Certest Biotec, S.L.’s Post

Our project about Phase Rectified Signal Averaging and Joint Symbolical Analysis is accepted to be presented at European Study Group on Cardiovascular Oscillations (ESGCO 2024)

Are all CRFs created equal, or do you need different approaches for different CRFs? Listen to Allison Hubel, PhD, President of the Society for Cryobiology discuss this as the last CryoChats™ entitled: "Assessing Operational Risk and Clinical Impact. ❄ Don't miss the opportunity to engage with industry experts by not registering for the upcoming CryoChats™! Registration is now open: https://lnkd.in/gUXVHa83 Upcoming CryoChats™ Schedule:  7/31 | Cryopreservation Scaling Up 8/28 | Gap Analysis: Inputs & Outputs 9/25 | Reinventing (the Cell Assay) Wheel Dominic Clarke, Marty Giedlin, PhD, Jeffrey D. Allen, John Baust, Marc J. Centrella, Scott Fisher, John Bonham-Carter, Mike O'Mara, Priya Baraniak, Ph.D., Russ Straate, Aby J. Mathew, PhD

🚨 Last chance to register for an upcoming webinar and learn how mass photometry can streamline mAb analytics.  Join this webinar, led by Amy Chau, Ph.D. (Field Application Specialist at Refeyn), as she discusses the versatility of mass photometry – a novel, column-free technology - in forced antibody degradation studies. Discover how these studies can be rapidly performed with mass photometry – which can evaluate mAb sample quality in solution, using minimal sample amount.  🧪 Learn also how mass photometry complements SEC, as well as its broader applications for antibody characterization, including the assessment of antibody-antigen interactions. 👉 https://lnkd.in/dGEaX3tt

🏆 The Van Bekkum Award is the most prestigious EBMT award for the best abstract submitted to the physician’s programme and is selected by the EBMT Board of Association and Scientific Committee. 👀 Watch the EBMT TV 📺 interview with this year's winner Leslie Kean, who tells us more about her research and abstract "Large-Scale Tcr Deep Sequencing Reveals A T Cell Diversity Bottleneck With Post-Transplant Cyclophosphamide With Implications For Efficacy And Toxicity: Results Of The Bmt-Ctn 1801 Study". ➡️ https://lnkd.in/e2wEc9ii

🔬 Exciting Update on #BSMO24! Brigitte Maes shares insights into the groundbreaking #BALLETT study, powered by @mybsmo and employing TSO500 for comprehensive genomic profiling. All results from TSO interpreted by our #oncokdm software. 🧬 Key Highlights: 🔍 Actionable Variants: Detected in an impressive 83% of patients, underlining the study's precision in identifying relevant genomic information. 💡 Treatment Recommendations: Remarkably, 70% of patients received tailored treatment recommendations based on genomic profiling. ⏭️ Follow-up Success: Encouragingly, 21% of patients have already initiated the recommended treatments, emphasizing the study's impact on patient care and outcomes. 🤔 Question: When will this kind of tumor profiling be reimbursed in Belgium? The urgency for widespread access to such innovative and personalized approaches to treatment is undeniable. Kudos to the dedicated team behind #BSMO24 for advancing precision medicine and paving the way for personalized treatment strategies! 🚀🌐 #GenomicProfiling #PrecisionMedicine #HealthcareInnovation #MedicalResearch

New research in Microbiology Spectrum from IceLab members Kemal Avican, Martin Rosvall, Maria Fällman, alongside Johan Normark and featuring multidisciplinary postdoctoral fellow Leyden Fernandez, one of the first fellows to join IceLab with our Kempe foundations funded postdoctoral program. Unveiling gene co-expression networks in bacterial pathogens has the potential for gaining insights into their adaptive strategies within the host environment. The authors developed Co-PATHOgenex, an interactive and user-friendly web application that enables users to construct networks from gene co-expressions using custom-defined thresholds (https://lnkd.in/gPKdaRWa). The incorporated search functions and visualizations within the tool simplify the usage and facilitate the interpretation of the analysis output. Co-PATHOgenex also includes stress stimulons for various bacterial species, which can help identify gene products not previously associated with a particular stress condition. This tool aids in deepening our understanding of bacterial adaptation to stress conditions and in deciphering complex transcriptional responses of bacterial pathogens. https://lnkd.in/gxVxybYP

I am excited to share the newest publication from our lab in Blood describing a novel approach for targeting the platelet and preventing thrombosis. this study, led by Livia Stanger, a graduate student in the lab, details for the first time the compound CS585, a new compound that is highly selective for the prostacyclin receptor. CS585 was shown not only to be selective for the IP receptor, but is available orally and demonstrates sustained and reversible regulation of platelet activation and thrombosis. https://lnkd.in/gGzPmUEb

In May, about 70 experts from academia, government, industry, and professional organizations met with the goal of developing a working definition or framework for the term “precancer.” Read the executive summary of the Precancer Atlas Think Tank Meeting: https://buff.ly/467LviZ

Today I presented my research at ESHG 2024 in Berlin on identifying new diagnostic regions in Diamond Blackfan Anaemia by investigating GATA1 binding in red blood cells

A High Content Imaging contest offers a unique challenge as the microscopy is required to still be screened at scale and relevant in drug discovery. Sarah's image of iCell GlutaNeurons is a great example. These are cortical neurons that are derived from IPSC's that allow the formation of functional neuronal networks. These cells can be used to study healthy network formation and branching of neurons as well as the functional excitory behavior for normal or seizurogenic activity. Did you know inhibition of neuronal branching in vitro can be an indicator of dizziness and balance issues in a drug treatment?