ImmunoACT’s Post

Explore DNA methylation and its intricate role in cancer, where dysregulation of 5-methylcytosine (5mC) impacts gene regulation. Aberrant methylation patterns in CpG dinucleotides contribute to tumor suppressor gene silencing and oncogene activation. Seraseq® Methylated and Unmethylated ctDNA Mutation Mixes provide unparalleled insight into CpG methylation status, revolutionizing cancer research and personalized treatment approaches. Read our blog and discover the potential of DNA methylation in cancer diagnostics and therapy: https://hubs.ly/Q02vLxb20 #Methylation #GeneRegulation #DNAModification #CancerResearch #Epigenetics

🧬 𝐍𝐞𝐰 𝐅𝐃𝐀 𝐚𝐩𝐩𝐫𝐨𝐯𝐚𝐥 𝐟𝐨𝐫 𝐨𝐧𝐜𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐚𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐢𝐧 𝐭𝐡𝐞 𝐜𝐞𝐥𝐥 𝐚𝐧𝐝 𝐠𝐞𝐧𝐞 𝐭𝐡𝐞𝐫𝐚𝐩𝐲 𝐬𝐩𝐚𝐜𝐞 Last week marked a significant victory for 𝐈𝐨𝐯𝐚𝐧𝐜𝐞 𝐁𝐢𝐨𝐭𝐡𝐞𝐫𝐚𝐩𝐞𝐮𝐭𝐢𝐜𝐬, 𝐈𝐧𝐜., which secured FDA approval for 𝐀𝐌𝐓𝐀𝐆𝐕𝐈™ (𝐥𝐢𝐟𝐢𝐥𝐞𝐮𝐜𝐞𝐥) for the treatment of patients with skin cancer. This is the first individualised tumour-infiltrating lymphocyte (TIL) therapy to be introduced to the market, bringing the total number of CGT therapies in the US to 35. This approval, along with the recent EMA endorsement of 𝐂𝐚𝐬𝐠𝐞𝐯𝐲 by 𝐕𝐞𝐫𝐭𝐞𝐱 𝐏𝐡𝐚𝐫𝐦𝐚𝐜𝐞𝐮𝐭𝐢𝐜𝐚𝐥𝐬 for the European market, clearly indicates progress in the cell and gene therapy space.

Explore DNA methylation and its intricate role in cancer, where dysregulation of 5-methylcytosine (5mC) impacts gene regulation. Aberrant methylation patterns in CpG dinucleotides contribute to tumor suppressor gene silencing and oncogene activation. Seraseq® Methylated and Unmethylated ctDNA Mutation Mixes provide unparalleled insight into CpG methylation status, revolutionizing cancer research and personalized treatment approaches. Read our blog and discover the potential of DNA methylation in cancer diagnostics and therapy: https://hubs.ly/Q02vLmck0 #Methylation #GeneRegulation #DNAModification #CancerResearch #Epigenetics

With #Lentiglobin and #ExaCel opening the new landscape of care for sickle cell patients, the industry is again forced to juxtapose transformative benefits with lackluster patient access. This is a great article laying out how barriers to access have come to be and how we can overcome them. #cellandgenetherapy #sicklecell #patients #patientcare #patientaccess #genetherapy

Day 2 of our Oncology Insights event! Today, explore recent advancements in viral-vector cell and gene therapy technologies and how to leverage them for the successful development of personalized cancer therapies. Save my spot: https://hubs.ly/Q02vqK620 #CancerResearch #OncologyResearch #PrecisionMedicine #Genomics #GeneTherapy #CellTherapy

👏👏👏happy Sunday!! #multiomicspapers challenge! BRD4 degradation and lung cancer therapy! PROTACT technology in drug development, happy to hear your thoughts about! 🔥🔥📌 Mechanism of action of BRD4: binds enhanced of oncogenes like cMyc, recruiting RNA pol2, enabling and enhancing transcription ! Epigenetics and gene regulation 🎯 💡💡💡Looking the phenotype with proteins will help to assess Omics perspective to the mechanism and disease progression. #multiomics #olinkproteins #epigenetics https://lnkd.in/dgVpkud7

Dive into innovation at TIDES 2024! Join us as we unveil groundbreaking insights in our breakfast spotlight presentation "Harnessing RNA to Simplify and Advance Gene Therapy" and our two posters, "Neoantigen vaccines: A promising cancer therapy" and "Integrated novel IVT RNA platforms to accelerate research and therapeutics development." Don't miss the chance to connect with our team! #TIDES2024 #oligonucletoide #peptide #genomeediting #mRNA

Embrace the era of certainty with Digital PCR! Elevate your research with the precision and sensitivity of dPCR for higher reproducibility across various therapeutic areas like Cell and Gene Therapy, Oncology, Monoclonal Antibodies, Vaccine development and more. Connect with us to learn more about how dPCR can help you with your next breakthrough discovery: https://hubs.ly/Q02Gn_-00 #ClinicalResearch #Genomics #DigitalPCR