to fill these gaps in the knowledge surrounding the mechanisms contributing to MS outcomes, but we are excited as this article highlights important next steps as we continue our work! Read the full article here: https://lnkd.in/g6Z-8VqW. 

The ability for innovation precincts to identify their R&D strengths and then double down on those in investment, education, collaborative partnerships and more is vital to their ultimate success. That’s why the announcement yesterday that Liverpool Innovation Precinct (LIP) member, the Ingham Institute for Applied Medical Research was partnering with the world leading Victor Chang Cardiac Research Institute, will go down as a landmark event in the LIP’s history. Launched by NSW Minister for Medical Research Hon. David Harris, the partnership establishes a powerful cardiac research hub in South Western Sydney, a region which experiences the highest incidence of cardiovascular-related hospital admissions in NSW. Ingham Institute Director, Prof. Les Bokey said: “This is the start of a partnership that will lead to major improvements in cardiovascular health, which will have local and national influence. Partnerships such as these are essential in turning the tide of Australia’s biggest killer.” Prof. Jason Kovacic, Institute Director and CEO Victor Chang Cardiac Research Institute, says the partnership brings together two internationally renowned biomedical research institutes. “The benefits of this partnership will go far beyond NSW and will improve patient outcomes for all those suffering from cardiovascular disease,” The strategic partnership is also joined by LIP members, UNSW Sydney and the South Western Sydney Local Health District. A foundation initiative of the partnership is the establishment of a new Chair in Cardiovascular Research based at Liverpool Hospital. This new appointment will significantly boost heart disease research and accelerate future scientific breakthroughs. Anne O'Neill, Ryan Park, Sonia Marshall, Stephen Thompson, Simone Proft, Josephine Chow, Ned Mannoun, Greg Warren, Charishma Kaliyanda, Martin Gallagher, Terry Goldacre, Katie Quinn Gilbert, Anita van der Meer, Nathan Hagarty MP, Tina Ayyad, David Borger, Chris Taylor, Adam Leto, Christopher Brown AM, Dr Michael Freelander MP, Anne Stanley, Dai Le MP

🔍 Driving Change in Women's Cardiovascular Health The Global Cardiovascular Research Funders Forum (GCRFF) is on a mission to advance global cardiovascular health through transformative international research in cardiovascular disease. Currently, they are seeking insights from the international cardiovascular research community to address the most urgent research needs for women's cardiovascular health.   👉 How You Can Contribute: Researchers, your expertise is needed! Share your insights by identifying priority research gaps related to women's cardiovascular health from an international perspective. Your responses will play a crucial role in shaping research priorities for an upcoming GCRFF international research funding opportunity.   More information: https://lnkd.in/eyNTjPTY   #CardiovascularResearch #GCRFF #ResearchOpportunity #WomensHealth #GlobalHealth #ResearchPriorities #ClinicalResearch #BHF

Did you know that it is World Liver Day on the 19th of April?🌍 At Owlstone Medical, we believe that breath analysis has enormous potential to support liver disease research. To outline how the composition of breath is related to the mechanisms and pathologies behind liver disease, we have put together our Breath Analysis and the Liver 101 document🌬️. 💡 This short document summarizes the advantages of using breath, what compounds can be analyzed in breath, and how Owlstone Medical can help your liver disease research. You can download the document for free here👇: https://ow.ly/erW850Rbtc3

🧠⚡🩸 Cerebral Hemorrhage: An Unmet Medical Need. On this Rare Disease Day, February 29th, let's focus on cerebral hemorrhage, an orphan disease that remains an unmet medical need. ⚠ According to a recent publication 📰 in The Lancet in February 2024, a growing incidence is expected over the next 25 years, indicating that the outlook for this condition underscores the urgency for a proper response 🛌🏥. In this context, Op2Lysis is firmly committed to addressing this therapeutic gap🔬. Aware of the lack of treatment to date, our company is tirelessly working to develop an innovative solution aimed at effectively reducing the motor and cognitive deficits associated with this devastating condition. 💪 Let's join forces to support medical innovation and offer new hope to those affected by cerebral hemorrhage. #CerebralHemorrhage #OrphanDisease #UnmetMedicalNeed #RareDiseaseDay Medicen Paris Region LégiaPark Christophe Gaudin Jérôme Parcq - Op2Lysis European Innovation Council and SMEs Executive Agency (EISMEA)

Our full-slide summary of the Kwon et al. study “Comparative Risk of Incident and Recurrent Acute Anterior Uveitis across Different Biological Agents in Patients with Ankylosing Spondylitis” is now live on the #IMIDforum! 🚨 The Immune-Mediated Inflammatory Disease forum is a valuable resource for keeping you up to date with hand-selected axSpA publications. Visit the website to view this content and more! 📈 🔗 https://lnkd.in/eqwxACtX #AS #bDMARD #uveitis