Kennedy Schaal’s Post

Early investigators of antisense oligos will remember this seminal paper by the Walders and appreciate its impact: Role of RNase H in hybrid-arrested translation by antisense oligonucleotides ROXANNE Y. WALDER and JOSEPH A. WALDER* Department of Biochemistry, University of Iowa Proc. Nati. Acad. Sci. USA Vol. 85, pp. 5011-5015, July 1988 https://lnkd.in/e4Tnz2PB Last paragraph: “For antisense oligodeoxynucleotides to be used to block the expression of selected genes within intact cells, it may be necessary to modify the oligonucleotide to decrease its rate of degradation and improve intracellular transport. An important corollary of our results is that such modified analogs must not only retain normal hybridization properties but should also form substrates that are recognized and cleaved by RNase H.”

Good luck Laura Miles presenting at International Congress for Breath Research Conference (IABR Breath summit) Indiana, US next week. The use of volatile organic compounds (VOCs) in exhaled breath as biomarkers for human health and disease offers a promising, non-invasive diagnostic tool that has the potential to transform clinical practice. Laura will be discussing how thermal desorption can be used to: - extend the dynamic range for breath analysis - generate pooled biological quality control samples that can be used for proficiency testing and longitudinal studies - easily address the high sample volumes generated from large scale breath analysis studies #BreathResearch, #Breathomics, #ThermalDesorptionWithoutCompromise

🗣💬 Join the OILS23 Innovation Day on Oct. 27th and listen to Antoine Gliksohn from Global Albinism Alliance, Dr. Muriel Elhai from Universitätsspital Zürich, Prof. Henry Sauermann from ESMT Berlin and Prof. Sabina Leonelli from University of Exeter discussing on citizen science as a way towards patient-oriented research! 👩⚕️🏥 Patient-oriented research aims to generate evidence that is relevant and applicable to the needs of patients, improve their health outcomes, and enhance their quality of life. Citizen science offers a unique opportunity to engage patients and their families in scientific research, potentially paving the way towards patient-oriented research. This approach can address the challenges of limited funding and difficulty engaging patients in research studies. 📊 🤝 However, data quality, the need for effective communication and the collaboration between scientists and citizen scientists remain challenges to be overcome! 💡 Check out our website and register now ➡ https://oils23.b2match.io 💡Use our EARLY BIRD promotion code "OILS23EarlyBird-SM" and use an 80% discount for our social media followers! 🗓 LAST CHANCE! The promotion is valid until TODAY and is limited to the first 10 participants!

Tomorrow marks the 4th of July, a day to celebrate America's independence and the innovative spirit that has fueled our nation. Here at BioHub Maryland, we're proud to carry that torch forward by fostering collaboration and accelerating talent in the life sciences industry. Celebrate with us by answering one of these questions in the comments below: • What scientific discovery are you most grateful for? • How do you see science shaping the future of America?

Discover the latest insights in life sciences conferences! BioInformatic's newest blog, "8 Key Highlights: Conferences and Exhibit Strategies in the Life Sciences," unpacks crucial trends for event planners and marketers. Highlights include: ✅ Preference for mid-sized conferences ✅ Virtual vs. in-person dynamics ✅ Unveiling attendee personas And more! Read the blog here: https://hubs.la/Q02ptGbY0

In 1675, Dutch haberdasher Antonie van Leeuwenhoek peered through a microscopic lens at some lake water and saw that it was teeming with life. Along with tufts of green algae, he saw thousands of tiny creatures he dubbed “animalcules.” Centuries later, we now know that Leeuwenhoek’s animalcules inhabit every surface, nook and cranny of the planet. The term “microbiome” was coined to describe the collective community of bacteria, viruses, fungi and other microbes that colonize a particular space or ecosystem—for example, a microbiome of the soil, or a microbiome of a body of water. Indoor spaces like homes, offices and hospitals also have distinct microbiomes, as do all the surfaces and objects within. And most multicellular life forms have their own microbiome—a collection of microbes that are co-dependent, adapting to and taking advantage of the conditions presented by the host. Microbiomes can have a profound impact on the host’s biology and health. Scientists at the University of Chicago and other institutions around the world are working to understand and catalog the microbiome, and to apply these insights to interventions and biotherapeutics to maintain health and to prevent and treat disease.

In 1675, Dutch haberdasher Antonie van Leeuwenhoek peered through a microscopic lens at some lake water and saw that it was teeming with life. Along with tufts of green algae, he saw thousands of tiny creatures he dubbed “animalcules.” Centuries later, we now know that Leeuwenhoek’s animalcules inhabit every surface, nook and cranny of the planet. The term “microbiome” was coined to describe the collective community of bacteria, viruses, fungi and other microbes that colonize a particular space or ecosystem—for example, a microbiome of the soil, or a microbiome of a body of water. Indoor spaces like homes, offices and hospitals also have distinct microbiomes, as do all the surfaces and objects within. And most multicellular life forms have their own microbiome—a collection of microbes that are co-dependent, adapting to and taking advantage of the conditions presented by the host. Microbiomes can have a profound impact on the host’s biology and health. Scientists at the University of Chicago and other institutions around the world are working to understand and catalog the microbiome, and to apply these insights to interventions and biotherapeutics to maintain health and to prevent and treat disease.

In todays NORDIC LIFE SCIENCE NEWS we can read more about Neola Medical and the support from Impact1 at Stanford Biodesign 🇺🇸 💡 👶 --- I dagens NORDIC LIFE SCIENCE NEWS kan vi läsa mer om Neola Medical och stödet från Impact1 at Stanford Biodesign 🇺🇸 💡 👶 #medtech #healthtech #pediatricinnovation

#MasterControl #MastersSummit2024 The early bird gets the biggest early savings. Register now for 2024