Vall d'Hebron Institute of Oncology (VHIO)’s Post

Nonalcoholic fatty liver disease can cause liver failure and cancer. Fortunately, it can also be reversed. Our Dr. John Smith shows how Sonic Incytes Medical Corp.’s Velacur imaging tool can help monitor thr progression of your liver disease. #liverhealth #fattyliver #nafld #gastroenterology

Dr. Michael Weinstein of Capital Digestive Care interviews Dr. Matthew Goldberg, who is medical director of Castle Biosciences, Inc. about TissueCypher - Barrett's Esophagus, a test to help gastroenterologists stratify risk for cancer in patients with Barrett’s Esophagus. Join Dr. Weinstein and Dr. Goldberg to hear about how this innovative test can help #gastroenterologists and #pathologists better identify those patients who are most at risk and provide the appropriate care to help prevent them from developing #esophagealcancer. #IndependentGI #Endoscopy

Perineural invasion (PNI) is the invasion of tumor cells around nerve fibers in the tissue. In pancreatic cancer, it is a marker of more aggressive disease. Despite its clinical importance, identification of #PNI in the microscopic evaluation of the surgical specimen in a challenging task that may be overlooked. To address this need, Sarah Borsekofsky, Rami Hagege and our research group recently developed an image analysis based algorithm that increases PNI detection accuracy and also reduces the time required for diagnosis. Importantly, to develop this tool we used a unique algorithmic approach that takes into account the way that pathologists think to make diagnoses. This approach enabled us to develop this robust algorithm based on a very small training set. We believe that this and other tools will improve the accuracy of diagnostic pathology and allow better patients care. Publication full access is available: https://lnkd.in/dhghvQZe Tel Aviv Medical Center Dov Hershkovitz #perneuralinvasion #pancreaticcancer #digitalpathology #artificialntelligence #AI https://lnkd.in/dhYxdm5f

📅 October 20th is the 𝐖𝐨𝐫𝐥𝐝 𝐎𝐬𝐭𝐞𝐨𝐩𝐨𝐫𝐨𝐬𝐢𝐬 𝐃𝐚𝐲: a day to raise awareness of this "silent" disease. 🩺Osteoporotic bone fractures are responsible for more hospitalizations than heart attacks, strokes and breast cancer combined in the US… 🦴𝟓𝟎% 𝐨𝐟 𝐫𝐞𝐩𝐞𝐚𝐭 𝐟𝐫𝐚𝐜𝐭𝐮𝐫𝐞𝐬 𝐜𝐨𝐮𝐥𝐝 𝐛𝐞 𝐚𝐯𝐨𝐢𝐝𝐞𝐝... Such figures are once more highlighting the urgency to better know this pathology and better cure it everyday! 👉 Our Team is daily exploring new treatments with its Partners and Customers for this disease, considered as a public health priority by more then 90% of specialists. Together in Preclinical Research! #osteoporosis #research #WorldOsteoporosisDay

We are happy to share our latest preprint in BioRxiv In short: Microglia, the macrophages of the brain, engulf other cells including neurons, in a process call phagocytosis. As microglial cells are hyperactive in Parkinson’s disease, we propose the use of immunotherapy to block this phagocytic capacity and avoid the elimination of dopaminergic neurons.  https://lnkd.in/dJJpTi8z

We are thrilled to announce that Professor George Yeoh has been funded for another year by Conquer Cystic Fibrosis , for his groundbreaking project titled "Establishing the utility of GCTM-5 as a biomarker for liver pathology in cystic fibrosis patients" This innovative research aims to develop a new blood test to detect early liver disease in CF patients, potentially transforming the way we diagnose and treat liver complications in those affected by cystic fibrosis. The project will include liver biopsy samples from across Australia and will significantly improve the ability to identify and manage liver disease before it advances too far. This one-year project aims to make a substantial impact on the lives of CF patients, offering hope for early intervention and better health outcomes. Join us in celebrating George's achievement and the strides being made in CF research! 👏 To read more about this research, follow the link: https://lnkd.in/gxFKK3qZ #CysticFibrosis #ResearchFunding #LiverDisease #BiomarkerResearch #CysticFibrosisAustralia #MedicalResearch #InnovativeHealthcare

MUST READ: Who’s Afraid of Early Cancer Detection? "Precision Health and Precision Medicine in jeopardy?" My 5Cent: Early detection without large reference databases may constitute a challenge, i.e. what is pathologically relevant and must be treated how. However, it is totally irreponsible not to explore the opportunity to hit as early as possible, if not today, maybe in the very near future. If we do not create the foundations for progress towars precision health and precision medicine, we act irresponsilble GRAIL Dana Goldman The Wall Street Journal Bob Ragusa Aashima Gupta Jeff Huber Franz Och #Innovation #Medicine #DrugDiscovery #Diagostics #LiquidBiopsy #PrecisionMedicine #PrecisionHealth #Prevention #Healthcare #Science #Research #Biomarkers #MultiOmics #Biotech #Treatment https://lnkd.in/dssUejZe

Aging-US recently #published this #research paper: “Highly multiplexed immune profiling throughout adulthood reveals kinetics of lymphocyte infiltration in the aging mouse prostate." @university-of-california https://lnkd.in/ebz8K5M9 #aging #prostate #researchpaper #openaccess #openscience #peerreview #journal #publication #inflammation #agingshort #video

Circulating cell-free DNA (cfDNA) has become an attractive #noninvasive disease #biomarker, as it can be found in different body fluids, both in healthy and not healthy individuals. The rapid development of new molecular techniques is promoting the identification of cfDNA, holding the key to minimally invasive diagnostics, improving disease monitoring, clinical decision, and patients' outcome. cfDNA has already given a huge impact on prenatal medicine - known as #NIPT, and it could become, the standard of care also in other fields, from #oncology to #transplant medicine and #cardiovascular diseases. #Cell-free #DNA; #fetal DNA; #Circulating #tumor #DNA; #liquidbiopsy, #Oncogenetics, #organtransplant #cfDNA #DNA #sensitivity #biomarker #donor #genetic #plasma

Is the Precision Medicine just a distant concept? Precision Medicine has already revolutionized cancer treatment. By analyzing the genetic mutations of a patient's tumor, doctors can pinpoint targeted therapies . However, what about ·        Pharmacogenomics, ·        Rare Diseases ·        Cardiovascular Health ? There are still only a handful of healthcare facilities that are taking full advantage of precision medicine. As we continue to bridge the gap between research and practical applications, What aspects of your healthcare job do you believe could be transformed by Precision Medicine? #precisionmedicine #healthcareInnovation #genomics #patientcare #medicaladvancements