Remepy’s Post

📢 Success Story alert Researchers used #moleculardynamics and #machinelearning to understand allosteric inhibitors' effects, enabling the design of safer #NLRP3 inhibitors. In this #successstory, Francesca Spyrakis, Emanuele Casali, Stefano Serapian, Eleonora Gianquinto, Matteo Castelli, Massimo Bertinaria and Giorgio Colombo highlight NLRP3 inflammasome as a target for treating neuroinflammation in diseases like long #COVID, #Alzheimer's, and #Parkinson's. 📜 Read the full story: https://lnkd.in/dTPVE4r7 EBRAINS Forschungszentrum Jülich CSCS Barcelona Supercomputing Center CINECA

🧠 Today is World Brain Tumor Day, a day to raise awareness, spread hope, and stand in solidarity with all those affected. Let's honor the strength of patients, families, and medical professionals who fight this battle every day. Together, we can support research, inspire courage, and work towards a cure. 💙 #WorldBrainTumorDay #BrainTumorAwareness #Hope #Strength #SupportResearch 4o

The research gateway is already booming with content to kick off the second day at ESC 2023. Lots of content on myocardial infarction, heart failure and atrial fibrillation - and how fibrosis is involved. I love this format of data being presented, with participants who work with everything from early in vitro experiments to late-stage clinical development engage in discussions. #esccongress2023

A Sensory trick refers to a fascinating, characteristic, voluntary maneuver that ameliorates dystonia severity. For most people with cervical dystonia, it can be something as simple as touching the lower part of their face or the back of their head. We demonstrate and quantify its therapeutic benefit by analyzing data on ~1000 subjects with cervical dystonia. Implications for interventional studies? #dystonia #clinicaltrials #clinicalresearch

Some very encouraging results for my friends at U: The Mind Company following a study testing out the novel concept of amplitude modulated Transcranial Pulsed Current Stimulation (am-tPCS) to treat symptoms of Parkinson's Disease. Overall, an estimated 80.0% tremor reduction was observed via video analysis, and a reduction of 73.5% was observed in UPDRS. The study suggests that am-tPCS is safe and efficacious in the PD population in comparison to other stimulation waveforms. Congratulations 🧠 Mohammed (Mo) Abouelsoud, David Mishelevich, M.D., Ph.D. Jeff Spitzner, PRINCE KAZADI and all involved in the study. More research to follow..... #parkinsonsdisease #noninvasive #brainstimulation

NEWSLETTER SPRING 2023 | Many of you wish to hear from other dystonia patients and how they manage their dystonia. You also want to have information on treatments and research. We have therefore decided to start...(Read more on the blog linked int his post).

I’m happy to share our #review entitled: “Role of expectations in clinical outcomes after deep brain stimulation in patients with Parkinson's disease: a systematic review” 🎉 Full text: https://lnkd.in/eyQyfpEa

Discover how blood-based tests, such as Quanterix's Simoa p-Tau 181 assay, could support Alzheimer's treatment access post-FDA approval of Leqembi. Insights from CEO Masoud Toloue and MM+M: #Alzhimers #Biomarkers

Alzheimer's researchers are working tirelessly to explore innovative approaches to treat both the symptoms and underlying disease process. It's inspiring to see people of color like Paul S. Yong, MD advance this research using innovative and noninvasive approaches. #AlzheimersResearch #InnovativeApproaches #leaders https://lnkd.in/gdQfSskA

Exciting research from the University of the Basque Country and Biobizkaia reveals a promising method for predicting cognitive decline in Parkinson’s patients using retinal thickness. Thinner retinal layers correlate with disease progression, offering valuable insights for improved monitoring and treatment. This non-invasive approach shows great potential for identifying at-risk patients and enhancing clinical outcomes. The study's findings could revolutionize the way we track neurodegeneration in Parkinson's disease. #Parkinsons #Neurodegeneration