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A common assumption is that for most people, both physical and cognitive function peak in their 20s before declining throughout the adult lifespan. As an undergraduate at University of California, Berkeley, Dr. K. Warner Schaie began to challenge this assumption. After having retirees take a cognitive test that was designed for children, he discovered that adults performed better than high school students. Schaie’s curiosity gave rise to the Seattle Longitudinal Study (SLS), one of the most extensive psychological research studies of cognitive health and aging ever conducted. From 1956 to 2012, Schaie tested and added a new cohort of participants every seven years. For more than 30 years, Schaie and his wife, Sherry Willis, PhD, a research professor at the UW Department of Psychiatry and Behavioral Sciences, researched cognitive development and aging at Penn State University, returning to Seattle to conduct SLS testing. “Drs. Schaie and Willis demonstrated that cognitive functioning isn’t as simple as an early peak and a guaranteed decline as we age,” says Jürgen Unützer, MD, MPH, MA, chair of the Department of Psychiatry and Behavioral Sciences, University of Washington. “They helped to combat ageist attitudes, showing us that there are many people who stay sharp in their old age.” Schaie passed away in February 2023 at the age of 95, he left a substantial body of work and a philanthropic commitment to create an endowed chair in the UW Department of Psychiatry and Behavioral Sciences. Today, the study’s impact lives on through the work of researchers like Jeffrey Iliff, PhD, who studies the relationship between sleep and cognitive impairment or dementia. “As a society, we are just beginning to understand risk factors for dementia,” says Dr. Unützer. “A lot of research is focused on people who have dementia, but we need to learn about what makes the brain resilient to risk factors by studying people who have them and yet haven’t developed dementia. That is one opportunity SLS data creates.”

What a Decades-long Study Teaches Us About Brain Health and Aging

What a Decades-long Study Teaches Us About Brain Health and Aging

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