PolTREG S.A.’s Post

#ACROHighlights [Featured Product] 🎯 Targeting Autoimmune Diseases: OX40/OX40L Unlocking the potential for innovative therapies, OX40 and OX40L (OX40 Ligand) have emerged as promising targets in autoimmunity. Together, they activate T cells, amplifying cytokine expression and offering new avenues for treatment. Extensive research showcases the impressive therapeutic efficacy of blocking OX40/OX40L in systemic lupus erythematosus, atopic dermatitis, and inflammatory bowel disease. 🔬 Supercharge Your R&D with our Advanced OX40/OX40L Proteins! 🔗https://lnkd.in/gGr-adYt #Autoimmune #ImmuneCheckpoint #OX40 #OX40L #Innovation #Biotech

Developing therapies to degrade free cholesterol With its first-in-class Cholesterol Degrading Platform (CDP), Repair Biotechnologiesis tackling the root cause of many difficult-to-treat age-related diseases. https://lnkd.in/ephAB5Ex Co-founded in 2018 by Reason, a patient advocate, and Bill Cherman, a biotech investor, Repair Biotechnologies springs from the growing longevity movement and aims to tackle one of medicine’s fundamental questions: how can we intervene to repair the biological damage of aging and thereby reverse the progression of diseases of aging? #longevity #aging #partnering #repairbiotechnologies #biopharmadealmakers

Prof. Piotr Trzonkowski, Chief Executive Officer at PolTREG explained the great potential of cell therapies and PolTREG’s unique achievements in treating autoimmune diseases, in an interview with Polish business newspaper Gazeta Giełdy i Inwestorów „Parkiet”. Some highlights from the interview: ✅ PolTREG just announced the results from a long-term study in treating type 1 diabetes, demonstrating safety and efficacy of up to 12 years after PolTREG began administering its therapies. No other company in the world has such long-term results. The study is due to be published at a conference in September. ✅PolTREG has the most advanced pipeline of Treg candidate therapies. It is the only company developing all modalities of Treg therapies for auto-immune disease: from polyclonal T-cells to several types of engineered T-cells, autologous and allogeneic.   ✅ PolTREG has a unique ability to manufacture cell therapies in its proprietary GMP-certified facility, where it can produce 1,500 therapies per year, which can be shipped across Europe within 24 hours. Watch the full interview (in Polish): https://lnkd.in/dqRy-utV #biotech #biotechnology #celltherapy #cellandgenetherapy #autoimmunedisease #diabetes #type1diabetes

BIOTECH NEWS: Tourmaline Bio has initiated the clinical development of TOUR006 for the treatment of cardiovascular diseases with the first patient dosed in the Phase 2 TRANQUILITY trial. This milestone marks an important step in realizing the promise of IL-6 as a therapeutic target for treating a wide range of diseases with the potential to dramatically improve the lives of patients and transform standards of care. Learn more about today's news: https://bit.ly/3WIRuJS #biotechnology #drugdiscovery #interleukin6

#ACROHighlights [Featured Product] 🚀 Unlock the Future of Autoimmune Disease Therapies 🚀 Cytokines are key players in autoimmune diseases (AID). Targeting these inflammatory mediators opens doors to more effective treatments. Dive into our latest article exploring the link between cytokines and conditions like ankylosing spondylitis, psoriatic arthritis, and systemic sclerosis. Discover our comprehensive range of recombinant cytokines and receptors, designed to propel your autoimmune drug development efforts. 🔗 https://smpl.is/9ezwo #Innovation #Biotech #DrugDevelopment #Healthcare #LifeSciences

Human Leukocyte Antigens (HLAs) are vital proteins in our cells that help our immune system identify the good from the bad. They're like your immune system's VIP pass! Ever wondered how knowing your HLA type can benefit you? Well, it's all about being proactive! If you're HLA-B27 positive, it can help with quick diagnosis and management of conditions like Ankylosing Spondylitis, Juvenile Rheumatoid Arthritis, Anterior Uveitis, and Reactive Arthritis. Early detection can lead to a better quality of life. HLA-B27 RT-PCR detection kit from NeoDx detects Exon 2/Exon 3 in Human Leukocyte Antigen B27 in whole blood. #genetictesting #ankylosingspondylitis #health #inflammatoryconditions #diagnosis #arthritis #rtpcr #screening #healthcare #autoimmune #genetics #rheumatoidarthritis #autoimmunediseaseawareness #ulcerativecolitis #startupindia #startup #diagnostics #laboratory #tests #medical #healthsolutions #laboratory #research #science #biotechnology #molecularbiology

In the third article of our educational series on fibrosis, we look at kidney fibrosis, and the impacts it can have on a person’s health, and why treatments like AdAlta Ltd’s AD-214 are needed. Click below to learn more. #fibrosis #biotech #kidneyhealth

𝗧𝗵𝗲 𝗿𝗼𝗹𝗲 𝗼𝗳 𝗛𝗠𝗚𝗕𝟭 𝗱𝗶𝘀𝘂𝗹𝗳𝗶𝗱𝗲 𝗳𝗼𝗿𝗺 𝗶𝗻 𝗮𝗹𝗰𝗼𝗵𝗼𝗹-𝗮𝘀𝘀𝗼𝗰𝗶𝗮𝘁𝗲𝗱 𝗹𝗶𝘃𝗲𝗿 𝗱𝗶𝘀𝗲𝗮𝘀𝗲𝘀 A recent study has highlighted the significant role of the disulfide form of HMGB1 protein in liver pathologies related to excessive alcohol consumption. 𝗜𝗻 𝗛𝗠𝗚𝗕𝗶𝗼𝘁𝗲𝗰𝗵 𝘄𝗲 𝘀𝗲𝗹𝗹 𝗮𝗹𝗹 𝗼𝗳 𝘁𝗵𝗲 𝗛𝗠𝗚𝗕𝟭 𝗳𝗼𝗿𝗺 𝘂𝘀𝗲𝗱 𝗶𝗻 𝘁𝗵𝗶𝘀 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵. Discover our shop: https://lnkd.in/d5AUsre9 𝗥𝗲𝗮𝗱 𝘁𝗵𝗲 𝗳𝘂𝗹𝗹 𝗮𝗿𝘁𝗶𝗰𝗹𝗲 𝗮𝗯𝗼𝘂𝘁 𝘁𝗵𝗲 𝘀𝘁𝘂𝗱𝘆: https://lnkd.in/d4hUEgYf HMGBiotech Srl can provide comprehensive information to facilitate informed decision-making for researches with HMGB1. 𝗖𝗼𝗻𝘁𝗮𝗰𝘁 𝘂𝘀 𝗳𝗼𝗿 𝘆𝗼𝘂𝗿 𝗽𝗿𝗲-𝘀𝗮𝗹𝗲𝘀 𝗾𝘂𝗲𝘀𝘁𝗶𝗼𝗻𝘀 𝗮𝗯𝗼𝘂𝘁 𝗛𝗠𝗚𝗕𝟭: https://www.hmgbiotech.eu/ University of Illinois Chicago, GE Xiaodong, HUI HAN, Romain Désert, Sukanta Das, Sai Santosh Babu Komakula Ph.D., Dipti Athavale, M Pharm, PhD, Natalia Nieto Villa #chemokine #biotechnology #immunotherapy #immunosurveillance #immunesystem, #clinicalresearch #medicine #diagnostic #immunology #medicalresearch #protein #biomedicalscience #therapy #researchers #Hepatitis #inflammatory #liver #liverdiseases

Exciting news! My newest article written together with Sander Delwig has been published today. The article is a feasibility study and impact study about repurposing human leukocyte antigen (HLA) genotype data. HLA genotyping data is already routinely used to identify kidney donor matches but the data can be reused to prevent drug hypersensitivity reactions. Special thanks to all co-authors, especially my promotor Henk-Jan Guchelaar. Check out the article to learn more! https://lnkd.in/eQhc8kyG #healthcare #research #genotypedata #HLA

Adicet is pleased to announce that the FDA has granted Fast Track Designation to ADI-001 for the potential treatment of relapsed/refractory class III or IV lupus nephritis! The FDA’s decision to grant ADI-001 Fast Track Designation for lupus nephritis underscores the urgent need for new therapies for this chronic disease. Advancing #research is critical to the development of novel therapies for people living with #lupus. Learn more about Adicet’s #clinicaltrial in lupus nephritis at https://lnkd.in/esC4winc To see the full announcement, click here: https://lnkd.in/gmzbgGyj #celltherapy #gammadelta #CART #autoimmune #clinicaltrials #biotechnology #patientcare #clinicaltrialparticipation