Medical Director, Grayken Center for Addiction at Boston Medical Center and Professor, Boston University
This study will change my practice: Feitong Lei and colleagues found that higher buprenorphine doses in the first 30 days of treatment are associeted with lower mortality for the subsequent 365 days. Not surprisingly, 8-16 mg was more effective than <8 mg--but there was actually also a substantial decrease in mortality associated with first-month doses >16 mg. We need to be prescribing higher doses right from the start in order to increase retention and reduce relapse.
This is exactly why our protocol at MATTERS Network emergency telemedicine calls for 8mg BID x 14 days for the initial RX! Great work!
Awesome! I have a retention study assessing flexible bup dosing up to 32 mg kicking off next week!
Thank you for sharing this!
Thank you for sharing this!
Everyone, everywhere deserves access to great mental health and addiction treatment. Now.
2moThanks for sharing Miriam Komaromy! We'll definitely incorporate this learning into the work we do every day. Great to see your name here. I hope you are well!