Moana Ji’s Post

https://lnkd.in/gXeMN7YW Article title: Bilateral Painless Testicular Enlargement: An Unusual Presentation of Sarcoidosis and a Literature Review   Author(s): Enver Simsek; Tulay Simsek; Meliha Dermiral; Mustafa F Acikalin   Journal: International Journal of Clinical Endocrinology and Metabolism   Journal ISSN: 2640-7582 Background: Sarcoidosis is a systemic inflammatory disease characterized by non-caseating epitheloid granulomas; whereas it usually involves the lungs and lymph nodes, genitourinary involvement is extremely rare. For this reason, no consensus regarding the diagnostic and management options for testicular sarcoidosis has been reached. #Children #Turkish #GenitourinarySarcoidosis #TesticularSarcoidosis #TesticularMasses #EndocrineGlands #Hormones #HormoneMetabolism #StructureAndPhysiochemicalProperties #HormonalReceptors #SignalingMechanisms #HormoneRegulatedGeneExpression #IntracellularSteroidAndLipidMetabolism #BoneAndMineralMetabolism #Infertility #Peertechz #PeertechzPublications #SexualDifferentiation #Puberty #PediatricEndocrinology #EndocrinePharmacology #MolecularEndocrinology #GastrointestinalEndocrinology #Neuroendocrinology #ComparativeEndocrinology #CardiovascularEndocrinology #ReproductiveEndocrinology

https://lnkd.in/esHdVYbK Article title: Teriparatide in a patient with severe osteoporosis, hypoparathyroidism and thalassemia major   Author(s): Graziani A; Cannito M; Putti MC; Camozzi V   Journal: International Journal of Clinical Endocrinology and Metabolism   Journal ISSN: 2640-7582 Abstract: β-Thalassemia Major (TM) is a form of beta-thalassemias. TM complications include, among others, osteoporosis, whose frequency, among TM patients, varies from 13.6% to 50%. The overall etiological mechanisms of TM-related osteoporosis remain unclarified. The primary approach to osteoporosis in patients with TM is the management of TM and its complications and the use of antiresorptive agents, such as Bisphosphonates (BPs), as the first line-drug of treatment. In this article, we present the case of 45 years old-woman with TM and severe osteoporosis, with multiple fractures, albeit the assumption of BPs for many years. #ThalassemiaMajor #Osteoporosis #Hypoparathyroidism #Teriparatide #EndocrineGlands #Hormones #HormoneMetabolism #StructureAndPhysiochemicalProperties #HormonalReceptors #SignalingMechanisms #HormoneRegulatedGeneExpression #IntracellularSteroidAndLipidMetabolism #BoneAndMineralMetabolism #Infertility #Peertechz #PeertechzPublications #SexualDifferentiation #Puberty #PediatricEndocrinology #EndocrinePharmacology #MolecularEndocrinology #GastrointestinalEndocrinology #Neuroendocrinology #ComparativeEndocrinology #CardiovascularEndocrinology #ReproductiveEndocrinology

How Does Radiation Effect the Endocrine System? https://lnkd.in/enViNNGf A literature study of radiation effect on endocrine system is described.Endocrine disorders are common to people who they are exposed to radiation, it develops of hormone dysfunction and neoplasms in the irradiated gland and require long-term follow-up. Herein we discuss effects of radiation on the endocrine system. #Radiation, #Endocrinology, #Prevention

https://lnkd.in/gw2FZzys Article title: Thyrotoxicosis leading to Renal Tubular Acidosis presenting as periodic paralysis – A case report   Author(s): Sourya Sourabh Mohakuda; Rajiv Pakhetra; Naveen Yadav   Journal: International Journal of Clinical Endocrinology and Metabolism   Journal ISSN: 2640-7582 Abstract: Periodic flaccid paralysis is related to loss of tone and power transiently and which occurs repeatedly over time. Etiologies like channelopathies, myasthenia gravis and thyroid disorders are common. There have been case reports of thyroid disorders leading to periodic paralysis. The pathophysiology attributed to it is the increased uptake of potassium by the cells in the thyrotoxic state. Thyrotoxicosis is also an uncommon cause for distal renal tubular acidosis. In our case, we present a case of thyrotoxicosis leading to distal RTA presenting as periodic paralysis. On correction of thyrotoxic state with radioactive iodine ablation the renal tubular acidosis remmited both clinically and on arterial blood gas analysis. We report this case as there are very few cases of such nature which are reported worldwide. #PeriodicParalysis #Hypokalemia #RenalTubularAcidosis #EndocrineGlands #Hormones #HormoneMetabolism #StructureAndPhysiochemicalProperties #HormonalReceptors #SignalingMechanisms #HormoneRegulatedGeneExpression #IntracellularSteroidAndLipidMetabolism #BoneAndMineralMetabolism #Infertility #Peertechz #PeertechzPublications #SexualDifferentiation #Puberty #PediatricEndocrinology #EndocrinePharmacology #MolecularEndocrinology #GastrointestinalEndocrinology #Neuroendocrinology #ComparativeEndocrinology #CardiovascularEndocrinology #ReproductiveEndocrinology

The Marga and Walter Boll Foundation supports the study "You are what you eat - forever? Reversibility of dopaminenergic midbrain impairments in metabolic disease". This study investigates the question of whether the changes in the dopaminergic midbrain associated with the "Western lifestyle" and the resulting restrictions in motivation and learning behavior are permanent or reversible and up to what degree of severity of metabolic changes normalization can be achieved through preventive measures. The research project is being carried out at the Polyclinic for Endocrinology, Diabetology and Preventive Medicine at Cologne University Hospital and is designed as a randomized, controlled study with 120 participants over two years.   "Investigating the reversibility of early brain changes associated with the Western lifestyle will have implications for the development of preventive and therapeutic measures." Dr. Ruth Hanssen, Project Manager, Polyclinic for Endocrinology, Diabetology and Preventive Medicine, University Hospital Cologne   Find out more (in German language only): https://lnkd.in/ebwSGX3C   #BOLLFILTER

Harvard University: NMN helps with losing weight, reducing cholesterol , and lowering blood pressure In August 2023, Professor David Sinclair's research team at Harvard Medical School published a study in The Journal of Clinical Endocrinology & Metabolism. A number of overweight or obese adult subjects over 45 years were enrolled in a 28-day clinical study. The subjects consumed 2000mg NMN daily and their health indicators were continuously monitored. According to the study, a daily dose of 2000mg  NMN for 28 days is not harmful to humans. The study showed that for overweight or obese subjects, NMN helped to lose weight and reduced total cholesterol level, including low-density lipoprotein cholesterol, known as "bad cholesterol". In addition, NMN was also helpful in lowering blood pressure.

https://lnkd.in/gK9m66Yr Article title: Hyperparathyroidism and Asthenia. A New Deal?   Author(s): S Li Sun Fui; P Bonnichon   Journal: International Journal of Clinical Endocrinology and Metabolism   Journal ISSN: 2640-7582 Case report: The profile of primary hyperparathyroidism (PHPT) changed profoundly over the course of the twentieth century. The highly symptomatic forms reported in the 1960s have progressively been replaced by forms with few symptoms and in some cases totally asymptomatic forms. As of 1991, with the increasing frequency of these new forms, several consensus meetings designed to define the criteria for establishing the operability of minimally-symptomatic hyperparathyroidism have been organized [1]. #EndocrineGlands #Hormones #HormoneMetabolism #StructureAndPhysiochemicalProperties #HormonalReceptors #SignalingMechanisms #HormoneRegulatedGeneExpression #IntracellularSteroidAndLipidMetabolism #BoneAndMineralMetabolism #Infertility #Peertechz #PeertechzPublications #SexualDifferentiation #Puberty #PediatricEndocrinology #EndocrinePharmacology #MolecularEndocrinology #GastrointestinalEndocrinology #Neuroendocrinology #ComparativeEndocrinology #CardiovascularEndocrinology #ReproductiveEndocrinology

https://lnkd.in/gVcV_hit Article title: Parathyroid adenoma-An incidental diagnosis   Author(s): Nandini Chatterjee; Chandan Chatterjee   Journal: International Journal of Clinical Endocrinology and Metabolism   Journal ISSN: 2640-7582 Abstract: A 50 year old man was referred to us with inadequate control of blood pressure for last few years. He was being treated as a case of essential hypertension on a four drug regime. Subsequent work up led to the diagnosis of primary hyper parathyroidism due to left inferior parathyroid adenoma. #EssentialHypertension #Adenoma #Parathyroid #EndocrineGlands #Hormones #HormoneMetabolism #StructureAndPhysiochemicalProperties #HormonalReceptors #SignalingMechanisms #HormoneRegulatedGeneExpression #IntracellularSteroidAndLipidMetabolism #BoneAndMineralMetabolism #Infertility #Peertechz #PeertechzPublications #SexualDifferentiation #Puberty #PediatricEndocrinology #EndocrinePharmacology #MolecularEndocrinology #GastrointestinalEndocrinology #Neuroendocrinology #ComparativeEndocrinology #CardiovascularEndocrinology #ReproductiveEndocrinology

https://lnkd.in/gPWvnuMq Article title: Efficacies of Eruca sativa and Raphanus sativus Seeds’ Oils in Streptozotocin-Induced Diabetic Rats   Author(s): Osama M Ahmed; Eman S Abdel-Reheim; Mohammed B Ashour; Hanaa I Fahim; Hassnaa H Mohamed   Journal: International Journal of Clinical Endocrinology and Metabolism   Journal ISSN: 2640-7582 Abstract Objective: The study was planned to investigate the effect of Eruca sativa seeds’ oil (ESSO) and Raphanus sativus seeds’ oil (RSSO) on impaired glucose tolerance, lipid profile and oxidative stress in streptozotocin-induced diabetic albino rats. Also, the probable mechanisms of action were suggested. #EndocrineGlands #Hormones #HormoneMetabolism #StructureAndPhysiochemicalProperties #HormonalReceptors #SignalingMechanisms #HormoneRegulatedGeneExpression #IntracellularSteroidAndLipidMetabolism #BoneAndMineralMetabolism #Infertility #Peertechz #PeertechzPublications #SexualDifferentiation #Puberty #PediatricEndocrinology #EndocrinePharmacology #MolecularEndocrinology #GastrointestinalEndocrinology #Neuroendocrinology #ComparativeEndocrinology #CardiovascularEndocrinology #ReproductiveEndocrinology

https://lnkd.in/gdvkgPzk Article title: Myelofibrosis Associated, with Rickets, is it Hyperparathyroidism the Triggering Agent or Vitamin D and Hypocalcemia or Hypophosphatemia?   Author(s): Abdelwahab T H Elidrissy   Journal: International Journal of Clinical Endocrinology and Metabolism   Journal ISSN: 2640-7582 Abstract: Anemia due to iron deficiency is commonly associated with rickets, but rarely myelofibrosis was seen in infants with rickets in the hypocalcaemic phase. The aim of this review is to elucidate the mechanism of development of myelofibrosis in rickets. We reviewed the literature in PubMed with keywords myelofibrosis, hypocalcemia and anemia. The cases diagnosed as myelofibrosis in infants with evidence of rickets were studied. Hypocalcemia as it occurred in all the cases reported, it suggests that an association exists between myelofibrosis and hypocalcemia possibly as a consequence of a disturbed vitamin D metabolism. We could not find another evidence to support a direct relation between low calcium per se and myelofibrosis. #VitaminD #Myelofibrosis #Hypocalcaemia #Rickets #Osteomalacia #EndocrineGlands #Hormones #HormoneMetabolism #StructureAndPhysiochemicalProperties #HormonalReceptors #SignalingMechanisms #HormoneRegulatedGeneExpression #IntracellularSteroidAndLipidMetabolism #BoneAndMineralMetabolism #Infertility #Peertechz #PeertechzPublications #SexualDifferentiation #Puberty #PediatricEndocrinology #EndocrinePharmacology #MolecularEndocrinology #GastrointestinalEndocrinology #Neuroendocrinology #ComparativeEndocrinology #CardiovascularEndocrinology #ReproductiveEndocrinology