Scribe Therapeutics’ Post

Scientists have been pushing the boundaries of science with innovative research methods, and single-cell analysis is no exception. The ability to edit a cell’s genome with precision has transformed how scientists create research models, producing therapeutics, and treating diseases. Namocell's fast, gentle and easy single cell isolation enables high throughput cell cloning after genome editing and engineering, with better clonal outgrowth owing to the ultra-low sorting pressure. Learn more about the advantages of Namocell: https://lnkd.in/gzQhnMx #Cellengineering #CRISPR #singlecellanalysis #Namocell #iPSC #CRISPRcloning #iPSCclone #SingleCellDispenser

InVitria, Inc. is attending #ASGCT24 in Baltimore! We will be located at Booth 131. Stop by to learn how our sustainable recombinant technology has been implemented by #celltherapy and #genetherapy developers to enhance biomanufacturing and final formulation! Connect with us through the event meeting portal to schedule a meeting. Team Members attending include: Andrew Hamann, PhD, Mark Stathos, Ph.D., Jake Hanks, Marcus Curl, Elliott Renft, Colin Odishoo, and Scott Deeter. Here's how InVitria's innovations contribute to success: Sustainability A steadfast focus on reducing the environmental impact and ensuring a sustainable and ethical supply of critical components for clinical applications. Safety and Quality Our commitment to animal-free components significantly reduces the risk of contaminants and ensures higher manufacturing consistency. Performance Enhanced cell growth, productivity, and product yield, facilitating faster and more efficient production cycles. We believe these solutions are pivotal to a future where cell and gene therapy achieve their promise for patients. They are not just a step towards more ethical and sustainable practices but also a leap towards more reliable and efficient therapeutic production. #SustainableSolutions #CellTherapies #GeneTherapies #AnimalFree #CharmCity

If you are one of those scientists willing to expand your knowledge in your spare time join this summer series from Ncardia. In this series you will learn how human iPSC technology is revolutionizing drug discovery, gene therapy and regenerative medicine. By following this series you will also get additional resources related to the topics of the 4 webinar sessions. Easy at your hand! #webinar #learning #stemcell

What makes Aqtual different?   Our efficient, single-analyte platform is the first of its kind to measure regulatory active chromatin. This approach enables us to identify an entirely new category of organ-specific DNA signatures. Evaluating protein regulation, epigenetics, and transcriptomics through a routine blood test offers new clinical applications in almost every major disease area. Learn more about our technology: https://lnkd.in/ef_Jyree #fAqtual #Aqtual #RA #ChronicConditions

Adenine base editors, such as ABE7.10, enable programmable C•G to T•A point mutations, but editing efficiencies can be low at challenging loci in primary human cells. 🧬 Discover how Beam Therapeutics leveraged DNA variant libraries of adenine base editors, synthesized by Ranomics, to evolve ABE7.10 into the ABE8s with superior editing performance 👉 https://lnkd.in/gAJCq7TJ #beamtherapeutics #crisprcas9 #geneediting #genetherapy #geneticengineering #dna

#SDDS2024 Ready for the Stanford Drug Discovery Symposium Day 2 with SPARK Finland and KAJO Neurotechnologies, looking forward to discuss drug development with human Parkinson’s disease cell model

Looking forward to #SLAS2024 where we will be showcasing our ioCRISPR-Ready Cells™️ products. Our poster presentations will include data from two products - the recently launched CRISPR-Ready ioGlutamatergic Neurons™️ and the next product in the range - CRISPR-Ready ioMicroglia™️. Find out more in the press release. 👇📰 https://hubs.ly/Q02j60Vz0 ioCRISPR-Ready Cells are iPSC-derived human cells containing a constitutively-expressed Cas9 nuclease. They arrive ready-to-use and with simple protocols, allowing high gene knockout efficiencies and functional experimental readouts in a physiological relevant cellular model in days, significantly reducing experimental timelines. #CRISPR #Research #DrugDevelopment #SynBio #BioEngineering

Our CEO, Tuyen Ong, MD, MBA, was featured in the latest episode of the Biotech2050! Hear Tuyen dive into his career journey and share insights on the importance of cross-disciplinary expertise and resilience in transforming the future of #GeneticMedicine.

📰 Pectins and The Health Effects 🔍 Pectin, a #plant -derived polysaccharide, possesses #\immense technological and biological application value. Several variables influence pectin’s physicochemical aspects, resulting in different fermentations, interactions with receptors, and other functional properties. Some of those variables are molecular weight, degree of methylation and blockiness, and monosaccharide composition. #cancer #cell cytotoxicity, important fermentation-related byproducts, immunomodulation, and technological application were found in cell culture, animal models, and preclinical and clinical assessments. 👨🎓 Lucas de Freitas Pedrosa, Karen Rebouças Nascimento, Caroline Giacomelli Soares, et al. 🔗 https://lnkd.in/gDiE48jt Plants MDPI Plant Based News 👇 Figure 1. Schematic depiction of variable pectin molecules and their respective region of higher biological activity.

#Article now available! #AAV & #lentiviral vector titer determination: past, present, & future In this article, Mark White (Associate Director, Biopharma and Translational Product Marketing, Digital Biology Group, Bio-Rad Laboratories), John Bechill (Principal Scientist, BioProcess Group, Modalis Therapeutics), and Peng Wang (Senior Scientist, #ViralVector Analytical Team Lead, Lonza) discuss the need for accurate viral titer determination, traditional approaches to measuring viral titer, and the field’s trajectory into the future. Read this article to: • Review the traditional methods used for measuring viral titer for both AAV and LV #vectors • Explore new analytical technology to address the limitations of these traditional methods • Gain insight into how regulators’ opinions and expectations have evolved with regard to methods for accurate viral titer determination • Discover the key emerging analytical methods for AAV and lentiviral vectors Read at your convenience below: