📢 Revolutionizing Lentiviral Vector Production for Better Therapies 📰 Lentiviral vectors are important tools in cell and gene therapy, but current production processes have room for improvement. 🧬 Scalability, productivity, and process yield are some of the challenges faced in lentiviral vector production. 🔬 Bioprocessing technologies such as high-titer suspension cells and single-use bioreactors can help optimize the production process. 💻 Process control software and artificial intelligence AI can also assist in improving vector quality and efficiency. 🚀 The ultimate goal is to create a robust and easily scalable manufacturing platform to ensure safety and efficacy of therapies. 🔬🧪🧬 #LentiviralVectors #Bioprocessing #CellTherapy #GeneTherapy #AI #BioprocessUpdates #LentiviralVectors #Bioprocessing #CellTherapy #GeneTherapy #AI #Scalability #Productivity #ProcessYield #HighTiterSuspensionCells #SingleUseBioreactors #ProcessControlSoftware #ArtificialIntelligence #VectorQuality #Efficiency #ManufacturingPlatform #SafetyAndEfficacy ▷ Read the full article here: 📎 https://lnkd.in/dhR8dRWV
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📢Robots and AI Revolutionize Cell and Gene Therapy Manufacturing 🤖 Researchers suggest that robots and artificial intelligence can address manufacturing challenges in cell and gene therapy. 🔬 The European Committee of ISCT and EBMT highlights the bottlenecks in manufacturing. ⬆️ The rapid growth of the sector necessitates skilled personnel and increased production demand. 🌍 Currently, there are only a few approved therapies, but the market is expected to expand. 🤖 Automation and robotization, combined with AI, can improve production efficiency and reduce costs and variability. #BioprocessUpdates #robots #artificialintelligence #celltherapy #genetherapy #manufacturing #research #bottlenecks #growth #skilledpersonnel #productiondemand #approvedtherapies #marketexpansion #automation #robotization #productionefficiency ▷ Read the full article here: 📎 https://lnkd.in/d_MpVg2x
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"The majority of cell and gene therapies are discovered and developed in academic settings characterized by complex and highly manual processes. With highly skilled scientists physically implementing each step, these processes aren’t scalable at a commercial level." We can't wait for more companies and organizations to adopt technologies like Krakatoa™, our benchtop media maker, that completely automate critical upstream processes. 2024 also promises much in the development of AI, which we can only see further contributing to decentralized manufacturing and eliminating human error. #decentralizedmanufacturing #celltherapy #bioprocessing https://hubs.ly/Q02f2Hy60
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Restoring the sight of patients with the help of #GeneTherapy? What sounded like science fiction a few years back, today is an example of #WhatTechCanDo to improve our lives and health. So, it’s no wonder, that #CES2024 has its own conference track on the intersection of technology and healthcare. But despite the healthy outlook on the growth of gene therapy as a sector, production and scale-up capabilities remain in early stages as technology is advancing faster than manufacturers can adapt. ➡ Our Senior Partner Morris Hosseini and Principal Stephan Fath therefore explored the challenges and trends in #manufacturing these innovative treatment opportunities to make the promise and potential of gene therapy a reality for patients worldwide. 💡 You want to navigate this rapidly developing field in healthcare? Download our analysis on our website: https://lnkd.in/en8nEsVt #RolandBerger
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|Solution Architect-SAP S/4 OTC,BTP |Quantum Computing's |AI/ML |Quantum Advisory-Govt Org|| EB1A "Einstein Visa" Recipient |CENG(I)|TOGAF|FBCS|FIETE |AAAS|FICS|FRSS|SMIEEE|(Lets Adopt Smart Technologies to Human Lives).
Thanks, SAP AG, for the solutions to support healthcare and Cell and Gene Therapy Orchestration, of course we can do much more and superb best for healthcare services and let's apply the greatness of " Quantum Computing's and Quantum Applications to Mankind". Thanks God, for your support and blessings, as I could complete the training and Record of Achievement on "SAP Cell and Gene Therapy Orchestration."
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Don’t Let Problems Surprise You: Early Problem Detection Makes Your Life Easier! In the world of cell and gene therapy manufacturing, the stakes are high. But guess what? With Process Analytical Technology (PAT), you can dodge those headaches, save time, and keep your budget controller happy. Why PAT is a Game-Changer: 1. Save Time, Save Money: -- Online Monitoring: PAT tools, like the Ovizio Imaging System, keep an eye on your cell cultures 24/7. They catch issues before they turn into big problems. -- Close Loop Control: Automatic adjustments mean optimal conditions are always maintained. No more manual tweaking – it’s hands-free! -- Automation: From data collection to analysis, automation ensures everything runs smoothly without constant supervision. 2. Keep Your Product Safe: -- Early Detection: Spotting issues early means fewer defective batches. Your therapies remain top-notch, and your patients stay safe. -- Hands-Free Operation: With PAT, especially systems like Ovizio, you minimize contamination risks and human error. Your cultures thrive in a stable, controlled environment. 3. Boost Efficiency: --Real-Time Data: Continuous monitoring provides instant feedback, allowing for quick decision-making and immediate action. --Streamlined Processes: With automated and hands-free systems, your workflow is smoother, faster, and more efficient. The Takeaway: Early problem detection not only makes your life easier but also ensures your cell and gene therapy manufacturing is efficient, cost-effective, and reliable. Invest in PAT, like the Ovizio Imaging System, and see the difference for yourself. #GeneTherapy #CellTherapy #ProcessAnalyticalTechnology #OnlineMonitoring #CloseLoop #Automation #HandsFree #EarlyDetection #OvizioImaging #HealthcareInnovation
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This is a call to Cell and Gene Therapy companies - if you need multiparametric cell sorting, Cellular Highways - Highway1 can be up to 4x faster to produce a dose (based on an output of 60 million sorted cells*) compared to other solutions. Offering potential production cost savings of over 80% per dose (based on an annual requirment of 10,000 doses**). Don't just take my word for it - ask for a demo and see for yourself why the Highway1 is fast becoming the preferred, scalable solution for many companies and researchers, from early discovery through to manufacture. *includes both sorting time (enabled by VACs - Vortex Actuated Cell Sorting) and process time ** calculated based on consumable costs, HR/operator cost and facilities costs (data collected over 2 years from numerous real world head-to-head comparisions and published specifications)
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The ISCT, International Society for Cell & Gene Therapy global community affirms its dedication to realizing the promise of advanced therapies. Our journey through the halls of academia, to the bedside, and into the industrial ecosystem has been marked by an unyielding commitment to relentless innovation and excellence. But the journey to a new standard of healthcare is upon us. We need the technology to enable access and reduce costs. Digital infrastructure, analytical technologies for release, and manufacturing automation are some of the key bottlenecks for us to overcome. We need to work together to innovate and develop further. Our readiness for this new phase involves a comprehensive approach, I believe there are six elements to tackle: 1. Academic advances 2. Technological advances 3. Global collaboration 4. Regulatory alignment 5. Educational outreach 6. Economic adaptation You can see my full manifesto in my previous post or I can email it to you. Voting is open until Friday, March 22nd at https://lnkd.in/eNVEriY3 I would love to hear your feedback. If you have any questions or thoughts, let’s talk! #ISCT #ISCTelections #technology #innovation #celltherapy
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🔬 The Alliance for Regenerative Medicine's Advanced Manufacturing in Cell and Gene Therapies Workshop begins today, May 16th! 🧬 Join us in person or virtually as Marinna Madrid, PhD, Co-Founder & Chief Product Officer at Cellino, speaks on "Reimagining Biomanufacturing of Autologous iPSC-Based Therapies: Using AI to Increase Scale & Consistency" from 1:30-3:10 PM EDT. Hear how our #AI- and laser-based processes are transforming #biomanufacturing solutions for personalized regenerative medicines. 🚀 🗓️ Register for this 1.5-day ARM workshop in #RockvilleMD, or join the live stream today and tomorrow, May 16-17, 2024. Explore the agenda, speakers, and registration details here: bit.ly/43QkzV5 #AllianceRM #RegenMed #Biotech #Innovation #Autologous #AI #MachineLearning #PersonalizedMedicine #YourCellsYourCure #CellinoBio
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