๐๐-๐ฑ๐ฟ๐ถ๐๐ฒ๐ป ๐บ๐ผ๐ฑ๐ฒ๐น ๐ถ๐ฑ๐ฒ๐ป๐๐ถ๐ณ๐ถ๐ฒ๐ ๐ฝ๐ผ๐๐ฒ๐ป๐ ๐ฐ๐ฎ๐ป๐ฐ๐ฒ๐ฟ-๐ธ๐ถ๐น๐น๐ถ๐ป๐ด ๐ถ๐บ๐บ๐๐ป๐ฒ ๐ฐ๐ฒ๐น๐น๐ ๐ณ๐ผ๐ฟ ๐ฝ๐ฒ๐ฟ๐๐ผ๐ป๐ฎ๐น๐ถ๐๐ฒ๐ฑ ๐ถ๐บ๐บ๐๐ป๐ผ๐๐ต๐ฒ๐ฟ๐ฎ๐ฝ๐ ๐น ๐ง๐ฎ๐น๐ธ ๐๐ถ๐๐ต ๐ฎ๐ป ๐ฒ๐ ๐ฝ๐ฒ๐ฟ๐ ๐https://lnkd.in/e52sdG3P In a landmark achievement reported in the prestigious journal Nature Biotechnology, scientists at Ludwig Cancer Research have unveiled a transformative predictive model empowered by artificial intelligence (AI). Led by Alexandre Harari and Rรฉmy Pรฉtremand, the team has devised an innovative approach to identify the most potent immune cells for combatting cancer, heralding a new era in personalized immunotherapies. At the core of this pioneering work lies the recognition of T cells, the frontline warriors of the body's immune system. Specifically, the focus is on tumor-infiltrating lymphocytes (TILs), tasked with penetrating solid tumors and eradicating cancerous cells. However, not all TILs possess the requisite prowess to effectively target tumors, underscoring the need for precise identification of those with optimal tumor-killing capabilities. Enter TRTpred, the novel AI-driven predictive model developed by Harari and his team. Leveraging sophisticated machine learning algorithms, TRTpred analyzes T cell receptors (TCRs) to discern their tumor reactivity. Drawing on data from 235 TCRs obtained from patients with metastatic melanoma, the model distinguishes between tumor-reactive and non-reactive T cells with remarkable accuracy, offering invaluable insights into the intricate dynamics of immune responses in cancer. The implications of this breakthrough are profound. By harnessing the power of AI, researchers can now pinpoint the most potent immune cells for inclusion in personalized cancer immunotherapies, offering renewed hope to patients facing this formidable disease. This innovative approach represents a paradigm shift in cancer treatment, marking a significant step towards more effective and targeted therapies tailored to the unique cellular makeup of each patient's tumors. As the scientific community celebrates this milestone, the journey towards transformative cancer care continues. With each discovery, we move closer to a future where AI-driven precision medicine empowers patients and clinicians alike in the fight against cancer. The implications are far-reaching, promising to reshape the landscape of oncology and usher in a new era of hope and healing. ๐ Contact BIOBOSTON CONSULTING today or visit our website to learn more about how we can support your organization. #pharmaceuticals #biotechnology #medicaldevices #consulting #fda #quality #compliance #qualityassurance #regulatoryaffairs
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Witness an extraordinary revolution in the world of oncology, driven by cutting-edge technologies and groundbreaking research. Gone are the days of one-size-fits-all treatments, as we step into an era of personalized medicine and precision-based diagnostics. Genomic testing and liquid biopsies are morphing the landscape of cancer diagnosis, offering insights into genetic mutations and enabling early intervention. Meanwhile, innovations such as the NCIโs ComboMATCH Initiative and targeted therapies like dabrafenib and trametinib are combating cancer's notorious resistance to treatment. On the frontiers of cancer care, immunotherapy is ushering us into a new dawn. With the development of mRNA cancer vaccines and CAR T-cell therapies, oncologists are harnessing our own immune system to fight the disease. Radiopharmaceuticals and oncoviruses are joining the battle against cancer, delivering radiation directly to cancer cells and stimulating immune responses. Furthermore, the role of diet and the gut microbiome in influencing cancer treatment efficacy is being increasingly recognized. Digital advances like telehealth, along with personalized medicine, are reshaping cancer care. Genomic testing is guiding treatment approaches and mRNA technology is being explored for personalized cancer vaccines. Prepare to delve into this fascinating world where technology meets medicine and optimism replaces dread. The fight against cancer is at a pivotal moment. Will you join us in spreading the word? #OncologyRevolution #CuttingEdgeTech #Immunotherapy #GenomicTesting #LiquidBiopsies #TargetedTherapies #Radiopharmaceuticals #Oncoviruses #MicrobiomeResearch #Telehealth #PersonalizedMedicine Read more on our blog: https://lnkd.in/ee-48HBX
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๐ **Revolutionizing Cancer Care with Precision Research** ๐ The forefront of cancer treatment is undergoing a transformation thanks to the latest advancements in precision research. Hereโs how cutting-edge innovations are making a significant impact: ๐ฌ **Tailored Treatments**: Precision medicine is all about personalization. By understanding the unique genetic makeup of each patientโs cancer, treatments are becoming more effective and targeted, leading to better outcomes and fewer side effects. This approach is revolutionizing how we think about cancer care. ๐งฌ **Genomic Profiling**: Advanced genomic profiling techniques allow us to identify specific mutations and alterations in cancer cells. This detailed knowledge enables oncologists to select the most appropriate therapies, ensuring that patients receive the most effective treatment for their specific type of cancer. ๐ **Targeted Therapies**: New drugs and therapies are being developed to target cancer cells with pinpoint accuracy, sparing healthy cells and reducing collateral damage. These targeted therapies are proving to be game-changers, especially for cancers that were previously difficult to treat. ๐ **Liquid Biopsies**: Precision research is also enhancing early detection through liquid biopsies. These non-invasive tests analyze biomarkers in blood, providing crucial insights into cancer presence and progression. Early detection means early intervention, significantly improving survival rates. ๐ก **Predictive Analytics**: Utilizing big data and AI, predictive analytics can forecast how different cancers will respond to various treatments. This foresight helps in crafting the most effective treatment plans, giving patients a personalized roadmap to recovery. The future of cancer treatment lies in precision research, offering a beacon of hope for millions. These advancements are not just scientific achievements; they are life-changing developments that bring us closer to a world where cancer can be effectively managed and ultimately cured. Join us in celebrating these breakthroughs and supporting the ongoing efforts in precision cancer research. Together, we can make a difference. #CancerResearch #PrecisionMedicine #GenomicProfiling #TargetedTherapies #LiquidBiopsies #PredictiveAnalytics #Innovation #Healthcare #MedicalResearch #Hope #EndCancer
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Revolutionizing the Fight Against Cancer is more than just a catchy title - it's a testament to the exhilarating pace of development in the world of oncology. Ground-breaking precision therapies, artificial intelligence integration, and emerging immunotherapies are transforming the battlefront against this formidable disease. Personalized treatment options have never been more abundant, thanks to the surge in precision oncology therapies. Imagine a world where cancer treatment is tailored to your unique genetic profile - this is the dawn of precision oncology. But as we herald these advancements, let's not forget the imperative for equitable cancer care. In a time of unprecedented breakthroughs, we must ensure that these benefits are accessible to all, regardless of race or ethnicity. Next, the battleground is shifting its focus to immunotherapy and liquid biopsies. Utilizing the body's own immune response against cancer cells, and detecting genetic alterations in the blood, these techniques are revolutionizing cancer diagnostics and treatment. Artificial intelligence and genomics are also joining the front lines, predicting treatment responses and identifying optimal therapy combinations based on individual molecular profiles. Meanwhile, therapeutic advancements range from nanotechnology to drug repositioning, fortifying our arsenal against cancer. As we look to the future, we see a landscape marked by personalized vaccines, gene editing technologies, and liquid biopsies. These developments promise unprecedented personalization and precision and signify hope for patients worldwide. While challenges remain, these strides in science and technology are revolutionizing the fight against cancer, offering a beacon of hope to those battling this disease. #PrecisionOncology #ArtificialIntelligence #Immunotherapy #LiquidBiopsies #Genomics #EquitableCancerCare #Nanotechnology #DrugRepositioning #PersonalizedVaccines #GeneEditing #CancerResearch #FutureOfOncology Read more on our blog: https://lnkd.in/dD6QU_r6
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Headhunting Talented Individuals within Clinical Operations & Clinical Development for growing organizations across the US & Europe
Cancer management is on the cusp of a major shift - thanks to advances in MRD (Minimal Residual Disease) testing. The Figures tell a staggering story, with the market expanding from $1.67 billion to a projected $6.67 billion by 2033 ๐ MRD testing stands out as techniques like PCR, NGS, and flow cytometry delve deep, detecting residual cancer cells that traditional methods may miss. This isn't just about monitoring, there is more going on. it's about prognosis and treatment precision. Early, sensitive detection means that treatments can be fine-tuned, revolutionizing patient outcomes. It's paving the way for tailor-made therapies, driving survival rates up which is what we all want to be seeing! โ As we move forward, tech advancements are racing to keep up with rising global cancer rates, striving for MRD diagnostics that are ever more sensitive and accurate ๐๐ป This isn't just any industry trend, it's the future. This allows each step in care to be informed by the detection of minimal residual disease. By the looks of it, the MRD testing market isn't just growing, it's redefining the landscape of oncology and patient care ๐๐ผ #MRDTesting #CancerCareEvolution #Oncology #PersonalizedMedicine #MedicalInnovation #ClinicalTrials #ClinicalResearch #LifeScience #Elixirassociates #StaffingPartner
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Healthcare Executive | Corporate Affairs | Communications | Patient Advocacy | Health Equity | Government Affairs | Sustainability | Professor of Global Health and Policy | Board Member | Former Ex-Pat | MBA | FNYAM
#Cancer is close to many of us - but especially to people living in lower and middle-income countries (#LMICs). Of the 10 million annual #cancer deaths globally, 70% happen in LMICs. But through science, compassion and better healthcare, change is possible. Cancer is the disease area that has the most treatments in the pipeline, with thousands of #medicines and #vaccines in development by our industry. Through translational medicine, scientists are deepening their understanding of disease biology and uncovering novel biomarkers to help predict how cancer patients will respond to treatment. Innovators like Bristol Myers Squibb are working on collaborations from across the global cancer community to improve patient outcomes by innovating more efficient and effective cancer care. Through collaborative projects like All.Can International, City Cancer Challenge, and Access Accelerated , we are helping to overcome systemic challenges for patientsโ access to care globally-from screening, early detection and diagnosis through to improving #patient support and navigation and optimizing care management. All patients should have access to the best available care, including transformational medicines, regardless of where they live. In this article published by IFPMA, Amadou Diarra, Senior Vice-President, Global Policy, Advocacy and Government Affairs, at BMS explores a new era for cancer treatment. #AlwaysInnovating #BMS_Employee #FutureProofingMedicines
Ushering in a new era for cancer therapy - IFPMA
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Embrace the Future of Cancer Treatment: Unveiling the Power of Neoantigen Prediction. In the ever-evolving landscape of medical advancements, neoantigen-based therapeutics stand out as a promising approach. Jeffrey Brabec, Ph.D., and Scientific Partner at Velsera, explores this innovative field, offering a perspective on the future of cancer care. Neoantigen-based therapies hold the potential to revolutionize cancer treatment by unlocking a realm of personalized, precision medicine. Imagine therapies tailored to each patient's unique genetic makeup - a future that's becoming reality. At Velsera, we've been at the forefront of neoantigen prediction research. Our participation in the Tumor Neoantigen Selection Alliance challenge has yielded remarkable insights. Discover the intricate process that's shaping the future of cancer treatment. Read the full blog here to explore the complexities of mutational events, the role of haplotype phasing, harnessing RNA expression, and the challenges we face in neoantigen prediction. https://lnkd.in/g4JBAQcB #Neoantigens #PrecisionMedicine #CancerMoonshot #EraofVelsera
Neoantigen Prediction to Drive the Next Generation of Cancer Treatments
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Solutions Manager @ Lifebit | Helping researchers find reliable and reproducible bioinformatics solutions | RStudio Tidyverse Instructor
Howdy Folks! I've been on vacation for the past week and did my best to stay off LinkedIn as well as an exercise in work-life balance. Now that I'm back I wanted to share this post I wrote about Velsera's neoantigen prediction workflow. As a computational neuroscientist the closest I got to immunology was finding out a gene of interest happened to be involved in some sort of cancer pathway so working on this project has been a crash course in cancer biology and immunology! Accurate neoantigen prediction is critical for the creation of cancer vaccines to effectively target the major tumor type while also avoiding cross-reactivity that targets non-cancerous cells in the body. Our neoantigen prediction workflow puts the phrase "bench to bedside" into action as it starts with raw patient whole genome and RNAseq data and ends with candidate neoantigen targets that can be validated at the bench and used in a cancer vaccine for a specific patient. This is just one of the many ways Velsera is helping to support #precisionmedicine efforts. Interested in learning how Velsera can support your precision medicine pursuits reach out and I'd be happy to connect you to our stellar sales team ๐คฉ. #EraOfVelsera #genomics
Embrace the Future of Cancer Treatment: Unveiling the Power of Neoantigen Prediction. In the ever-evolving landscape of medical advancements, neoantigen-based therapeutics stand out as a promising approach. Jeffrey Brabec, Ph.D., and Scientific Partner at Velsera, explores this innovative field, offering a perspective on the future of cancer care. Neoantigen-based therapies hold the potential to revolutionize cancer treatment by unlocking a realm of personalized, precision medicine. Imagine therapies tailored to each patient's unique genetic makeup - a future that's becoming reality. At Velsera, we've been at the forefront of neoantigen prediction research. Our participation in the Tumor Neoantigen Selection Alliance challenge has yielded remarkable insights. Discover the intricate process that's shaping the future of cancer treatment. Read the full blog here to explore the complexities of mutational events, the role of haplotype phasing, harnessing RNA expression, and the challenges we face in neoantigen prediction. https://lnkd.in/g4JBAQcB #Neoantigens #PrecisionMedicine #CancerMoonshot #EraofVelsera
Neoantigen Prediction to Drive the Next Generation of Cancer Treatments
26660662.hs-sites-eu1.com
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In the war against cancer, groundbreaking strides are being made that hold the promise of a future where cancer is not a death sentence. Armed with a deeper understanding of cellular dynamics, we're witnessing paradigm shifts in genomics, immunotherapy, precision medicine, and advanced diagnostics. Key findings in cancer biology, aided by technologies that map genetic alterations, are illuminating the blueprint of cancer development. This is decoding the secrets of its progression, promising new paths to stopping it in its tracks. Oncogenic fusion genes, for instance, have opened doors to targeted therapies, transforming cancer treatment like never before. Immunotherapy is another game-changer. It's harnessing our body's defense mechanisms, offering a potent and individualized approach to combatting cancer. Innovations like immune checkpoint inhibitors and personalized cancer vaccines are showing remarkable responses in certain cancer types. We're also witnessing the power of precision medicine. By using genetic profiling and targeted therapies, treatments can be tailored to individuals, not just illnesses. This personalization strategy is improving patient outcomes and inspiring hope. In the realm of early detection, liquid biopsies are making strides. By diagnosing the disease earlier than traditional methods, monitoring treatment response, and providing insights into tumor heterogeneity, they're revolutionizing cancer detection and monitoring. As we look to the future, innovative technologies like AI and machine learning, nanotechnology-based drug delivery systems, and more are set to redefine our approach to cancer. The quest continues, but with these revolutionary advances, we march toward a future where cancer is effectively managed, if not eradicated. Let's celebrate the hope these breakthroughs offer to millions of patients worldwide. Discover more on this enlightening journey in our latest blog article: [#CancerResearch #Immunotherapy #PrecisionMedicine #Genomics #CancerBiology #AdvancedDiagnostics #BreakthroughsInCancerTreatment] Read more on our blog: https://lnkd.in/eEEhYVX4
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