ONI’s Post

Just this time we are having Fluorescence Thursday instead of the usual #FluorescenceFriday, so that we can wish you all happy 4th of July with a beautiful display of #ExtracellularVesicles (EVs). These single EV were stained using our #EVProfiler2 kit and imaged on the #Nanoimager with #AutoEV. This approach allows the user to gain insights on the size and shape of their EVs, as well as biomarker distribution. We wish our friends and colleagues a happy 4th of July! For our team across the pond, we wish you a good election day, choose well and make your voice heard.

🔬 Join us on an exploration into the realm of extracellular vesicle (EV) research with Colbie Chinowsky, PhD, an Applications Development Scientist at ONI! 🌟 In this interview, Colbie discusses her journey into EV studies, the key questions researchers are tackling, and the future direction of this exciting field. Read the interview here ➡️ https://hubs.li/Q02F7Tdp0 #CuriousMinds #ExtracellularVesicles #EVResearch #ScientificInnovation #ONIScientists #PhDJourney #MolecularBiology #ScientificResearch #FutureOfScience #BioResearch #LabLife #ScienceInterview

🌟 Meet George Owen, Corporate Development Associate at ONI! 🌟George embodies our core value: "We succeed when our customers meet their goals." 🤝 George believes impactful scientific discovery thrives on passionate collaboration and the right tools. Here's what George had to say about our new corporate value: "Impactful scientific discovery comes about when passionate people are able to collaborate and tackle the most challenging problems with the best tools for the job. At ONI, our customers are our collaborators, and it’s our responsibility to understand the challenges they face in their work and how we can help overcome them. We use this knowledge to build products which deliver high quality, meaningful results for the user. When our customers succeed, we succeed, and we are committed to ensuring this, every single time." 🚀#CustomerSuccess #Collaboration #ScienceImpact

The month of June was very eventful in the history of #microscopy. For today's #FluorescenceFriday we celebrate another chapter in the #HistoryOfScience, and mark 83 years for the first introduction of a fluorophore-conjugated antibody, which is now an indispensable tool in light microscopy. More than a decade before the elucidation of the double helix structure of #DNA, and years before molecular cloning became widely common, Albert Coons and his colleagues from Harvard University used chemistry to conjugate a fluorescent dye to antibodies they extracted from the serum of an inoculated rabbit. The scientists indeed tried to use the fluorescent antibodies for tissue #imaging, however, they failed, due to the overlap between the wavelength of the fluorophore and the wavelength of the tissue autofluorescence. Nonetheless, working on a compatible fluorescent antibody was already "in progress" at the time of publishing this historic paper in 1941. Today, the 28th of June, also marks the 112th birthday of Albert Coons, the scientist who pioneered the field of #immunofluorescence. Read the historic paper: https://hubs.li/Q02BBLt-0 In the image here is a #dSTORM image which used fluorescently-labeled antibodies against the mitochondrial protein Tomm20 in green and the ER protein CLIMP63 in magenta, taken using the #Nanoimager.

⭐ It's that time again! ⭐ Welcome back to ONI's weekly A-Z of Super-Resolution! Today, join us for a spotlight on "V" for Voronoi Diagram🔬 🔍 A Voronoi diagram is a mathematical method for segmenting planes into cells, where each cell is defined by the distance from a single point called a "seed." The borders of each cell represent an equal distance between one seed and another. In super-resolution microscopy, Voronoi diagrams can be used to determine the localization of labeled targets. Missed the Super-Resolution Word of the Week from the past weeks? 🤔 Catch up now! https://hubs.li/Q02DfV2D0 #CuriousMinds #SuperResolution #Microscopy #Nanoimager #VoronoiDiagram #DataSegmentation #CellLocalization

We are wishing you lots of exciting results with your new #Nanoimager!

⭐As ONI has evolved, our core values have expanded and strengthened. We are excited to announce our newest core values that guide us forward:⭐ We Find a Way 🗺️ We are proactive, collaborative problem-solvers who prioritize simplicity in our solutions. We Accelerate Discovery 🚀 We create workflows that empower impactful science and uncover hidden insights at the molecular level. We Succeed When Our Customers Meet Their Goals 👩🔬 We are dedicated to providing a high-quality experience, working closely with our customers to help them achieve outstanding results. Together We Grow 🌱 With curious minds, we embrace the roles of both teachers and students, leveraging diverse experiences to tackle complex challenges. We Set a High Bar ⛰️ We take ownership and are ambitious about the future of ONI, always striving for excellence.

With a great scientist like you, Laura Woythe, PhD, we are sure that any experiment could work, rain or shine!

Ready for another round of What's in the Image? 🔬🕵️♀️ Check out today's beautiful 2-color #dSTORM image! Can you tell what's under the lens of our talented scientists this time? #SMLM #SuperResolution #Nanoimager #imaging #microscopy #microscope #CellBiology #CellBio #biology #research #organelle