Octane OC’s Post

From the boundless potential of human fat for regenerative solutions emerges liposmart®, a groundbreaking concept and system. 💡 We've merged the understanding that stem cells' regenerative power thrives within their microenvironment (the stromal vascular niche) with the ability to create a Unified Fluid Adipose Tissue (UFAT) derivative. This innovative product encapsulates all the biophysical properties of original fat tissue in a single, readily available solution.🌱 Unlock the full potential of regenerative medicine with liposmart! #liposmart #regenerativesolutions #medicalinnovation #RegenerativeSolutions #stemcells #medicalinnovation

From the boundless potential of human fat for regenerative solutions emerges liposmart®, a groundbreaking concept and system. 💡 We've merged the understanding that stem cells' regenerative power thrives within their microenvironment (the stromal vascular niche) with the ability to create a Unified Fluid Adipose Tissue (UFAT) derivative. This innovative product encapsulates all the biophysical properties of original fat tissue in a single, readily available solution.🌱 Unlock the full potential of regenerative medicine with liposmart! #liposmart #regenerativesolutions #medicalinnovation #RegenerativeSolutions #stemcells #medicalinnovation

#citation New research from The Ohio State University Wexner Medical Center published in The Journal of Clinical Investigation reveals that NaV1.6 dysregulation within myocardial T-tubules by D96V calmodulin enhances proarrhythmic sodium and calcium mishandling. ✅ The study, conducted by Tarasov et al., found that D96V-CaM induced a proarrhythmic late Na+ current (INa) by impairing inactivation of NaV1.6, but not the predominant cardiac NaV isoform NaV1.5. The resulting late INa promoted aberrant Ca2+ release and prolonged APD in myocytes, leading to LQT and ventricular tachycardia in vivo 1. ✅ The research provides new insights into the mechanisms underlying arrhythmias and could lead to new therapeutic targets for treating arrhythmias 2. ✅ The study implicates NaV dysregulation within transverse (T) tubules in D96V-CaM–associated arrhythmias. D96V-CaM promoted arrhythmias by dysregulating LTCCs and NaV1.6 within T-tubules and thereby facilitating aberrant Ca2+ release 1. This research provides new insights into the mechanisms underlying arrhythmias and could lead to new therapeutic targets for treating arrhythmias. ⭐ Read more here: https://lnkd.in/dbnrhACY Cyagen is proud to be part of this research with our CKI mouse models. Check out our TurboKnockout® Humanized and Knockin Mice: https://lnkd.in/dPkfib96 #biotech #biotechnology #bioscience #science #bio #researchpaper #scienceandtechnology #newresearch #biotechnologies

The Katemed team congratulates and acknowledges the initiative of Allmedica in partnership with BPB MEDICA™ in this excellent opportunity for learning and knowledge exchange, especially in the area of fat harvesting for subsequent orthopedic use. Simplifying and making procedures faster, more practical, and less painful is crucial for enhancing patient experience and treatment outcomes. These improvements can have a significant impact on the effectiveness of procedures and patient satisfaction. #regenerativemedicine  #surgicalinnovation  #lipoaspiration  #stemcells #CartilageRepair  #Arthritis #BiologicTherapy #ArthritisAwareness #Osteoartrite #InovaçãoMédica #SaúdeArticular #Artroscopia  #Hospital #orthobiologics #Portugal #LipoStemDuo  #Katemed  #ortopedia

I am thrilled to lead in the change to assist families gain access to medical advancements that can help secure their families health in future. The potential of stem cells for groundbreaking improvements in regenerative therapy and medical research is amazing and ever evolving. Together, we are shaping a healthier, more resilient future. 🌱 Read about the vital role of stem cells in modern medicine in our article.

A detailed protocol for labeling IL-22 mRNA-loaded lipid nanoparticle (LNPs), administering them orally to mice, and visualizing their biodistribution in the gastrointestinal tract using IVIS spectrum imaging. https://lnkd.in/gqiqu38Z 🔹 Delivers IL-22 mRNA to ulcerative colitis sites using LNPs. 🔹 Uses fluorescent DiR dye for imaging in the gastrointestinal tract. 🔹 Employs IVIS spectrum for detailed imaging. Work by Rabeya Jafrin Mow, Anand Srinivasan, Eunice Bolay, Didier Merlin, and Chunhua Yang at Georgia State University and Yale University. Reviewed by AGNIESZKA ZIENKIEWICZ and Riddhi Jani, PhD. Explore publishing with Bio-protocol at https://lnkd.in/gR3QGYz6. #openaccess #reproducibility #lifesciences #research #molecularbiology

My colleague, Margaret (Mache) Cruz, presented our research on "Facile Extraction of α2 Beta Casein Milk-Derived Extracellular Vesicles and Their Impact on C2C12 Cell Migration" at BMES. This research highlights how milk-derived EVs can enhance cell migration in C2C12 murine myoblasts, showcasing their potential in therapeutic applications for tissue healing. We are proud of our team's dedication to advancing biomedical engineering. #BiomedicalEngineering #ResearchInnovation #ExtracellularVesicles #TissueEngineering #CMUEngineering

Shaping the Future of Healthcare: Our Vision at Accelerated Biosciences At Accelerated Biosciences, our vision is to revolutionize patient care through the innovative application of human Trophoblast Stem Cells (hTSCs). We believe in a future where regenerative medicine is not just an option, but a fundamental pillar of healthcare. Our groundbreaking research into hTSCs holds the promise of developing therapies that can repair damaged tissues, regenerate organs, and ultimately, save lives. These cells, known for their pluripotency and immune-privileged status, are key to overcoming some of the biggest challenges in treating chronic and degenerative diseases. We're driven by the potential to not only extend life but to enhance the quality of life for patients worldwide. Our work is about more than just scientific achievement; it’s about creating meaningful, lasting changes in the healthcare landscape. As we continue to push the boundaries of what's possible in medicine, we invite you to join us on this journey. Follow our progress, engage with our discoveries, and be part of a community that is transforming the future of health, one cell at a time. #FutureOfHealthcare #VisionaryLeadership #RegenerativeMedicine #StemCellInnovation #TransformingLives

🌐 Explore groundbreaking research in Cryptococcal meningoencephalitis treatment, featuring the LUNA-FL Dual Fluorescence Cell Counter by Logos Biosystems. 🚀 Uncover breakthroughs in combating Cryptococcal meningoencephalitis (CM), a perilous condition caused by the fungus Cryptococcus. 🍄 👩⚕️👨⚕️👍 The LUNA-FL Dual Fluorescence Cell Counter was instrumental for clinicians at the The National Institutes of Health Clinical Center, revealing the efficacy of tocilizumab in reducing post-infectious inflammatory response syndrome after CM. But it doesn't stop there! The LUNA-FL goes beyond conventional cell counting, providing precise insights into the impact of antifungal therapies on fungal lysis-induced autoimmune damage. ☠️ Elevate your research with unparalleled accuracy and efficiency. ☞ https://ow.ly/6pF650PZqXK Embrace the future of research—where every cell counts! Curious to know more? We're thrilled to provide additional information or schedule a personalized demo to showcase how the LUNA-FL can elevate your research endeavors. Contact us today and embark on a journey of scientific discovery! 🧪🔍 ☞ https://lnkd.in/eeiKuc8e #bucherbiotec #lifesciences #research #Switzerland #cellcount #biotech #innovation #NIH #ScientificInnovation #CuttingEdgeTech #meningoencephalitis

𝗜𝗻𝘃𝗲𝘀𝘁𝗶𝗴𝗮𝘁𝗶𝗻𝗴 𝘁𝗵𝗲 𝗲𝗳𝗳𝗲𝗰𝘁 𝗼𝗳 𝗝𝗮𝘄 𝗣𝗲𝗿𝗶𝗼𝘀𝘁𝗲𝘂𝗺-𝗱𝗲𝗿𝗶𝘃𝗲𝗱 𝗠𝗦𝗖 (𝗝𝗣𝗖) 𝘀𝗲𝗰𝗿𝗲𝘁𝗼𝗺𝗲𝘀 🔍👨⚕️ After culturing their JPCs in 10% HPL supplementation, researchers from the Universitätsklinikum Tübingen investigated the effect of JPC secretomes on CD4+ Monocyte-derived Dendritic Cells (MoDCs). Previously, the researchers had presented evidence that JPCs were able to induce a more immature phenotype of dendritic cells, leading them to look into the effects of their secretomes to further expand knowledge of JPCs' immunoregulative functions. In their paper¹, the researchers concluded that "[Tissue Engineering] constructs colonized with JPCs will probably not induce an inflammatory immune reaction after implantation... facilitating favorable integration of the implants into the surrounding bone tissue". 🦴 1. Cen, W., Umrath, F., Salgado, A. J., Reinert, S. & Alexander, D. Secretomes derived from osteogenically differentiated jaw periosteal cells inhibit phenotypic and functional maturation of CD14+ monocyte-derived dendritic cells. Front. Immunol. 13, 1024509 (2023). https://lnkd.in/eeUegNGM #dendriticcells #regenerativemedicine #immunoregulation #cellculture #bone #humanplateletlysate #hpl #tubingen #immune #PLBS