Walter Chan, MD, MPH’s Post

Coronary Atherosclerosis Causes, Consequences, and the Passage of Time A must read editorial by Peter Toth and Allan Sniderman Trapping of apoB particles within the arterial wall is the root cause of atherosclerosis and the level of the apoB lipoproteins within plasma is the primary, but not exclusive, determinant of the number of apoB particles that will be trapped over time. Calcification is a histologic hallmark of advanced atherosclerotic disease. Thus, apoB causes atherosclerosis and CAC is a consequence of atherosclerosis https://lnkd.in/dUYRCBR2

Trapping of apoB particles within the arterial wall is the root cause of atherosclerosis and the level of the apoB lipoproteins within plasma is the primary, but not exclusive, determinant of the number of apoB particles that will be trapped over time. Calcification is a histologic hallmark of advanced atherosclerotic disease. Thus, apoB causes atherosclerosis and CAC is a consequence of atherosclerosis

What is proptosis? A defining characteristic of thyroid eye disease (TED), proptosis refers to the protrusion of the eyes caused by swelling of the surrounding tissue. Learn more at: Bulging Eyes (Proptosis): What is It, Causes & Treatments https://lnkd.in/etdvDGxi #DidYouKnow? #TED #ThyroidEyeDisease

People living with scleroderma and the related scleroderma variant, Mixed Connective Tissue Disease, are at a higher risk of lung complications. Lung function tests serve as a screening method to detect individuals susceptible to developing serious lung conditions, including pulmonary fibrosis (lung scarring) or pulmonary hypertension (higher than normal blood pressure in the lungs). Here are some of our top tips to help guide you through! To learn more download our FREE brochure! https://lnkd.in/dfPdSUVb . . . . #Scleroderma #SclerodermaAwareness #Brochures  #LungFunctionTest #PulmonaryFibrosis #PulmonaryHypertension #Tips

#Goodmorninglinkedinworld........ #WorldSickleCellDay is observed on #19June every year to spread awareness about sickle cell disease, its preventive measures and their families go through. What is Sickle Cell Disease? Sickle cell disease or sickle cell anaemia is an inherited form of anaemia in which red blood cells are not able to carry adequate oxygen throughout the body. Let us tell you that in normal condition red blood cells are flexible and round. They move easily in the blood vessels. But in sickle cell disease or anaemia, the #redbloodcellsbecomerigid, sticky and become like sickle shape or crescent moon. As a result these irregular shaped cells get stuck in small blood vessels, which slow the flow of blood or block blood flow and reduce oxygen to reach the parts of the body. #sicklecells #anaemiacells #gethealthy #bepositive #phm

ZyVersa is developing Inflammasome ASC Inhibitor IC 100, which inhibits multiple inflammasome pathways (including NLRP3 and AIM2) to attenuate initiation and perpetuation of damaging inflammation that is pathogenic in numerous diseases. Learn more: https://bit.ly/483rPxT

😯"𝐂𝐎𝐍𝐓𝐑𝐀𝐈𝐍𝐃𝐈𝐂𝐀𝐓𝐈𝐎𝐍"👨⚕️ 💉 Ergotamine is approved for the treatment of 𝐌𝐢𝐠𝐫𝐚𝐢𝐧𝐞 𝐡𝐞𝐚𝐝𝐚𝐜𝐡𝐞𝐬. These ergot alkaloids act on 5-𝐇𝐓1 𝐫𝐞𝐜𝐞𝐩𝐭𝐨𝐫𝐬 located on intracranial blood vessels and cause vasoconstriction. 💉 Ergotamine is currently available 𝐬𝐮𝐛𝐥𝐢𝐧𝐠𝐮𝐚𝐥𝐥𝐲 and is most effective when used during the early stages of migraine. It is also available as an oral tablet or suppository containing both ergotamine and caffeine. 💉 𝐄𝐫𝐠𝐨���𝐚𝐦𝐢𝐧𝐞 𝐚𝐧𝐝 𝐃𝐢𝐡𝐲𝐝𝐫𝐨𝐞𝐫𝐠𝐨𝐭𝐚𝐦𝐢𝐧𝐞 𝐚𝐫𝐞 𝐂𝐨𝐧𝐭𝐫𝐚𝐢𝐧𝐝𝐢𝐜𝐚𝐭𝐞𝐝 𝐢𝐧 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬 𝐰𝐢𝐭𝐡 𝐚𝐧𝐠𝐢𝐧𝐚 𝐚𝐧𝐝 𝐩𝐞𝐫𝐢𝐩𝐡𝐞𝐫𝐚𝐥 𝐯𝐚𝐬𝐜𝐮𝐥𝐚𝐫 𝐝𝐢𝐬𝐞𝐚𝐬𝐞 𝐛𝐞𝐜𝐚𝐮𝐬𝐞 𝐭𝐡𝐞𝐲 𝐚𝐫𝐞 𝐬𝐢𝐠𝐧𝐢𝐟𝐢𝐜𝐚𝐧𝐭 𝐯𝐚𝐬𝐨𝐜𝐨𝐧𝐬𝐭𝐫𝐢𝐜𝐭𝐨𝐫𝐬.👍 𝐑𝐄𝐅𝐄𝐑𝐄𝐍𝐂𝐄,  https://lnkd.in/dhkJUjZf

No matter how you shape it, pulmonary fibrosis is a disease of the lungs. It goes by many names. Progressive Pulmonary Fibrosis is the new name for ALL forms of PF that progress over time. PF falls under the UMBRELLA - Interstitial Lung Disease or ILD. There are over 200 forms of ILD. MOST ILDs are or lead to pulmonary fibrosis. To learn more about pulmonary fibrosis or to join a support group, go to our website at the link on this graphic. #pulmonaryfibrosis #PF #PPF #IPF #rarediseaseday #BreatheSupport

Updates: 🫀⌛️Timing of Complete Revascularization with Multivessel PCI for Myocardial Infarction. 👉 👥 in hemodynamically stable condition with STEMI and multivessel coronary artery disease, immediate multivessel PCI was noninferior to staged multivessel PCI with respect to the risk of a composite of ☠️ from any cause, nonfatal AMI, stroke, unplanned ischemia-driven revascularization, or HF🏥 at 1 year . #NEJM https://lnkd.in/ggd8w2Ss

coronary artery disease is characterized by accumulation of fatty deposits (atheroma and plaque) and the inner most layer of coronary artery. It can cause a critical narrowing of the coronary artery lumen,resulting in a decreased coronary blood flow and inadequate supply of oxygen to the heart muscle. #snsinstitutions #snsdesignthinkers #designthinking